Trypanosoma brucei AP endonuclease 1 has a major role in the repair of abasic sites and protection against DNA-damaging agents

DNA Repair

Volumn 11, Issue 1, 2012, Pages 53-64

  Charret, Karen S ^a,b   Requena, Cristina E ^a   Castillo Acosta, Víctor M ^a   Ruiz Pérez, Luis M ^a   González Pacanowska, Dolores ^a   Vidal, Antonio E ^a  

^a INSTITUTO DE PARASITOLOGÍA Y BIOMEDICINA LÓPEZ NEYRA   (Spain)

^b INSTITUTO OSWALDO CRUZ   (Brazil)

Author keywords

AP endonuclease; AP site; APE1; BER; Strand break; Trypanosoma brucei

Indexed keywords

AP ENDONUCLEASE 1; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; GENOMIC DNA; METHOTREXATE; NITRIC OXIDE; PHLEOMYCIN; UNCLASSIFIED DRUG;

ARTICLE; CELL FUNCTION; CELL LINE; CELL TYPE; CELL VIABILITY; CORRELATION ANALYSIS; DNA REPAIR; DNA STRAND BREAKAGE; GENETIC SUSCEPTIBILITY; HOST; HYPERSENSITIVITY; IMMUNITY; IN VITRO STUDY; MAMMAL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; TRYPANOSOMA BRUCEI;

ALKYLATION; ANIMALS; BASE SEQUENCE; CELL EXTRACTS; CELL PROLIFERATION; CYTOPROTECTION; DNA DAMAGE; DNA REPAIR; DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE; ENZYME ACTIVATION; GENOME; HYDROXYLAMINES; INTRACELLULAR SPACE; LIFE CYCLE STAGES; METHOTREXATE; MOLECULAR SEQUENCE DATA; MUTAGENS; NITRIC OXIDE; PROTEIN TRANSPORT; TRYPANOSOMA BRUCEI BRUCEI;

BACTERIA (MICROORGANISMS); MAMMALIA; PROTOZOA; TRYPANOSOMA BRUCEI;

EID: 84855346937     PISSN: 15687864     EISSN: 15687856     Source Type: Journal    
DOI: 10.1016/j.dnarep.2011.10.006     Document Type: Article

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