Are immunoglobulin a anti-gliadin antibodies helpful in diagnosing coeliac disease in children younger than 2 years?

Journal of Pediatric Gastroenterology and Nutrition

Volumn 54, Issue 1, 2012, Pages 110-112

  Foucher, Barbara ^a   Johanet, Catherine ^b   Jégo Desplat, Sophie ^b   Sanmarco, Marielle ^b   Dubucquoi, Sylvain ^b   Fily Nalewajk, Sandrine ^c   Olsson, Nils Olivier ^b   Lakomy, Daniela ^b   Escande, Andrée ^b   Chrétien, Pascale ^b   Fortenfant, Françoise ^b   Chevailler, Alain ^b   André, Chantal ^b   Goetz, Joëlle ^b   Humbel, René Louis ^b   Monier, Jean Claude ^b   Sibilia, Jean ^b   Taillefer, Marie France ^b   Abreu, Isabelle ^b   Fabien, Nicole ^a  

^a CENTRE HOSPITALIER LYON SUD   (France)

^b Groupe d Etude de l Auto Immunité GEAI   (France)

^c LILLE UNIVERSITY HOSPITAL   (France)

Author keywords

celiac disease; IgA anti endomysium antibodies; IgA anti transglutaminase antibodies; IgA antigliadin antibodies

Indexed keywords

ENDOMYSIUM ANTIBODY; GLIADIN ANTIBODY; IMMUNOGLOBULIN A ANTIBODY; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE ANTIBODY;

ABDOMINAL PAIN; ANTIBODY DETECTION; ARTICLE; CELIAC DISEASE; CHILD; CONSTIPATION; DIAGNOSTIC VALUE; DIARRHEA; DUODENUM BIOPSY; FEMALE; GASTRITIS; GROWTH RETARDATION; HUMAN; INTESTINE VILLUS ATROPHY; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PRIORITY JOURNAL;

ANTIBODIES, ANTI-IDIOTYPIC; BIOPSY; CELIAC DISEASE; CHILD, PRESCHOOL; DUODENUM; FEMALE; GLIADIN; HUMANS; IMMUNOGLOBULIN A; INCIDENCE; INFANT; MALE; TRANSGLUTAMINASES;

EID: 84855356584     PISSN: 02772116     EISSN: 15364801     Source Type: Journal    
DOI: 10.1097/MPG.0b013e31823255c9     Document Type: Article

References (24)

1. Fasano A, Catassi C. Current approaches to diagnosis and treatment of celiac disease: An evolving spectrum. Gastroenterology 2001;120: 636-51. (Pubitemid 32171637)
2. Hill ID, Dirks MH, Liptak GS, et al. Guideline for the diagnosis and treatment of celiac disease in children: Recommendations of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition. J Pediatr Gastroenterol Nutr 2005;40:1-19. (Pubitemid 40180049)
3. Norris JM, Barriga K, Hoffenberg EJ, et al. Risk of celiac disease autoimmunity and timing of gluten introduction in the diet of infants at increased risk of disease. JAMA 2005;293:2343-51. (Pubitemid 40676756)
4. Fasano A, Catassi C. Coeliac disease in children. Best Pract Res Clin Gastroenterol 2005;19:467-78. (Pubitemid 40753766)
5. van Heel DA, West J. Recent advances in coeliac disease. Gut 2006;55:1037-46. (Pubitemid 43962618)
6. Ravikumara M, Tuthill DP, Jenkins HR. The changing clinical presentation of coeliac disease. Arch Dis Child 2006;91:969-71. (Pubitemid 44863131)
7. Ciclitira PJ, JohnsonMW, Dewar DH, et al. The pathogenesis of coeliac disease. Mol Aspects Med 2005;26:421-58. (Pubitemid 41728297)
8. Stern M. Comparative evaluation of serologic tests for celiac disease: A European initiative toward standardization. J Pediatr Gastroenterol Nutr 2000;31:513-9.
9. Rostom A, Dube C, Cranney A, et al. The diagnostic accuracy of serologic tests for celiac disease: A systematic review. Gastroenterology 2005;128:S38-46. (Pubitemid 40460820)
10. Sulkanen S, Halttunen T, Laurila K, et al. Tissue transglutaminase autoantibody enzyme-linked immunosorbent assay in detecting celiac disease. Gastroenterology 1998;115:1322-8. (Pubitemid 28545980)
11. Horvath K, Hill ID. Anti-tissue transglutaminase antibody as the first line screening for celiac disease: good-bye antigliadin tests? Am J Gastroenterol 2002;97:2702-4. (Pubitemid 35265417)
12. NIH Consensus Development Conference on Celiac Disease. Consensus development conference statement. http://consensus.nih.gov/2004/ 2004celiacdisease118html.htm. Accessed November 25, 2011.
13. Ghedira I, Sghiri R, Ayadi A, et al. Anti-endomysium, anti-reticulin and anti-gliadin antibodies, value in the diagnosis of celiac disease in the child. Pathol Biol (Paris) 2001;49:47-52. (Pubitemid 32174330)
14. Lagerqvist C, Dahlbom I, Hansson T, et al. Antigliadin immunoglobulin A best in finding celiac disease in children younger than 18 months of age. J Pediatr Gastroenterol Nutr 2008;47:428-35.
15. Burgin-Wolff A, Gaze H, Hadziselimovic F, et al. Antigliadin and antiendomysium antibody determination for coeliac disease. Arch Dis Child 1991;66:941-7.
16. Maglio M, Tosco A, Paparo F, et al. Serum and intestinal celiac diseaseassociated antibodies in children with celiac disease younger than 2 years of age. J Pediatr Gastroenterol Nutr 2010;50:43-8.
17. Holding S, Abuzakouk M, Dore PC. Antigliadin antibody testing for coeliac disease in children under 3 years of age is unhelpful. J Clin Pathol 2009;62:766-7.
18. Revised criteria for diagnosis of coeliac disease. Report of Working Group of European Society of Paediatric Gastroenterology and Nutrition. Arch Dis Child 1990;65:909-11.
19. Hansson T, Dannaeus A, Kraaz W, et al. Production of antibodies to gliadin by peripheral blood lymphocytes in children with celiac disease: The use of an enzyme-linked immunospot technique for screening and follow-up. Pediatr Res 1997;41:554-9. (Pubitemid 27147873)
20. Marzari R, Sblattero D, Florian F, et al. Molecular dissection of the tissue transglutaminase autoantibody response in celiac disease. J Immunol 2001;166:4170-6. (Pubitemid 32224950)
21. Bonamico M, Ballati G, Mariani P, et al. Screening for coeliac disease: The meaning of low titers of anti-gliadin antibodies (AGA) in noncoeliac children. Eur J Epidemiol 1997;13:55-9. (Pubitemid 27105182)
22. Baudon JJ, Johanet C, Absalon YB, et al. Diagnosing celiac disease: A comparison of human tissue transglutaminase antibodies with antigliadin and antiendomysium antibodies. Arch Pediatr Adolesc Med 2004;158:584-8. (Pubitemid 38720491)
23. Simell S, Hoppu S, Hekkala A, et al. Fate of five celiac diseaseassociated antibodies during normal diet in genetically at-risk children observed from birth in a natural history study. Am J Gastroenterol 2007;102:2026-35. (Pubitemid 47301530)
24. Catassi C, Fasano A. Celiac disease diagnosis: Simple rules are better than complicated algorithms. Am J Med 2010;123:691-3.