High prevalence of drug resistance in animal trypanosomes without a history of drug exposure

PLoS Neglected Tropical Diseases

Volumn 5, Issue 12, 2011, Pages

  Chitanga, Simbarashe ^a,b   Marcotty, Tanguy ^a,c   Namangala, Boniface ^b   van den Bossche, Peter ^a,c   van den Abbeele, Jan ^a   Delespaux, Vincent ^a  

^a INSTITUTE OF TROPICAL MEDICINE   (Belgium)

^b UNIVERSITY OF ZAMBIA   (Zambia)

^c UNIVERSITY OF PRETORIA   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

DIMINAZENE ACETURATE; DNA 18S; ANTIPROTOZOAL AGENT; DIMINAZENE; DRUG DERIVATIVE; PROTOZOAL DNA;

ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG EXPOSURE; DRUG SENSITIVITY; GENE; GENE MUTATION; GENETIC LINKAGE; MOUSE; NAGANA; NONHUMAN; P2 TYPE PURINE TRANSPORTER GENE; PARASITE ISOLATION; PARASITE PREVALENCE; PARASITE SURVIVAL; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SPECIES DIFFERENCE; TSETSE FLY; WILDLIFE; AFRICA SOUTH OF THE SAHARA; AFRICAN TRYPANOSOMIASIS; ANIMAL; DISEASE MODEL; DRUG RESISTANCE; GENETIC SELECTION; GENETICS; ISOLATION AND PURIFICATION; PARASITOLOGY; TRYPANOSOMA CONGOLENSE;

AFRICA SOUTH OF THE SAHARA; ALLELES; ANIMALS; ANTIPROTOZOAL AGENTS; DIMINAZENE; DISEASE MODELS, ANIMAL; DNA, PROTOZOAN; DRUG RESISTANCE; MICE; POLYMERASE CHAIN REACTION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; SELECTION, GENETIC; TRYPANOSOMA CONGOLENSE; TRYPANOSOMIASIS, AFRICAN;

EID: 84855261933     PISSN: 19352727     EISSN: 19352735     Source Type: Journal    
DOI: 10.1371/journal.pntd.0001454     Document Type: Article

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