Diversity in the C3b convertase contact residues and tertiary structures of the staphylococcal complement inhibitor (SCIN) protein family

Journal of Biological Chemistry

Volumn 287, Issue 1, 2012, Pages 628-640

  Garcia, Brandon L ^a   Summers, Brady J ^a   Lin, Zhuoer ^b   Ramyar, Kasra X ^a   Ricklin, Daniel ^b   Kamath, Divya V ^a   Fu, Zheng Qing ^c   Lambris, John D ^b   Geisbrecht, Brian V ^a  

^a UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c ARGONNE NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE PROTEINS; COMPARATIVE ANALYSIS; COMPLEMENT SYSTEMS; ELECTROSTATIC POTENTIALS; HOT SPOT; INACTIVE MEMBER; INITIAL STRUCTURES; N-TERMINAL TRUNCATION; N-TERMINALS; PROTEIN FAMILY; S. AUREUS; STAPHYLOCOCCUS AUREUS; STRUCTURAL DEVIATIONS; TERTIARY STRUCTURES;

BACTERIA;

PROTEINS;

ARGININE; BACTERIAL PROTEIN; CLASSICAL COMPLEMENT PATHWAY C3 C5 CONVERTASE; COMPLEMENT COMPONENT C3B CONVERTASE; COMPLEMENT COMPONENT C3C CONVERTASE; COMPLEMENT FACTOR; COMPLEMENT INHIBITOR; MUTANT PROTEIN; STAPHYLOCOCCUS COMPLEMENT INHIBITOR; STAPHYLOCOCCUS COMPLEMENT INHIBITOR B; STAPHYLOCOCCUS COMPLEMENT INHIBITOR D; TYROSINE; UNCLASSIFIED DRUG;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ANTIBIOTIC RESISTANCE; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN TARGETING;

ANIMALS; BACTERIAL PROTEINS; COMPLEMENT C3-C5 CONVERTASES; COMPLEMENT C3B; COMPLEMENT C3C; CRYSTALLOGRAPHY, X-RAY; HUMANS; MODELS, MOLECULAR; PROTEIN STRUCTURE, TERTIARY; STAPHYLOCOCCUS AUREUS;

STAPHYLOCOCCUS AUREUS;

EID: 84855289555     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.298984     Document Type: Article

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