Factors predicting oncologic outcomes in patients with fewer than 12 lymph nodes retrieved after curative resection for colon cancer

Journal of Surgical Oncology

Volumn 105, Issue 2, 2012, Pages 125-129

  Huh, Jung Wook ^a   Kim, Chang Hyun ^a   Kim, Hyeong Rok ^a   Kim, Young Jin ^a  

^a Chonnam National University   (South Korea)

Author keywords

colon cancer; lymph node ratio; prognosis

Indexed keywords

CARCINOEMBRYONIC ANTIGEN;

ADULT; AGED; ARTICLE; CANCER CHEMOTHERAPY; CANCER RECURRENCE; CANCER RISK; CANCER STAGING; CANCER SURVIVAL; COLON CANCER; DISEASE FREE SURVIVAL; FEMALE; HUMAN; LONG TERM SURVIVAL; LYMPHADENECTOMY; MALE; OUTCOME ASSESSMENT; OVERALL SURVIVAL; POSTOPERATIVE CARE; PREOPERATIVE PERIOD; PRIORITY JOURNAL; PROGNOSIS; PROSPECTIVE STUDY;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; CARCINOEMBRYONIC ANTIGEN; COLONIC NEOPLASMS; FEMALE; FOLLOW-UP STUDIES; HUMANS; LYMPH NODES; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NEOPLASM INVASIVENESS; NEOPLASM RECURRENCE, LOCAL; NEOPLASM STAGING; PROGNOSIS; PROSPECTIVE STUDIES; SURVIVAL RATE;

EID: 84855340978     PISSN: 00224790     EISSN: 10969098     Source Type: Journal    
DOI: 10.1002/jso.22072     Document Type: Article

References (28)

1. Nelson H, Petrelli N, Carlin A, et al.: Guidelines 2000 for colon and rectal cancer surgery. J Natl Cancer Inst 2001; 93: 583-596. (Pubitemid 32409626)
2. Le Voyer TE, Sigurdson ER, Hanlon AL, et al.: Colon cancer survival is associated with increasing number of lymph nodes analyzed: A secondary survey of intergroup trial INT-0089. J Clin Oncol 2003; 21: 2912-2919. (Pubitemid 46621841)
3. Prandi M, Lionetto R, Bini A, et al.: Prognostic evaluation of stage B colon cancer patients is improved by an adequate lymphadenectomy: Results of a secondary analysis of a large scale adjuvant trial. Ann Surg 2002; 235: 458-463. (Pubitemid 34258343)
4. Huh JW, Kim YJ, Kim HR,: Ratio of metastatic to resected lymph nodes as a prognostic factor in node-positive colorectal cancer. Ann Surg Oncol 2010; 17: 2640-2646.
5. Peschaud F, Benoist S, Julie C, et al.: The ratio of metastatic to examined lymph nodes is a powerful independent prognostic factor in rectal cancer. Ann Surg 2008; 248: 1067-1073.
6. Wang J, Hassett JM, Dayton MT, et al.: Lymph node ratio: Role in the staging of node-positive colon cancer. Ann Surg Oncol 2008; 15: 1600-1608.
7. Vaccaro CA, Im V, Rossi GL, et al.: Lymph node ratio as prognosis factor for colon cancer treated by colorectal surgeons. Dis Colon Rectum 2009; 52: 1244-1250.
8. Schumacher P, Dineen S, Barnett C, Jr., et al.: The metastatic lymph node ratio predicts survival in colon cancer. Am J Surg 2007; 194: 827-831.
9. Berger AC, Sigurdson ER, LeVoyer T, et al.: Colon cancer survival is associated with decreasing ratio of metastatic to examined lymph nodes. J Clin Oncol 2005; 23: 8706-8712. (Pubitemid 46211514)
10. Swanson RS, Compton CC, Stewart AK, et al.: The prognosis of T3N0 colon cancer is dependent on the number of lymph nodes examined. Ann Surg Oncol 2003; 10: 65-71.
11. Tepper JE, O'Connell MJ, Niedzwiecki D, et al.: Impact of number of nodes retrieved on outcome in patients with rectal cancer. J Clin Oncol 2001; 19: 157-163. (Pubitemid 32063492)
12. Wong JH, Severino R, Honnebier MB, et al.: Number of nodes examined and staging accuracy in colorectal carcinoma. J Clin Oncol 1999; 17: 2896-2900. (Pubitemid 29415250)
13. Chang GJ, Rodriguez-Bigas MA, Skibber JM, et al.: Lymph node evaluation and survival after curative resection of colon cancer: Systematic review. J Natl Cancer Inst 2007; 99: 433-441. (Pubitemid 47073566)
14. Johnson PM, Porter GA, Ricciardi R, et al.: Increasing negative lymph node count is independently associated with improved long-term survival in stage IIIB and IIIC colon cancer. J Clin Oncol 2006; 24: 3570-3575. (Pubitemid 46630528)
15. Tsikitis VL, Larson DL, Wolff BG, et al.: Survival in stage III colon cancer is independent of the total number of lymph nodes retrieved. J Am Coll Surg 2009; 208: 42-47.
16. Wong SL, Ji H, Hollenbeck BK, et al.: Hospital lymph node examination rates and survival after resection for colon cancer. JAMA 2007; 298: 2149-2154. (Pubitemid 350106653)
17. Schrag D, Panageas KS, Riedel E, et al.: Surgeon volume compared to hospital volume as a predictor of outcome following primary colon cancer resection. J Surg Oncol 2003; 83: 68-78. (Pubitemid 36667413)
18. Johnson PM, Malatjalian D, Porter GA,: Adequacy of nodal harvest in colorectal cancer: A consecutive cohort study. J Gastrointest Surg 2002; 6: 883-888.
19. Baxter NN, Virnig DJ, Rothenberger DA, et al.: Lymph node evaluation in colorectal cancer patients: A population-based study. J Natl Cancer Inst 2005; 97: 219-225. (Pubitemid 40277372)
20. Namm J, Ng M, Roy-Chowdhury S, et al.: Quantitating the impact of stage migration on staging accuracy in colorectal cancer. J Am Coll Surg 2008; 207: 882-887.
21. Tsai HL, Yeh YS, Yu FJ, et al.: Predicting factors of postoperative relapse in T2-4N0M0 colorectal cancer patients via harvesting a minimum of 12 lymph nodes. Int J Colorectal Dis 2009; 24: 177-183.
22. Monig SP, Baldus SE, Zirbes TK, et al.: Lymph node size and metastatic infiltration in colon cancer. Ann Surg Oncol 1999; 6: 579-581. (Pubitemid 29428798)
23. Herrera-Ornelas L, Justiniano J, Castillo N, et al.: Metastases in small lymph nodes from colon cancer. Arch Surg 1987; 122: 1253-1256. (Pubitemid 18021277)
24. Wood TF, Saha S, Morton DL, et al.: Validation of lymphatic mapping in colorectal cancer: In vivo, ex vivo, and laparoscopic techniques. Ann Surg Oncol 2001; 8: 150-157. (Pubitemid 32199412)
25. Blenkinsopp WK, Stewart-Brown S, Blesovsky L, et al.: Histopathology reporting in large bowel cancer. J Clin Pathol 1981; 34: 509-513. (Pubitemid 11063958)
26. Huh JW, Oh BR, Kim HR, et al.: Preoperative carcinoembryonic antigen level as an independent prognostic factor in potentially curative colon cancer. J Surg Oncol 2010; 101: 396-400.
27. Takagawa R, Fujii S, Ohta M, et al.: Preoperative serum carcinoembryonic antigen level as a predictive factor of recurrence after curative resection of colorectal cancer. Ann Surg Oncol 2008; 15: 3433-3439.
28. Kim KH, Oh JH, Choi HS, et al.: Pretreatment serum CEA as a prognostic factor for rectal cancer treated with preoperative chemoradiotherapy. J Korean Soc Coloproctol 2010; 26: 39-44.