Structural considerations for the rational design of selective anti-trypanosomal agents: The role of the aromatic clusters at the interface of triosephosphate isomerase dimer

Biochemical and Biophysical Research Communications

Volumn 328, Issue 4, 2005, Pages 922-928

  Espinoza Fonseca, L Michel ^a   Trujillo Ferrara, José G ^b  

^a Physics and Informatics   (Slovakia)

^b INSTITUTO POLITÉCNICO NACIONAL   (Mexico)

Author keywords

Benzothiazole; Chagas' disease; Docking; Triosephosphate isomerase inhibition

Indexed keywords

ANTITRYPANOSOMAL AGENT; AROMATIC COMPOUND; BENZOTHIAZOLE DERIVATIVE; DIMER; TRIOSEPHOSPHATE ISOMERASE;

ARTICLE; CALCULATION; COMPLEX FORMATION; COMPUTER PROGRAM; CONTROLLED STUDY; DRUG PROTEIN BINDING; HUMAN; HYPOTHESIS; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL;

EID: 13744258061     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.01.043     Document Type: Article

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