J7, a methyl jasmonate derivative, enhances TRAIL-mediated apoptosis through up-regulation of reactive oxygen species generation in human hepatoma HepG2 cells

Toxicology in Vitro

Volumn 26, Issue 1, 2012, Pages 86-93

  Park, Cheol ^a   Jin, Cheng Yun ^b   Hwang, Hye Jin ^c   Kim, Gi Young ^d,e   Jung, Jee H ^f   Kim, Wun Jae ^e   Yoo, Young Hyun ^g   Choi, Yung Hyun ^a,d,e  

^a Dong Eui University   (South Korea)

^b Blue Bio Industry Regional Innovation Center   (South Korea)

^c Dong Eui University   (South Korea)

^d Jeju National University   (South Korea)

^e Chungbuk National University College of Medicine   (South Korea)

^f Pusan National University   (South Korea)

^g Dong A University College of Medicine   (South Korea)

Author keywords

Apoptosis; HepG2; J7; ROS; TRAIL

Indexed keywords

ACETYLCYSTEINE; CASPASE; CASPASE INHIBITOR; J7; JASMONIC ACID; PHOSPHOLIPASE; PHOSPHOLIPASE GAMMA 1; POLY(ADENOSINE DIPHOSPHATE RIBOSE); PROTEIN BCL XL; PROTEIN BID; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG; X LINKED INHIBITOR OF APOPTOSIS;

APOPTOSIS; ARTICLE; CELL COUNT; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; DRUG EFFICACY; DRUG SAFETY; DRUG SENSITIZATION; ENZYME ACTIVATION; HEPATOMA CELL; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; PROTEIN CLEAVAGE; SIGNAL TRANSDUCTION; UPREGULATION;

ACETIC ACIDS; APOPTOSIS; BCL-X PROTEIN; CARCINOMA, HEPATOCELLULAR; CASPASES; CELL LINE, TUMOR; CYCLOPENTANES; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; LIVER NEOPLASMS; OXYLIPINS; REACTIVE OXYGEN SPECIES; TNF-RELATED APOPTOSIS-INDUCING LIGAND; UP-REGULATION; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 84855353202     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2011.10.016     Document Type: Article

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