-
2
-
-
0035977171
-
Is cancer mortality increasing in france?
-
DOI 10.1054/bjoc.2001.2141
-
Hill C, Jan P, Doyon F. Is cancer mortality increasing in France? Br J Cancer 2001;85:1664-6. (Pubitemid 34081509)
-
(2001)
British Journal of Cancer
, vol.85
, Issue.11
, pp. 1664-1666
-
-
Hill, C.1
Jan, P.2
Doyon, F.3
-
3
-
-
4344668629
-
Breast cancer with synchronous metastases: Trends in survival during a 14-year period
-
DOI 10.1200/JCO.2004.08.095
-
Andre F, Slimane K, Bachelot T, et al. Breast cancer with synchronous metastases: trends in survival during a 14-year period. J Clin Oncol 2004;22:3302-8. (Pubitemid 41103686)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.16
, pp. 3302-3308
-
-
Andre, F.1
Slimane, K.2
Bachelot, T.3
Dunant, A.4
Namer, M.5
Barrelier, A.6
Kabbaj, O.7
Spano, J.P.8
Marsiglia, H.9
Rouzier, R.10
Delaloge, S.11
Spielmann, M.12
-
4
-
-
79959366569
-
Medical treatments of endocrine-sensitive Her-2 negative breast cancers: A review
-
doi: 10.1684/bdc.2011.1367 (Review French)
-
Debled M, Dalenc F, Mauriac L, Brain E. Medical treatments of endocrine-sensitive Her-2 negative breast cancers: a review. Bull Cancer 2011;98:655-70. doi: 10.1684/bdc.2011.1367 (Review French).
-
(2011)
Bull Cancer
, vol.98
, pp. 655-670
-
-
Debled, M.1
Dalenc, F.2
Mauriac, L.3
Brain, E.4
-
5
-
-
19344364880
-
Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: An overview of the randomised trials
-
Early Breast Cancer Trialists' Collaborative Group.
-
Early Breast Cancer Trialists' Collaborative Group. Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials. Lancet 2005;365:1687-717.
-
(2005)
Lancet
, vol.365
, pp. 1687-1717
-
-
-
6
-
-
78650156314
-
Molecular prognostic and predictive markers of breast cancer treatment
-
Review French
-
De Cremoux P. Molecular prognostic and predictive markers of breast cancer treatment. Bull Cancer 2010;97:1297-304 (Review French).
-
(2010)
Bull Cancer
, vol.97
, pp. 1297-1304
-
-
De Cremoux, P.1
-
7
-
-
11244296162
-
Mechanisms of tamoxifen resistance
-
DOI 10.1677/erc.1.00776
-
Ring A, Dowsett M. Mechanisms of tamoxifen resistance. Endocr Relat Cancer 2004;11:643-58. (Pubitemid 40065543)
-
(2004)
Endocrine-Related Cancer
, vol.11
, Issue.4
, pp. 643-658
-
-
Ring, A.1
Dowsett, M.2
-
8
-
-
6944235337
-
Inhibition of mTOR activity restores tamoxifen response in breast cancer cells with aberrant Akt activity
-
DOI 10.1158/1078-0432.CCR-04-0035
-
de Graffenried LA, Friedrichs WE, Russell DH, et al. Inhibition of mTOR activity restores tamoxifen response in breast cancer cells with aberrant Akt activity. Clin Cancer Res 2004;10:8059-67. (Pubitemid 39587547)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.23
, pp. 8059-8067
-
-
DeGraffenried, L.A.1
Friedrichs, W.E.2
Russell, D.H.3
Donzis, E.J.4
Middleton, A.K.5
Silva, J.M.6
Roth, R.A.7
Hidalgo, M.8
-
9
-
-
22344446415
-
Dual inhibition of mTOR and estrogen receptor signaling in vitro induces cell death in models of breast cancer
-
DOI 10.1158/1078-0432.CCR-04-2402
-
Boulay A, Rudloff J, Ye J, et al. Dual inhibition of mTOR and estrogen receptor signaling in vitro induces cell death in models of breast cancer. Clin Cancer Res 2005;11:5319-28. (Pubitemid 41003721)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.14
, pp. 5319-5328
-
-
Boulay, A.1
Rudloff, J.2
Ye, J.3
Zumstein-Mecker, S.4
O'Reilly, T.5
Evans, D.B.6
Chen, S.7
Lane, H.A.8
-
11
-
-
18244391514
-
Activation of Akt/PKB in breast cancer predicts a worse outcome among endocrine treated patients
-
DOI 10.1038/sj.bjc.6600126
-
Perez-Tenorio G, Stal O. Activation of AKT/PKB in breast cancer predicts a worse outcome among endocrine treated patients. Br J Cancer 2002;86:540-5. (Pubitemid 34185089)
-
(2002)
British Journal of Cancer
, vol.86
, Issue.4
, pp. 540-545
-
-
Perez-Tenorio, G.1
Stal, O.2
Arnesson, L.G.3
Malmstrom, A.4
Nordenskjold, B.5
Nordenskjold, K.6
Ba, H.7
Kallstrom, A.Ch.8
Einarsson, E.9
Norberg, B.10
Skoog, P.11
Henning, A.12
Sundquist, M.13
Tejler, G.14
-
12
-
-
0036633164
-
Constitutive and inducible Akt activity promotes resistance to chemotherapy, trastuzumab, or tamoxifen in breast cancer cells
-
Clark AS, West K, Streicher S, Dennis PA. Constitutive and inducible Akt activity promotes resistance to chemotherapy, trastuzumab, or tamoxifen in breast cancer cells. Mol Cancer Ther 2002;1:707-17.
-
(2002)
Mol Cancer Ther
, vol.1
, pp. 707-717
-
-
Clark, A.S.1
West, K.2
Streicher, S.3
Dennis, P.A.4
-
13
-
-
0035971181
-
Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: A new model for anti-estrogen resistance
-
Campbell RA, Bhat-Nakshatri P, Patel NM, Constantinidou D, Ali S, Nakshatri H. Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance. J Biol Chem 2001;276:9817-24.
-
(2001)
J Biol Chem
, vol.276
, pp. 9817-9824
-
-
Campbell, R.A.1
Bhat-Nakshatri, P.2
Patel, N.M.3
Constantinidou, D.4
Ali, S.5
Nakshatri, H.6
-
14
-
-
34548187212
-
Akt-induced endocrine therapy resistance is reversed by inhibition of mTOR signaling
-
DOI 10.1093/annonc/mdm170
-
Beeram M, Tan QT, Tekmal RR, Russell D, Middleton A, De Graffenried LA. Akt-induced endocrine therapy resistance is reversed by inhibition of mTOR signaling. Ann Oncol 2007;18:1323-8. (Pubitemid 47305004)
-
(2007)
Annals of Oncology
, vol.18
, Issue.8
, pp. 1323-1328
-
-
Beeram, M.1
Tan, Q.-T.N.2
Tekmal, R.R.3
Russell, D.4
Middleton, A.5
DeGraffenried, L.A.6
-
16
-
-
33845947046
-
Activité clinique du CCI779 (temsirolimus), inhibiteur de mTOR
-
DOI 10.1684/bdc.2006.0152
-
Mounier N, Vignot S, Spano JP. Activité clinique du CCI779 (temsirolimus), inhibiteur de mTOR. Bull Cancer 2006;93:1139-43. (Pubitemid 46032379)
-
(2006)
Bulletin du Cancer
, vol.93
, Issue.11
, pp. 1139-1143
-
-
Mounier, N.1
Vignot, S.2
Spano, J.-P.3
-
17
-
-
23944439945
-
Phase II study of temsirolimus (CCI-779), a novel inhibitor of mTOR, in heavily pretreated patients with locally advanced or metastatic breast cancer
-
DOI 10.1200/JCO.2005.66.130
-
Chan S, Scheulen ME, Johnston S, et al. Phase II study of temsirolimus (CCI-779), a novel inhibitor of mTOR, in heavily pretreated patients with locally advanced or metastatic breast cancer. J Clin Oncol 2005;23:5314-22. (Pubitemid 46206985)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.23
, pp. 5314-5322
-
-
Chan, S.1
Scheulen, M.E.2
Johnston, S.3
Mross, K.4
Cardoso, F.5
Dittrich, C.6
Eiermann, W.7
Hess, D.8
Morant, R.9
Semiglazov, V.10
Borner, M.11
Salzberg, M.12
Ostapenko, V.13
Illiger, H.-J.14
Behringer, D.15
Bardy-Bouxin, N.16
Boni, J.17
Kong, S.18
Cincotta, M.19
Moore, L.20
more..
-
18
-
-
34848885214
-
Treatment of post menopausal women with locally advanced or metastatic breast cancer with letrozole alone or in combination with temsirolimus: A randomized, 3-arm, phase Ii study
-
Baselga J, Roché H, Fumoleau P, et al. Treatment of post menopausal women with locally advanced or metastatic breast cancer with letrozole alone or in combination with temsirolimus: a randomized, 3-arm, phase Ii study. Breast Cancer Res Treat 2005;94:S62.
-
(2005)
Breast Cancer Res Treat
, vol.94
-
-
Baselga, J.1
Roché, H.2
Fumoleau, P.3
-
19
-
-
85031199689
-
Phase 3 study of temsirolimus with letrozole in locally advanced or metastatic breast cancer
-
abstract 6091
-
Chow LWC, Sun Y, Jassem J, et al. Phase 3 study of temsirolimus with letrozole in locally advanced or metastatic breast cancer. SABCS meeting 2006 (abstract 6091).
-
SABCS Meeting 2006
-
-
Chow, L.W.C.1
Sun, Y.2
Jassem, J.3
-
20
-
-
0033610455
-
A phase I study of a 4-week course of SDZ-RAD (RAD) in quiescent cyclosporine-prednisone-treated renal transplant recipients
-
DOI 10.1097/00007890-199910270-00007
-
Kahan BD, Wong RL, Carter C, et al. A phase I study of a 4- week course of SDZ-RAD (RAD) quiescent cyclosporine-prednisone-treated renal transplant recipients. Transplantation 1999;68:1100-6. (Pubitemid 29517697)
-
(1999)
Transplantation
, vol.68
, Issue.8
, pp. 1100-1106
-
-
Kahan, B.D.1
Wong, R.L.2
Carter, C.3
Katz, S.H.4
Von Fellenberg, J.5
Van Buren, C.T.6
Appel-Dingemanse, S.7
-
22
-
-
0042804378
-
In vivo activity of RAD 001, an orally active rapamycin derivative, in experimental tumor models
-
abstract 359
-
O'Reilly T, Vaxelaire J, Muller MJ, et al. In vivo activity of RAD 001, an orally active rapamycin derivative, in experimental tumor models. Proc Am Assoc Cancer Res 2002 (abstract 359).
-
(2002)
Proc Am Assoc Cancer Res
-
-
O'Reilly, T.1
Vaxelaire, J.2
Muller, M.J.3
-
23
-
-
9144233506
-
Antitumor Efficacy of Intermittent Treatment Schedules with the Rapamycin Derivative RAD001 Correlates with Prolonged Inactivation of Ribosomal Protein S6 Kinase 1 in Peripheral Blood Mononuclear Cells
-
DOI 10.1158/0008-5472.CAN-3554-2
-
Boulay A, Zumstein-Mecker S, Stephan C, et al. Antitumor efficacy of intermittent treatment schedules with the rapamycin derivative RAD001 correlates with prolonged inactivation of ribosomal protein S6 kinase 1 in peripheral blood mononuclear cells. Cancer Res 2004;64:252-61. (Pubitemid 38114106)
-
(2004)
Cancer Research
, vol.64
, Issue.1
, pp. 252-261
-
-
Boulay, A.1
Zumstein-Mecker, S.2
Stephan, C.3
Beuvink, I.4
Zilbermann, F.5
Haller, R.6
Tobler, S.7
Heusser, C.8
O'Reilly, T.9
Stolz, B.10
Marti, A.11
Thomas, G.12
Lane, H.A.13
-
24
-
-
0345617103
-
A phase I study of the oral mTOR inhibitor RAD-001 as monotherapy to identify the optimal biologically effective dose using toxicity, pharmacokinetic (PK) and pharmacodynamic (PD) endpoints in patients with solid tumors
-
abstract 802
-
O'Donnell A, Faivre S, Judson I, et al. A phase I study of the oral mTOR inhibitor RAD-001 as monotherapy to identify the optimal biologically effective dose using toxicity, pharmacokinetic (PK) and pharmacodynamic (PD) endpoints in patients with solid tumors. Proc Am Soc Clin Oncol 2003 (abstract 802).
-
(2003)
Proc Am Soc Clin Oncol
-
-
O'Donnell, A.1
Faivre, S.2
Judson, I.3
-
25
-
-
28344456323
-
A phase I study with tumor molecular pharmacodynamic (MPD) evaluation of dose and schedule of the oral mTOR-inhibitor everolimus (RAD001) in patients (pts) with advanced solid tumors
-
abstract 3007
-
Tabernero J, Rojo F, Burris H, Casado A, Macarulla T, Jones S. A phase I study with tumor molecular pharmacodynamic (MPD) evaluation of dose and schedule of the oral mTOR-inhibitor everolimus (RAD001) in patients (pts) with advanced solid tumors. Proc Am Soc Clin Oncol 2005 (abstract 3007).
-
(2005)
Proc Am Soc Clin Oncol
-
-
Tabernero, J.1
Rojo, F.2
Burris, H.3
Casado, A.4
Macarulla, T.5
Jones, S.6
-
26
-
-
37149020235
-
The oral mTOR inhibitor RAD001 (everolimus) in combination with letrozole in patients with advanced breast cancer: Results of a phase I study with pharmacokinetics
-
DOI 10.1016/j.ejca.2007.10.003, PII S0959804907007939
-
Awada A, Cardoso F, Fontaine C, et al. The oral mTOR inhibitor RAD001 (everolimus) in combination with letrozole in patients with advanced breast cancer: results of a phase I study with pharmacokinetics. Eur J Cancer 2008;44:84-91. (Pubitemid 350256937)
-
(2008)
European Journal of Cancer
, vol.44
, Issue.1
, pp. 84-91
-
-
Awada, A.1
Cardoso, F.2
Fontaine, C.3
Dirix, L.4
De Greve, J.5
Sotiriou, C.6
Steinseifer, J.7
Wouters, C.8
Tanaka, C.9
Zoellner, U.10
Tang, P.11
Piccart, M.12
-
27
-
-
66849136781
-
Phase II randomized study of neoadjuvant everolimus plus letrozole compared with placebo plus letrozole in patients with estrogen receptor-positive breast cancer
-
Baselga J, Semiglazov V, van Dam P, et al. Phase II randomized study of neoadjuvant everolimus plus letrozole compared with placebo plus letrozole in patients with estrogen receptor-positive breast cancer. J Clin Oncol 2009;27:2630-7.
-
(2009)
J Clin Oncol
, vol.27
, pp. 2630-2637
-
-
Baselga, J.1
Semiglazov, V.2
Van Dam, P.3
-
28
-
-
85031207912
-
TAMRAD: A GINECO randomized phaseII trial of everolimus in combination with tamoxifen alone in patients with hormone-receptor positive, HER2 negative metastatic breast cancer with prior exposure to aromatase inhibitors
-
abstract S1-6
-
Bachelot T, Bourgier C, Cropet C, et al. TAMRAD: a GINECO randomized phaseII trial of everolimus in combination with tamoxifen alone in patients with hormone-receptor positive, HER2 negative metastatic breast cancer with prior exposure to aromatase inhibitors. SABCS 2010 (abstract S1-6).
-
SABCS 2010
-
-
Bachelot, T.1
Bourgier, C.2
Cropet, C.3
|