Ratio of metastatic to resected Lymph nodes as a prognostic factor in node-positive colorectal cancer

Annals of Surgical Oncology

Volumn 17, Issue 10, 2010, Pages 2640-2646

  Huh, Jung Wook ^a   Kim, Young Jin ^a   Kim, Hyeong Rok ^a  

^a Chonnam National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CANCER ADJUVANT THERAPY; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER SURGERY; CANCER SURVIVAL; CLINICAL ASSESSMENT; COLON RESECTION; COLORECTAL CARCINOMA; DISEASE FREE SURVIVAL; FEMALE; FOLLOW UP; HUMAN; LYMPH NODE DISSECTION; LYMPH NODE METASTASIS; LYMPHADENECTOMY; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; NODE POSITIVE COLORECTAL CANCER; OVERALL SURVIVAL; PROGNOSIS; RECTUM CANCER; RETROSPECTIVE STUDY; SURVIVAL RATE;

ADENOCARCINOMA, MUCINOUS; ADULT; AGED; AGED, 80 AND OVER; COLORECTAL NEOPLASMS; FEMALE; HUMANS; LYMPH NODE EXCISION; LYMPH NODES; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NEOPLASM INVASIVENESS; PROGNOSIS; SURVIVAL RATE;

EID: 78049483070     PISSN: 10689265     EISSN: 15344681     Source Type: Journal    
DOI: 10.1245/s10434-010-1015-2     Document Type: Article

References (22)

1. RS Swanson CC Compton AK Stewart KI Bland 2003 The prognosis of T3N0 colon cancer is dependent on the number of lymph nodes examined Ann Surg Oncol 10 65 71 10.1245/ASO.2003.03.058 12513963
2. TE Le Voyer ER Sigurdson AL Hanlon, et al. 2003 Colon cancer survival is associated with increasing number of lymph nodes analyzed: a secondary survey of intergroup trial INT-0089 J Clin Oncol 21 2912 2919 1:STN:280: DC%2BD3szltlersA%3D%3D 10.1200/JCO.2003.05.062 12885809
3. NE Joseph ER Sigurdson AL Hanlon, et al. 2003 Accuracy of determining nodal negativity in colorectal cancer on the basis of the number of nodes retrieved on resection Ann Surg Oncol 10 213 218 10.1245/ASO.2003.03.059 12679304
4. HL Tsai CY Lu JS Hsieh, et al. 2007 The prognostic significance of total lymph node harvest in patients with T2-4N0M0 colorectal cancer J Gastrointest Surg 11 660 665 10.1007/s11605-007-0119-x 17468927
5. PM Johnson GA Porter R Ricciardi NN Baxter 2006 Increasing negative lymph node count is independently associated with improved long-term survival in stage IIIB and IIIC colon cancer J Clin Oncol 24 3570 3575 10.1200/JCO.2006.06. 8866 16877723
6. S George J Primrose R Talbot, et al. 2006 Will Rogers revisited: prospective observational study of survival of 3592 patients with colorectal cancer according to number of nodes examined by pathologists Br J Cancer 95 841 847 1:STN:280:DC%2BD28rosVGhtQ%3D%3D 10.1038/sj.bjc.6603352 16969342
7. L Sarli G Bader D Iusco, et al. 2005 Number of lymph nodes examined and prognosis of TNM stage II colorectal cancer Eur J Cancer 41 272 279 10.1016/j.ejca.2004.10.010 15661553
8. SJ Moug JD Saldanha JR McGregor M Balsitis RH Diament 2009 Positive lymph node retrieval ratio optimises patient staging in colorectal cancer Br J Cancer 100 1530 1533 1:STN:280:DC%2BD1MzjvFeltg%3D%3D 10.1038/sj.bjc.6605049 19401684
9. CA Vaccaro V Im GL Rossi, et al. 2009 Lymph node ratio as prognosis factor for colon cancer treated by colorectal surgeons Dis Colon Rectum 52 1244 1250 19571700
10. IJ Park GS Choi SH Jun 2009 Nodal stage of stage III colon cancer: the impact of metastatic lymph node ratio J Surg Oncol 100 240 243 10.1002/jso.21273 19330780
11. YS Kim JH Kim SM Yoon, et al. 2009 lymph node ratio as a prognostic factor in patients with stage III rectal cancer treated with total mesorectal excision followed by chemoradiotherapy Int J Radiat Oncol Biol Phys 74 796 802 19289261
12. F Peschaud S Benoist C Julie, et al. 2008 The ratio of metastatic to examined lymph nodes is a powerful independent prognostic factor in rectal cancer Ann Surg 248 1067 1073 10.1097/SLA.0b013e31818842ec 19092352
13. J Peng Y Xu Z Guan, et al. 2008 Prognostic significance of the metastatic lymph node ratio in node-positive rectal cancer Ann Surg Oncol 15 3118 3123 10.1245/s10434-008-0123-8 18769971
14. P Schumacher S Dineen C Barnett Jr J Fleming T Anthony 2007 The metastatic lymph node ratio predicts survival in colon cancer Am J Surg 194 827 831 10.1016/j.amjsurg.2007.08.030 18005779
15. HY Lee HJ Choi KJ Park, et al. 2007 Prognostic significance of metastatic lymph node ratio in node-positive colon carcinoma Ann Surg Oncol 14 1712 1717 10.1245/s10434-006-9322-3 17253102
16. AC Berger ER Sigurdson T LeVoyer, et al. 2005 Colon cancer survival is associated with decreasing ratio of metastatic to examined lymph nodes J Clin Oncol 23 8706 8712 10.1200/JCO.2005.02.8852 16314630
17. JW Huh HR Kim YJ Kim 2009 Proliferating cell nuclear antigen as a prognostic factor after total mesorectal excision of stage II-III rectal cancer Ann Surg Oncol 16 1494 1500 10.1245/s10434-009-0424-6 19267156
18. CC Thorn NP Woodcock N Scott, et al. 2004 What factors affect lymph node yield in surgery for rectal cancer? Colorectal Dis 6 356 361 1:STN:280:DC%2BD2cvjtVGrsQ%3D%3D 10.1111/j.1463-1318.2004.00670.x 15335370
19. J Wang JM Hassett MT Dayton MN Kulaylat 2008 Lymph node ratio: role in the staging of node-positive colon cancer Ann Surg Oncol 15 1600 1608 10.1245/s10434-007-9716-x 18327530
20. L Stocchi H Nelson DJ Sargent, et al. 2001 Impact of surgical and pathologic variables in rectal cancer: a United States community and cooperative group report. Lymph node ratio: role in the staging of node-positive colon cancer J Clin Oncol 19 3895 3902 1:STN:280:DC%2BD3Mrht1Sluw%3D%3D 11559727
21. JW Huh HR Kim 2009 Postoperative chemotherapy after neoadjuvant chemoradiation and surgery for rectal cancer: is it essential for patients with ypT0-2No? J Surg Oncol 100 387 391 1:CAS:528:DC%2BD1MXhtlSjt7nJ 10.1002/jso.21342 19582821
22. JF Bosset L Collette G Calais, et al. 2006 Chemotherapy with preoperative radiotherapy in rectal cancer N Engl J Med 355 1114 1123 1:CAS:528: DC%2BD28XpsFKkur8%3D 10.1056/NEJMoa060829 16971718