Human peripheral blood lymphocytes and fibroblasts as Notch3 expression models

Journal of Cellular Physiology

Volumn 227, Issue 4, 2012, Pages 1771-1775

  di Maio, Giuseppe ^a   Formichi, Patrizia ^a   Radi, Elena ^a   Bianchi, Silvia ^a   Onnis, Anna ^a   Tarquini, Ermelinda ^b   Leoncini, Lorenzo ^a   Federico, Antonio ^a  

^a UNIVERSITY OF SIENA   (Italy)

^b UNIVERSITY HOSPITAL OF SIENA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; NOTCH3 RECEPTOR;

ADULT; ARTICLE; BLOOD; CELL TYPE; FEMALE; FIBROBLAST; HUMAN; HUMAN CELL; LYMPHOCYTE; MALE; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ADULT; BASE SEQUENCE; BLOTTING, WESTERN; FEMALE; FIBROBLASTS; GENE EXPRESSION PROFILING; HUMANS; JURKAT CELLS; LYMPHOCYTES; MALE; MIDDLE AGED; MODELS, BIOLOGICAL; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, NOTCH; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 84855267108     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.22901     Document Type: Article

References (21)

1. Anastasi E, Campese AF, Bellavia D, Bulotta A, Balestri A, Pascucci M, Checquolo S, Gradini R, Lendahl U, Frati L, Gulino A, Di Mario U, Screpanti I. 2003. Expression of activated Notch3 in transgenic mice enhances generation of T regulatory cells and protects against experimental autoimmune diabetes. J Immunol 171:4504-4511.
2. Artavanis-Tsakonas S, Rand MD, Lake RJ. 1999. Notch signaling: Cell fate control and signal integration in development. Science 284:770-776.
3. Bellavia D, Campese AF, Alesse E, Vacca A, Felli MP, Balestri A, Stoppacciaro A, Tiveron C, Tatangelo L, Giovarelli M, Gaetano C, Ruco L, Hoffman ES, Hayday AC, Lendahl U, Frati L, Gulino A, Screpanti I. 2000. Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice. EMBO J 19:3337-3348.
4. Bellavia D, Campese AF, Checquolo S, Balestri A, Biondi A, Cazzaniga G, Lendahl U, Fehling HJ, Hayday AC, Frati L, von Boehmer H, Gulino A, Screpanti I. 2002. Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis. Proc Natl Acad Sci USA 99:3788-3793.
5. Bellavia D, Campese AF, Vacca A, Gulino A, Screpanti I. 2003. Notch3, another Notch in T cell development. Semin Immunol 15:107-112.
6. Bøyum A. 1984. Separation of lymphocytes, granulocytes, and monocytes from human blood using iodinated density gradient media. Methods Enzymol 108:88-102.
7. Felli MP, Maroder M, Mitsiadis TA, Campese AF, Bellavia D, Vacca A, Mann RS, Frati L, Lendahl U, Gulino A, Screpanti I. 1999. Expression pattern of notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: Distinct ligand-receptor interactions in intrathymic T cell development. Int Immunol 11:1017-1025.
8. Jarriault S, Brou C, Logeat F, Schroeter EH, Kopan R, Israel A. 1995. Signalling downstream of activated mammalian Notch. Nature 377:355-358.
9. Jia L, Yu G, Zhang Y, Wang MM. 2009. Lysosome-dependent degradation of Notch3. Int J Biochem Cell Biol 41:2594-2598.
10. Joutel A, Andreux F, Gaulis S, Domenga V, Cecillon M, Battail N, Piga N, Chapon F, Godfrain C, Tournier-Lasserve E. 2000. The ectodomain of the Notch3 receptor accumulates within the cerebrovasculature of CADASIL patients. J Clin Invest 105:597-605.
11. Kopan R. 2002. Notch: A membrane-bound transcription factor. J Cell Sci 115:1095-1097.
12. Larsson C, Lardelli M, White I, Lendahl U. 1994. The human NOTCH1, 2, and 3 genes are located at chromosome positions 9q34, 1p13-p11, and 19p13.2-p13.1 in regions of neoplasia-associated translocation. Genomics 24:253-258.
13. Livak KJ, Schmittgen TD. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25:402-408.
14. Meng H, Zhang X, Hankenson KD, Wang MM. 2009. Thrombospondin 2 potentiates notch3/jagged1 signaling. J Biol Chem 284:7866-7874.
15. Miele L, Osborne B. 1999. Arbiter of differentiation and death: Notch signaling meets apoptosis. J Cell Physiol 181:393-409.
16. Purow BW, Haque RM, Noel MW, Su Q, Burdick MJ, Lee J, Sundaresan T, Pastorino S, Park JK, Mikolaenko I, Maric D, Eberhart CG, Fine HA. 2005. Expression of Notch-1 and its ligands, Delta-like-1 and Jagged-1, is critical for glioma cell survival and proliferation. Cancer Res 65:2353-2363.
17. Radtke F, Wilson A, MacDonald HR. 2004. Notch signaling in T- and B-cell development. Curr Opin Immunol 16:174-179.
18. Saiki S, Sakai K, Saiki M, Kitagawa Y, Umemori T, Murata K, Matsui M, Hirose G. 2006. Varicose veins associated with CADASIL result from a novel mutation in the Notch3 gene. Neurology 67:337-339.
19. Tsukada Y, Fang J, Erdjument-Bromage H, Warren ME, Borchers CH, Tempst P, Zhang Y. 2006. Histone demethylation by a family of JmjC domain-containing proteins. Nature 439:811-816.
20. Wang T, Holt CM, Xu C, Ridley C, Jones RP, Baron M, Trump D. 2007. Notch3 activation modulates cell growth behaviour and cross-talk to Wnt/TCF signalling pathway. Cell Signal 19:2458-2467.
21. Zhang Y, Jia L, Lee SJ, Wang MM. 2007. Conserved signal peptide of Notch3 inhibits interaction with proteasome. Biochem Biophys Res Commun 355:245-251.