A stepwise approach toward closed-loop blood glucose control for intensive care unit patients: Results from a feasibility study in type 1 diabetic subjects using vascular microdialysis with infrared spectrometry and a model predictive control algorithm

Journal of Diabetes Science and Technology

Volumn 5, Issue 4, 2011, Pages 901-905

  Feichtner, Franz ^a   Mader, Julia K ^b   Schaller, Roland ^a   Schaupp, Lukas ^b   Ellmerer, Martin ^b   Korsatko, Stefan ^b   Kondepati, Venkata R ^c   Heise, H Michael ^c   Wilinska, Malgorzata E ^d   Hovorka, Roman ^d   Pieber, Thomas R ^a,b  

^a JOANNEUM RESEARCH   (Austria)

^b MEDICAL UNIVERSITY OF GRAZ   (Austria)

^c LEIBNIZ INSTITUT FÜR ANALYTISCHE WISSENSCHAFTEN ISAS E V   (Germany)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

CLINICIP; MPC algorithm; Spectroscopic glucose sensor; Tight glycemic control; Vascular microdialysis

Indexed keywords

ANTIDIABETIC AGENT; INSULIN;

ADULT; ALGORITHM; ARTICLE; BLOOD; BLOOD ANALYSIS; BLOOD VESSEL; CHEMISTRY; CLINICAL TRIAL; FEASIBILITY STUDY; FEMALE; GENETIC PROCEDURES; GLUCOSE BLOOD LEVEL; HUMAN; INFRARED SPECTROPHOTOMETRY; INSTRUMENTATION; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN INFUSION; INTENSIVE CARE UNIT; MALE; METABOLISM; METHODOLOGY; MICRODIALYSIS; MIDDLE AGED; MONITORING; PROGNOSIS; STATISTICAL MODEL; UTILIZATION REVIEW;

ADULT; ALGORITHMS; BIOSENSING TECHNIQUES; BLOOD CHEMICAL ANALYSIS; BLOOD GLUCOSE; BLOOD VESSELS; DIABETES MELLITUS, TYPE 1; FEASIBILITY STUDIES; FEMALE; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN; INSULIN INFUSION SYSTEMS; INTENSIVE CARE UNITS; MALE; MICRODIALYSIS; MIDDLE AGED; MODELS, STATISTICAL; MONITORING, PHYSIOLOGIC; PROGNOSIS; SPECTROPHOTOMETRY, INFRARED; YOUNG ADULT;

EID: 84855373369     PISSN: None     EISSN: 19322968     Source Type: Journal    
DOI: 10.1177/193229681100500412     Document Type: Article

References (19)

1. Van den Berghe G, Wouters P, Weekers F, Verwaest C, Bruyninckx F, Schetz M, Vlasselaers D, Ferdinande P, Lauwers P, Bouillon R. Intensive insulin therapy in the critically ill patients. N Engl J Med. 2001;345(19):1359-67.
2. Keenan DB, Mastrototaro JJ, Voskanyan G, Steil GM. Delays in minimally invasive continuous glucose monitoring devices: a review of current technology. J Diabetes Sci Technol. 2009;3(5):1207-14.
3. Vlasselaers D, Schaupp L, Van den Heuvel I, Mader J, Bodenlenz M, Suppan M, Wouters P, Ellmerer M, Van den Berghe G. Monitoring blood glucose with microdialysis of interstitial fluid in critically ill children. Clin Chem. 2007;53(3):536-7. (Pubitemid 46447956)
4. Feichtner F, Schaller R, Fercher A, Ratzer M, Ellmerer M, Plank J, Krause B, Pieber T, Schaupp L. Microdialysis based device for continuous extravascular monitoring of blood glucose. Biomed Microdevices. 2010;12(3):399-407.
5. Heise HM, Damm U, Bodenlenz M, Kondepati VR, Köhler G, Ellmerer M. Bed-side monitoring of subcutaneous interstitial glucose in healthy volunteers using microdialysis and infrared spectrometry. J Biomed Opt. 2007;12(2):024004.
6. Heise HM, Kondepati VR, Damm U, Licht M, Feichtner F, Mader JK, Ellmerer M. Microdialysis based monitoring of subcutaneous interstitial and venous blood glucose in type 1 diabetic subjects by mid-infrared spectrometry for intensive insulin therapy. SPIE Proc. 2008;6863:686308.
7. Hovorka R, Allen JM, Elleri D, Chassin LJ, Harris J, Xing D, Kollman C, Hovorka T, Larsen AM, Nodale M, De Palma A, Wilinska ME, Acerini CL, Dunger DB. Manual closed-loop insulin delivery in children and adolescents with type 1 diabetes: a phase 2 randomised crossover trial. Lancet. 2010;375(9716):743-51.
8. Plank J, Blaha J, Cordingley J, Wilinska ME, Chassin LJ, Morgan C, Squire S, Haluzik M, Kremen J, Svacina S, Toller W, Plasnik A, Ellmerer M, Hovorka R, Pieber TR. Multicentric, randomized, controlled trial to evaluate blood glucose control by the model predictive control algorithm versus routine glucose management protocols in intensive care unit patients. Diabetes Care. 2006;29(2):271-6. (Pubitemid 44106503)
9. Magarian P, Sterling B. Plasma-generating glucose monitor accuracy demonstrated in an animal model. J Diabetes Sci Technol. 2009;3(6):1411-8.
10. Bequette BW. A critical assessment of algorithms and challenges in the development of a closed-loop artificial pancreas. Diabetes Technol Ther. 2005;7(1):28-47. (Pubitemid 40354574)
11. Hovorka R, Canonico V, Chassin LJ, Haueter U, Massi-Benedetti M, Federici MO, Pieber TR, Schaller HC, Schaupp L, Vering T, Wilinska ME. Nonlinear model predictive control of glucose concentration in subjects with type 1 diabetes. Physiol Meas. 2004;25(4):905-20 (Pubitemid 39121173)
12. Hovorka R, Chassin LJ Canonico V, Akwi JA, Federici MO, Massi-Benedetti M, Hutzli I, Zaugg C, Kaufmann H, Both M, Vering T, Schaller HC, Schaupp L, Bodenlenz M, Pieber TR. Closing the loop: the ADICOL experience. Diabetes Technol Ther. 2004;6(3):307-18 (Pubitemid 38821615)
13. Kulnik R, Plank J, Pachler C, Wilinska ME, Groselj-Strele A, Röthlein D, Wufka M, Kachel N, Smolle KH, Perl S, Pieber TR, Hovorka R, Ellmerer M. Evaluation of implementation of a fully automated algorithm (enhanced model predictive control) in an interacting infusion pump system for establishment of tight glycemic control in medical intensive care unit patients. J Diabetes Sci Technol. 2008;2(6):963-70.
14. Vogelzang M, van der Horst IC, Nijsten MW. Hyperglycaemic index as a tool to assess glucose control: a retrospective study. Critical Care. 2004;8(3):R122-7.
15. Chassin LJ, Wilinska ME, Hovorka R. Grading system to assess clinical performance of closed-loop glucose control. Diabetes Technol Ther. 2005;7(1):72-82. (Pubitemid 40354577)
16. Ellmerer M, Haluzik M, Blaha J, Kremen J, Svacina S, Toller W, Mader J, Schaupp L, Plank J, Pieber T. Clinical evaluation of alternative site glucose measurements in patients after major cardiac surgery. Diabetes Care. 2006;29(6):1275-81. (Pubitemid 44125922)
17. Weinzimer SA, Steil GM, Swan KL, Dziura J, Kurtz N, Tamborlane WV. Fully automated closed-loop insulin delivery versus semiautomated hybrid control in pediatric patients with type 1 diabetes using an artificial pancreas. Diabetes Care. 2008;31(5):934-9.
18. Renard E, Place J, Cantwell M, Chevassus H, Palerm CC. Closed-loop insulin delivery using a subcutaneous glucose sensor and intraperitoneal insulin delivery: feasibility study testing a new model for the artificial pancreas. Diabetes Care. 2010;33(1):121-7.
19. Kovatchev B, Cobelli C, Renard E, Anderson S, Breton M, Patek S, Clarke W, Bruttomesso D, Maran A, Costa S, Avogaro A, Dalla Man C, Facchinetti A, Magni L, De Nicolao G, Place J, Farret A. Multinational study of subcutaneous model-predictive closed-loop control in type 1 diabetes mellitus: summary of the results. J Diabetes Sci Technol. 2010;4(6):1374-81.