Closed-loop insulin delivery using a subcutaneous glucose sensor and intraperitoneal insulin delivery: Feasibility study testing a new model for the artificial pancreas

Diabetes Care

Volumn 33, Issue 1, 2010, Pages 121-127

  Renard, Eric ^a   Place, Jerome ^a   Cantwell, Martin ^b   Chevassus, Hugues ^a   Palerm, Cesar C ^b  

^a MONTPELLIER UNIVERSITY HOSPITAL   (France)

^b MEDTRONIC INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN;

ADULT; AGED; ARTICLE; ARTIFICIAL PANCREAS; BLOOD GLUCOSE MONITORING; CLINICAL ARTICLE; CLOSED LOOP INTRAPERITONEAL INSULIN INFUSION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; FEASIBILITY STUDY; FEMALE; GLUCOSE BLOOD LEVEL; GLYCEMIC CONTROL; HUMAN; INSULIN BLOOD LEVEL; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN PUMP; MALE; SENSOR; SUBCUTANEOUS GLUCOSE SENSOR;

ADOLESCENT; ADULT; AGED; BIOSENSING TECHNIQUES; BLOOD GLUCOSE; FEMALE; HUMANS; HYPOGLYCEMIC AGENTS; INFUSION PUMPS, IMPLANTABLE; INFUSIONS, PARENTERAL; INSULIN; MALE; MIDDLE AGED; MONITORING, AMBULATORY; PANCREAS, ARTIFICIAL; YOUNG ADULT;

EID: 74249093844     PISSN: 01495992     EISSN: 19355548     Source Type: Journal    
DOI: 10.2337/dc09-1080     Document Type: Article

References (25)

1. The Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 1993;329:977-986
2. Nathan DM, Cleary PA, Backlund JY, Genuth SM, Lachin JM, Orchard TJ, Raskin P, Zinman B, Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study Research Group. Intensive diabetes management and cardiovascular disease in patients with type 1 diabetes. N Engl J Med 2005;353:2643-2653
3. Renard E. Implantable closed-loop glucose-sensing and insulin delivery: the future for insulin pump therapy. Curr Opin Pharmacol 2002;2:708-716
4. The Diabetes Control and Complications Trial Research Group. Hypoglycemia in the Diabetes Control and Complications Trial. Diabetes 1997;46:271-286
5. Albisser AM, Leibel BS, Ewart TG, Davidovac Z, Botz CK, Zingg W, Schipper H, Gander R. Clinical control of diabetes by the artificial pancreas. Diabetes 1974;23:397-404
6. Mirouze J, Selam JL, Pham TC, Cavadore D. Evaluation of exogenous insulin homeostasis by the artificial pancreas in insulin-dependent diabetes. Diabetologia 1977;13:273-278
7. Jaremko J, Rorstad O. Advances toward the implantable artificial pancreas for treatment of diabetes. Diabetes Care 1998;21:444-450
8. Clemens AH, Chang PH, Myers RW. The development of Biostator, a glucose controlled insulin infusion system (GCIIS). Horm Metab Res 1977;(Suppl. 7):23-33
9. Hirsch IB, Abelseth J, Bode BW, Fischer JS, Kaufman FR, Mastrototaro J, Parkin CG, Wolpert HA, Buckingham BA. Sensor-augmented insulin pump therapy: results of the first randomized treat-to-target study. Diabetes Technol Ther 2008;10:377-383
10. Maia FF, Araú jo LR. Efficacy of continuous glucose monitoring system (CGMS) to detect postprandial hyperglycemia and unrecognized hypoglycemia in type 1 diabetic patients. Diabetes Res Clin Pract 2007;75:30-34
11. Mastrototaro J, Shin J, Marcus A, Sulur G, STAR 1 Clinical Trial Investigators. The accuracy and efficacy of real-time continuous glucose monitoring sensor in patients with type 1 diabetes. Diabetes Technol Ther 2008;10:385-390
12. Hovorka R. Continuous glucose monitoring and closed-loop systems. Diabet Med 2006;23:1-12
13. Steil GM, Rebrin K, Darwin C, Hariri F, Saad MF. Feasibility of automating insulin delivery for the treatment of type 1 diabetes. Diabetes 2006;55:3344-3350
14. Renard E, Costalat G, Chevassus H, Bringer J. Closed loop insulin delivery using implanted insulin pumps and sensors in type 1 diabetic patients. Diabetes Res Clin Pract 2006;74(Suppl. 2): S173-S177
15. Steil GM, Panteleon AE, Rebrin K. Closed-loop insulin delivery - the path to physiological glucose control. Adv Drug Deliv Rev 2004;56:125-144
16. Weinzimer SA, Steil GM, Swan KL, Dziura J, Kurtz N, Tamborlane WV. Fully automated closed-loop insulin delivery versus semiautomated hybrid control in pediatric patients with type 1 diabetes using an artificial pancreas. Diabetes Care 2008;31:934-939
17. Renard E, Schaepelynck-Bélicar P, EVADIAC Group. Implantable insulin pumps. A position statement about their clinical use. Diabetes Metab 2007;33:158-166
18. Renard E, Costalat G, Chevassus H, Bringer J. Artificial β-cell: clinical experience toward an implantable closed-loop insulin delivery system. Diabetes Metab 2006;32(5 Pt. 2):497-502
19. Palmer JP, Asplin CM, Clemons P, Lyen K, Tatpati O, Raghu PK, Paquette TL. Insulin antibodies in insulin-dependent diabetes before treatment. Science 1983;222:1337-1339
20. Steil GM, Rebrin K, Janowski R, Darwin C, Saad MF. Modeling β-cell insulin secretion - implications for closed-loop glucose homeostasis. Diabetes Technol Ther 2003;5:953-964
21. Palerm CC: Physiologic insulin delivery with insulin feedback: a control systems perspective. In Proceedings of the 7th IFAC Symposium on Modeling and Control in Biomedical Systems, Aalborg, Denmark, 2009, Laxenburg, Austria, International Federation of Automatic Control, p. 31-36
22. Monnier L, Mas E, Ginet C, Michel F, Villon L, Cristol JP, Colette C. Activation of oxidative stress by acute glucose fluctuations compared with sustained chronic hyperglycemia in patients with type 2 diabetes. JAMA 2006;295:1681-1687
23. Cryer PE. Mechanisms of hypoglycemia-associated autonomic failure and its component syndromes in diabetes. Diabetes 2005;54:3592-3601
24. Ahrén B, Holst JJ. The cephalic insulin response to meal ingestion in humans is dependent on both cholinergic and noncholinergic mechanisms and is important for postprandial glycemia. Diabetes 2001;50:1030-1038
25. Festa A, Williams K, Hanley AJ, Haffner SM. β-Cell dysfunction in subjects with impaired glucose tolerance and early type 2 diabetes: comparison of surrogate markers with first-phase insulin secretion from an intravenous glucose tolerance test. Diabetes 2008;57:1638-1644