Immunohistochemical analysis of oral dysplasia: Diagnostic assessment by fascin and podoplanin expression

Acta Histochemica et Cytochemica

Volumn 44, Issue 6, 2011, Pages 239-245

  Shimamura, Yumiko ^a,b   Abe, Takahiro ^a,b   Nakahira, Mitsuhiko ^a   Yoda, Tetsuya ^b   Murata, Shin Ichi ^a   Sugasawa, Masashi ^a  

^a SAITAMA MEDICAL UNIVERSITY INTERNATIONAL MEDICAL CENTER   (Japan)

^b SAITAMA MEDICAL UNIVERSITY   (Japan)

Author keywords

CIS; Fascin; Immunohistochemistry; Oral dysplasia; Podoplanin

Indexed keywords

EID: 84855246094     PISSN: 00445991     EISSN: 13475800     Source Type: Journal    
DOI: 10.1267/ahc.11032     Document Type: Article

References (37)

1. Abbey, L. M., Kaugars, G. E., Gunsolley, J. C., Burns, J. C., Page, D. G., Svirsky, J. A., Eisenberg, E., Krutchkoff, D. J. and Cushing, M. (1995) Intraexaminer and interexaminer reliability in the diagnosis of oral epithelial dysplasia. Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod. 80; 188-191.
2. Adams, J. C. (2004) Roles of fascin in cell adhesion and motility. Curr. Opin. Cell Biol. 16; 590-596.
3. Breiteneder-Geleff, S., Soleiman, A., Kowalski, H., Horvat, R., Amann, G., Kriehuber, E., Diem, K., Weinger, W., Tschachler, E., Alitalo, K. and Kerjaschki, D. (1999) Angiosarcomas express mixed endothelial phenotypes of blood and lymphatic capillaries. Am. J. Pathol. 154; 385-394.
4. Chen, S. F., Yang, S. F., Li, J. W., Nieh, P. C., Lin, S. Y., Fu, E., Bai, C. Y., Jin, J. S., Lin, C. Y. and Nieh, S. (2007) Expression of fascin in oral and oropharyngeal squamous cell carcinomas has prognostic significance-a tissue microarray study of 129 cases. Histopathology 51; 173-183.
5. Gale, N., Pilch, B. Z. and Sidransky, D. (2005) Tumours of oral cavity and oropharynx. In "Pathology and Genetics of Head and Neck Tumours, World Health Organization (WHO) Classification of Tumours", ed. by L. Barnes, J. W. Eveson and P. Reichart, WHO Press, Geneva: IARC Press, Lyon, pp. 177-179.
6. Goncharuk, V. N., Ross, J. S. and Carlson, J. A. (2002) Actinbinding protein fascin expression in skin neoplasia. J. Cutan. Pathol. 29; 430-438.
7. Grothey, A., Hashizume, R., Sahin, A. A. and McCrea, P. D. (2000) Fascin, an actin-bundling protein associated with cell motility, is upregulated in hormone receptor negative breast cancer. Br. J. Cancer 83; 870-873.
8. Hansen, T., Katenkamp, K., Bittinger, F., Kirkpatrick, C. J. and Katenkamp, D. (2007) D2-40 labeling in lymphangiomyoma/ lymphangiomyomatoss of the soft tissue: further evidence of lymphangiogenic tumor histogenesis. Virchows Arch. 450; 449-453.
9. Hashimoto, Y., Ito, T., Inoue, H., Okumura, T., Tanaka, E., Tsunoda, S., Higashiyama, M., Watanabe, G., Imamura, M. and Shimada, Y. (2005) Prognostic significance of fascin overexpression in human esophageal squamous cell carcinoma. Clin. Cancer Res. 11; 2597-2605.
10. Hashimoto, Y., Skacel, M., Lavery, I. C., Mukherjee, A. L., Casey, G. and Adams, J. C. (2006) Prognostic significance of fascin expression in advanced colorectal cancer: an immunohistochemical study of colorectal adenoma and adenocarcinoma. BMC Cancer 6; 241.
11. Hashimoto, Y., Parsons, M. and Adams, J. C. (2007) Dual actinbunding and protein kinase C-binding acrivities of fascin regulate carcinoma cell migration downstream of Rac and contribute to metastasis. Mol. Biol. Cell. 18; 4591-4602.
12. Jawhari, A. U., Buda, A., Jenkins, M., Shehzad, K., Sarraf, C., Noda, M., Farthing, M. J., Pignatelli, M. and Adams, J. C. (2003) Fascin, an actin-bundling protein, modulates colonic epithelial cell invasiveness and differentiation in vitro. Am. J. Pathol. 162; 69-80.
13. Karabulut, A., Reibel, J., Therkildsen, M. H., Praetourius, F., Nielsen, H. W. and Dabelsteen, E. (1995) Observer variability in the histologic assessment of oral premalignant lesions. J. Pathol. Med. 24; 198-200.
14. Kawaguchi, H., El-Naggar, A. K., Papadimitrakopoulou, V., Ren, H., Fan, Y. H., Feng, L., Lee, J. J., Kim, E., Hong, W. K., Lippman, S. M. and Mao, L. (2008) Podoplanin: a novel marker for oral cancer risk in patients with oral premalignancy. J. Clin. Oncol. 26; 354-360.
15. Kimura, N. and Kimura, I. (2005) Podoplanin as a marker for mesothelioma. Pathol. Int. 55; 83-86.
16. Kreppel, M., Scheer, M., Drebber, U., Ritter, L. and Zoller, J. E. (2010) Impact of podoplanin expression in oral squamous cell carcinoma: clinical and histopathologic correlations. Virchows Arch. 456; 473-482.
17. Lee, J. J., Hong, W. K., Hittelman, W. N., Mao, L., Lotan, R., Shin, D. M., Benner, S. E., Xu, X. C., Lee, J. S., Papadimitrakopoulou, V. M., Geyer, C., Perez, C., Martion, J. W., El-Naggar, A. K. and Lippman, S. M. (2000) Predicting cancer development in oral leukoplakia: ten years of translational research. Clin. Cancer. Res. 6; 1702-1710.
18. Lee, T. K., Poon, R. T. P., Man, K., Guan, X. Y., Ma, S., Liu, X. B., Myers, J. N. and Yuen, A. P. W. (2007) Fascin over-expression is associated with aggressiveness of oral squamous cell carcinoma. Cancer Lett. 254; 308-315.
19. Maitra, A., Iacobuzio-Donahue, C., Rahman, A., Sohn, T. A., Argani, P., Meyer, R., Yeo, C. J., Cameron, J. L., Goggins, M., Kern, S. E., Ashfaq, R., Hruban, R. H. and Wilentz, R. E. (2002) Immunohistochemical validation of a novel epithelial and a novel stromal marker of pancreatic ductal adenocarcinoma identified by global expression microarrays: sea urchin fascin homolog and heat shock protein 47. Am. J. Clin. Pathol. 118; 52-59.
20. Martin-Villar, E., Megias, D., Castel, S., Yurrita, M. M., Vilaro, S. and Quintanilla, M. (2006) Podoplanin binds ERM proteins to activate RhoA and promote epithelial-mesenchymal transition. J. Cell Sci. 119; 4541-4553.
21. Mishima, K., Kato, Y., Kaneko, M. K., Nakazawa, Y., Kunita, A., Fujita, N., Tsuruo, T., Nishikawa, R., Hirose, T. and Matsutani, M. (2006) Podoplanin expression in primary central nervous system germ cell tumors: a useful histological marker for the diagnosis of germinoma. Acta Neuropathol. 111; 563-568.
22. Moustakas, A. and Heldin, C. H. (2007) Signaling networks guiding epithelial-mesenchymal transitions during embryogenesis and cancer progression. Cancer Sci. 98; 1515-1520.
23. Noda, Y., Amano, I., Hata, M., Kojima, H. and Sawa, Y. (2010) Immunohistochemical examination on the distribution of cells expressed lymphatic endothelial marker podoplanin and LYVE-1 in the mouse tongue tissue. Acta Histochem. Cytochem. 43; 61-68.
24. Pelosi, G., Pastorino, U., Pasini, F., Maissoneuve, P., Fraggeta, F., Iannucci, A., Sonzogni, A., De Manzoni, G., Terzi, A., Durante, E., Bresola, E., Pezzella, F. and Viale, G. (2003) Independent prognostic value of fascin immunoreactivity in stage I nonsmall cell lung cancer. Br. J. Cancer 88; 537-547.
25. Raica, M., Cimpean, A. M. and Ribatti, D. (2008) The role of podoplanin in tumor progression and metastasis. Anticancer Res. 28; 2997-3006.
26. Ranadiani, N., Ikeda, J., Makino, T., Tian, T., Qiu, Y., Mamat, S., Wang, Y., Doki, Y., Aozasa, K. and Mrii, E. (2010) Tumorigenic role of podoplanin in esophagel squamous-cell carcinoma. Ann. Surg. Oncol. 17; 1311-1323.
27. Schacht, V., Daras, S. S., Johnson, L. A., Jackson, D. G., Hong, Y. K. and Detmar, M. (2005) Up-regulation of the lymphatic marker podoplanin, a mucin-type transmembrane glycoprotein, in human squamous cell carcinoma and germ cell tumors. Am. J. Pathol. 166; 913-921.
28. Shi, P., Liu, W., Zhou, Z. T., He, Q. B. and Jiang, W. W. (2010) Podoplanin and ABCG2: malignant transformation risk markers for oral lichen planus. Cancer Epidemiol. Biomarkers Prev. 19; 844-849.
29. Silverman, S. Jr., Gorsky, M. and Lozada, F. (1984) Oral leukoplakia and malignant transformation. A follow-up study of 257 patients. Cancer 53; 563-568.
30. Wang, A., Liu, H. and Zhang, Y. (2007) Increased expression of fascin associated with malignant transformation of sinonasal inverted papilloma. Chin. Med. J. 120; 375-379.
31. Warnakulasuriya, S. (2009) Global epidemiology of oral and oropharyngeal cancer. Oral Oncol. 45; 309-316.
32. Wicki, A. and Christofori, G. (2007) The potential role of podoplanin in tumour invasion. Br. J. Cancer. 96; 1-5.
33. Wicki, A., Lehembre, F., Wick, N., Hantusch, B., Kerjaschki, D. and Christofori, G. (2006) Tumor invasion the absence of epithelial-mesenchymal transition: Podoplanin-mediated remodeling of the actin cytoskeleton. Cancer Cell 9; 261-272.
34. Yamaguchi, H., Inoue, T., Eguchi, T., Miyasaka, Y., Ohuchida, K., Mizumoto, K., Yamada, T., Yamaguchi, K., Tanaka, M. and Tsuneyoshi, M. (2007) Fascin overexpression in intraductal papillary mucinous neoplasms (adenomas, borderline neoplasms, and carcinomas) of the pancreas, correlated with increased histological grade. Mod. Pathol. 20; 552-561.
35. Yoder, B. J., Tso, E., Skacel, M., Pattay, J., Tarr, S., Budd, T., Tubbs, R. R., Adams, J. C. and Hicks, D. G. (2005) The expression of fascin, an actin-bunding motility protein, correlates with hormone receptor-negative breast cancer and a more aggressive clinical course. Clin. Cancer Res. 11; 186-192.
36. Yuan, P., Temam, S., El-Naggar, A., Zhou, X., Lui, D. D., Lee, J. J. and Mao, L. (2006) Overexpression of podoplanin in oral cancer and its association with poor clinical outcome. Cancer 107; 563-569.
37. Zhang, H., Xu, L., Xiao, D., Xie, J., Zeng, H., Cai, W., Niu, Y., Yang, Z., Shen, Z. and Li, E. (2006) Fascin is a potential biomarker for early-stage oesophageal squamous cell carcinoma. J. Clin. Pathol. 59; 958-964.