The design and inhibitory profile of new benzimidazole derivatives against triosephosphate isomerase from Trypanosoma cruzi: A problem of residue motility

Journal of Molecular Graphics and Modelling

Volumn 30, Issue , 2011, Pages 90-99

  Romo Mancillasa, Antonio ^a   Téllez Valenciab, Alfredo ^b   Yépez Muliac, Lilián ^c   Hernández Luisa, Francisco ^a   Hernández Camposa, Alicia ^a   Castillo, Rafael ^a  

^a UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^b UNIVERSIDAD JUÁREZ DEL ESTADO DE DURANGO   (Mexico)

^c INSTITUTO MEXICANO DEL SEGURO SOCIAL   (Mexico)

Author keywords

Benzimidazole; Docking; Homodimeric interface; Triosephosphate isomerase

Indexed keywords

DOCKING; MOLECULAR GRAPHICS; PHYSICAL CHEMISTRY;

BENZIMIDAZOLE DERIVATIVES; BENZIMIDAZOLES; DOCKING PROCEDURES; HYDROPHOBIC POCKETS; INHIBITORY ACTIVITY; INHIBITORY PROFILES; SELECTIVE INHIBITORS; TRIOSEPHOSPHATE ISOMERASE;

BINS;

BENZIMIDAZOLE DERIVATIVE; TRIOSEPHOSPHATE ISOMERASE;

ARTICLE; BINDING SITE; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; HYDROPHOBICITY; PRIORITY JOURNAL; TRYPANOSOMA CRUZI; VALIDATION STUDY;

TRYPANOSOMA CRUZI;

EID: 84855300442     PISSN: 10933263     EISSN: 18734243     Source Type: Journal    
DOI: 10.1016/j.jmgm.2011.06.009     Document Type: Article

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