메뉴 건너뛰기




Volumn 26, Issue 6, 2011, Pages 637-645

Single nucleotide polymorphisms in the human Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) Gene

Author keywords

Aryl hydrocarbon receptor nuclear translocator; Dioxin; Ethnicity; Single nucleotide polymorphism

Indexed keywords

ALANINE; HYPOXIA INDUCIBLE FACTOR 1BETA; METHIONINE; THREONINE; VALINE;

EID: 84855241733     PISSN: 13474367     EISSN: 18800920     Source Type: Journal    
DOI: 10.2133/dmpk.DMPK-11-SC-031     Document Type: Article
Times cited : (9)

References (39)
  • 2
    • 30044452058 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor regulates distinct dioxin-dependent and dioxin-independent gene batteries
    • Tijet, N., Boutros, P. C., Moffat, I. D., Okey, A. B., Tuomisto, J. and Pohjanvirta, R.: Aryl hydrocarbon receptor regulates distinct dioxin-dependent and dioxin-independent gene batteries. Mol. Pharmacol., 69: 140-153 2006.
    • (2006) Mol. Pharmacol , vol.69 , pp. 140-153
    • Tijet, N.1    Boutros, P.C.2    Moffat, I.D.3    Okey, A.B.4    Tuomisto, J.5    Pohjanvirta, R.6
  • 3
    • 71049164157 scopus 로고    scopus 로고
    • Comparative analysis of AhR-mediated TCDD-elicited gene expression in human liver adult stem cells
    • Kim, S., Dere, E., Burgoon, L. D., Chang, C. C. and Zacharewski, T. R.: Comparative analysis of AhR-mediated TCDD-elicited gene expression in human liver adult stem cells. Toxicol. Sci., 112: 229-244 2009.
    • (2009) Toxicol. Sci , vol.112 , pp. 229-244
    • Kim, S.1    Dere, E.2    Burgoon, L.D.3    Chang, C.C.4    Zacharewski, T.R.5
  • 4
    • 77951210260 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor AHR-regulated transcriptomic changes in rats sensitive or resistant to major dioxin toxicities
    • Moffat, I. D., Boutros, P. C., Chen, H., Okey, A. B. and Pohjanvirta, R.: Aryl hydrocarbon receptor AHR-regulated transcriptomic changes in rats sensitive or resistant to major dioxin toxicities. BMC Genomics, 11: 263-278 2010.
    • (2010) BMC Genomics , vol.11 , pp. 263-278
    • Moffat, I.D.1    Boutros, P.C.2    Chen, H.3    Okey, A.B.4    Pohjanvirta, R.5
  • 5
    • 0030888748 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor- mediated signal transduction
    • Rowlands, J. C. and Gustafsson, J. A.: Aryl hydrocarbon receptor- mediated signal transduction. Crit. Rev. Toxicol., 27: 109-134 1997.
    • (1997) Crit. Rev. Toxicol , vol.27 , pp. 109-134
    • Rowlands, J.C.1    Gustafsson, J.A.2
  • 6
    • 9344230351 scopus 로고    scopus 로고
    • Gestational exposure of Ahr and Arnt hypomorphs to dioxin rescues vascular development
    • Walisser, J. A., Bunger, M. K., Glover, E. and Bradfield, C. A.: Gestational exposure of Ahr and Arnt hypomorphs to dioxin rescues vascular development. Proc. Natl. Acad. Sci. USA, 101: 16677-16682 2004.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 16677-16682
    • Walisser, J.A.1    Bunger, M.K.2    Glover, E.3    Bradfield, C.A.4
  • 7
    • 0031710576 scopus 로고    scopus 로고
    • Mechanisms of ligand-induced aryl hydrocarbon receptor-mediated biochemical and toxic responses
    • Wilson, C. L. and Safe, S.: Mechanisms of ligand-induced aryl hydrocarbon receptor-mediated biochemical and toxic responses. Toxicol. Pathol., 26: 657-671 1998.
    • (1998) Toxicol. Pathol , vol.26 , pp. 657-671
    • Wilson, C.L.1    Safe, S.2
  • 8
    • 0037337763 scopus 로고    scopus 로고
    • Oxygen-dependent regulation of hypoxia-inducible factors by prolyl and asparaginyl hydroxylation
    • Lando, D., Gorman, J. J., Whitelaw, M. L. and Peet, D. J.: Oxygen-dependent regulation of hypoxia-inducible factors by prolyl and asparaginyl hydroxylation. Eur. J. Biochem., 270: 781-790 2003.
    • (2003) Eur. J. Biochem , vol.270 , pp. 781-790
    • Lando, D.1    Gorman, J.J.2    Whitelaw, M.L.3    Peet, D.J.4
  • 9
    • 17544384815 scopus 로고    scopus 로고
    • ARNT-deficient mice and placental differentiation
    • Kozak, K. R., Abbott, B. and Hankinson, O.: ARNT-deficient mice and placental differentiation. Dev. Biol., 191: 297-305 1997.
    • (1997) Dev. Biol , vol.191 , pp. 297-305
    • Kozak, K.R.1    Abbott, B.2    Hankinson, O.3
  • 10
    • 0030943461 scopus 로고    scopus 로고
    • Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT
    • Maltepe, E., Schmidt, J. V., Baunoch, D., Bradfield, C. A. and Simon, M. C.: Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT. Nature, 386: 403-407 1997.
    • (1997) Nature , vol.386 , pp. 403-407
    • Maltepe, E.1    Schmidt, J.V.2    Baunoch, D.3    Bradfield, C.A.4    Simon, M.C.5
  • 13
    • 31344461643 scopus 로고    scopus 로고
    • The association of endometriosis risk and genetic polymorphisms involving dioxin detoxification enzymes: A system- atic review
    • Guo, S. W.: The association of endometriosis risk and genetic polymorphisms involving dioxin detoxification enzymes: a system- atic review. Eur. J. Obstet. Gynecol. Reprod. Biol., 124: 134-143 2006.
    • (2006) Eur. J. Obstet. Gynecol. Reprod. Biol , vol.124 , pp. 134-143
    • Guo, S.W.1
  • 14
    • 0034987564 scopus 로고    scopus 로고
    • Human arylhydrocarbon receptor repressor {currency sign}AHRR gene: Genomic structure and analysis of polymorphism in endometriosis
    • Watanabe, T., Imoto, I., Kosugi, Y., Fukuda, Y., Mimura, J., Fujii, Y., Isaka, K., Takayama, M., Sato, A. and Inazawa, J.: Human arylhydrocarbon receptor repressor {currency sign}AHRR gene: genomic structure and analysis of polymorphism in endometriosis. J. Hum. Genet., 46: 342-346 2001.
    • (2001) J. Hum. Genet , vol.46 , pp. 342-346
    • Watanabe, T.1    Imoto, I.2    Kosugi, Y.3    Fukuda, Y.4    Mimura, J.5    Fujii, Y.6    Isaka, K.7    Takayama, M.8    Sato, A.9    Inazawa, J.10
  • 15
  • 16
    • 1342309265 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor polymorphisms and dioxin resistance in Atlantic killifish {currency sign}Fundulus heteroclitus
    • Hahn, M. E., Karchner, S. I., Franks, D. G. and Merson, R. R.: Aryl hydrocarbon receptor polymorphisms and dioxin resistance in Atlantic killifish {currency sign}Fundulus heteroclitus. Pharmacogenetics, 14: 131-143 2004.
    • (2004) Pharmacogenetics , vol.14 , pp. 131-143
    • Hahn, M.E.1    Karchner, S.I.2    Franks, D.G.3    Merson, R.R.4
  • 17
    • 0030977819 scopus 로고    scopus 로고
    • Human Ah receptor {currency sign}AHR gene: Localization to 7p15 and suggestive correlation of polymorphism with CYP1A1 inducibility
    • Micka, J., Milatovich, A., Menon, A., Grabowski, G. A., Puga, A. and Nebert, D. W.: Human Ah receptor {currency sign}AHR gene: localization to 7p15 and suggestive correlation of polymorphism with CYP1A1 inducibility. Pharmacogenetics, 7: 95-101 1997.
    • (1997) Pharmacogenetics , vol.7 , pp. 95-101
    • Micka, J.1    Milatovich, A.2    Menon, A.3    Grabowski, G.A.4    Puga, A.5    Nebert, D.W.6
  • 18
    • 0027944549 scopus 로고
    • Analysis of the four alleles of the murine aryl hydrocarbon receptor
    • Poland, A., Palen, D. and Glover, E.: Analysis of the four alleles of the murine aryl hydrocarbon receptor. Mol. Pharmacol., 46: 915-921 1994.
    • (1994) Mol. Pharmacol , vol.46 , pp. 915-921
    • Poland, A.1    Palen, D.2    Glover, E.3
  • 19
    • 77957879217 scopus 로고    scopus 로고
    • Functional analysis of six human aryl hydrocarbon receptor variants in human breast cancer and mouse hepatoma cell lines
    • Celius, T. and Matthews, J.: Functional analysis of six human aryl hydrocarbon receptor variants in human breast cancer and mouse hepatoma cell lines. Toxicology, 277: 59-65 2010.
    • (2010) Toxicology , vol.277 , pp. 59-65
    • Celius, T.1    Matthews, J.2
  • 20
    • 77951432209 scopus 로고    scopus 로고
    • The human AHR: Identification of single nucleotide polymorphisms from six ethnic populations
    • Rowlands, J. C., Staskal, D. F., Gollapudi, B. and Budinsky, R.: The human AHR: identification of single nucleotide polymorphisms from six ethnic populations. Pharmacogenet. Genomics, 20: 283-290 2010.
    • (2010) Pharmacogenet. Genomics , vol.20 , pp. 283-290
    • Rowlands, J.C.1    Staskal, D.F.2    Gollapudi, B.3    Budinsky, R.4
  • 21
    • 80052580445 scopus 로고    scopus 로고
    • An evaluation of single nucleotide polymorphisms in the human aryl hydrocarbon receptor-interacting protein AIP gene
    • Rowlands, J. C., Urban, J. D., Staskal Wikoff, D. and Budinsky, R. A.: An evaluation of single nucleotide polymorphisms in the human aryl hydrocarbon receptor-interacting protein AIP gene. Drug Metab. Pharmacokinet., 26: 431-439 2011.
    • (2011) Drug Metab. Pharmacokinet , vol.26 , pp. 431-439
    • Rowlands, J.C.1    Urban, J.D.2    Staskal, W.D.3    Budinsky, R.A.4
  • 22
    • 0037453265 scopus 로고    scopus 로고
    • Identification of novel splice variants of ARNT and ARNT2 in the rat
    • Korkalainen, M., Tuomisto, J. and Pohjanvirta, R.: Identification of novel splice variants of ARNT and ARNT2 in the rat. Biochem. Biophys. Res. Commun., 303: 1095-1100 2003.
    • (2003) Biochem. Biophys. Res. Commun , vol.303 , pp. 1095-1100
    • Korkalainen, M.1    Tuomisto, J.2    Pohjanvirta, R.3
  • 23
    • 77950044558 scopus 로고    scopus 로고
    • Lost in the space of bioinformatic tools: A constantly updated survival guide for genetic epidemiology. The GenEpi Toolbox
    • Coassin, S., Brandstatter, A. and Kronenberg, F.: Lost in the space of bioinformatic tools: a constantly updated survival guide for genetic epidemiology. The GenEpi Toolbox. Atherosclerosis, 209: 321-335 2010.
    • (2010) Atherosclerosis , vol.209 , pp. 321-335
    • Coassin, S.1    Brandstatter, A.2    Kronenberg, F.3
  • 27
    • 62449277773 scopus 로고    scopus 로고
    • ARNT PAS-B has a fragile native state structure with an alternative beta-sheet register nearby in sequence space
    • Evans, M. R., Card, P. B. and Gardner, K. H.: ARNT PAS-B has a fragile native state structure with an alternative beta-sheet register nearby in sequence space. Proc. Natl. Acad. Sci. USA, 106: 2617-2622 2009.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 2617-2622
    • Evans, M.R.1    Card, P.B.2    Gardner, K.H.3
  • 28
    • 33750353461 scopus 로고    scopus 로고
    • Predicting the effects of amino acid substitutions on protein function
    • Ng, P. C. and Henikoff, S.: Predicting the effects of amino acid substitutions on protein function. Annu. Rev. Genomics Hum. Genet., 7: 61-80 2006.
    • (2006) Annu. Rev. Genomics Hum. Genet , vol.7 , pp. 61-80
    • Ng, P.C.1    Henikoff, S.2
  • 29
    • 0026764306 scopus 로고
    • Similarity of spontaneous germinal and in vitro somatic cell mutation rates in humans: Implications for carcinogenesis and for the role of exogenous factors in úspontaneousû germinal mutagenesis
    • Kuick, R. D., Neel, J. V., Strahler, J. R., Chu, E. H., Bargal, R., Fox, D. A. and Hanash, S. M.: Similarity of spontaneous germinal and in vitro somatic cell mutation rates in humans: implications for carcinogenesis and for the role of exogenous factors in úspontaneousû germinal mutagenesis. title typejournalProc. Natl. Acad. Sci/title. misctextUSA/misctext, vol89/vol: page typefirst7036/pagex-/xpage typelast7040/page 1992.
    • (1992) Proc. Natl. Acad. Sci , vol.89 , pp. 7036-7040
    • Kuick, R.D.1    Neel, J.V.2    Strahler, J.R.3    Chu, E.H.4    Bargal, R.5    Fox, D.A.6    Hanash, S.M.7
  • 31
    • 0032990441 scopus 로고    scopus 로고
    • PAS domains: Internal sensors of oxygen, redox potential, and light. Microbiol
    • Taylor, B. L. and Zhulin, I. B.: PAS domains: internal sensors of oxygen, redox potential, and light. Microbiol. Mol. Biol. Rev., 63: 479-506 1999.
    • (1999) Mol. Biol. Rev , vol.63 , pp. 479-506
    • Taylor, B.L.1    Zhulin, I.B.2
  • 32
    • 1242339670 scopus 로고    scopus 로고
    • Contribution of the Per/Arnt/Sim {currency sign}PAS domains to DNA binding by the basic helix-loop-helix PAS transcriptional regulators
    • Chapman-Smith, A., Lutwyche, J. K. and Whitelaw, M. L.: Contribution of the Per/Arnt/Sim {currency sign}PAS domains to DNA binding by the basic helix-loop-helix PAS transcriptional regulators. J. Biol. Chem., 279: 5353-5362 2004.
    • (2004) J. Biol. Chem , vol.279 , pp. 5353-5362
    • Chapman-Smith, A.1    Lutwyche, J.K.2    Whitelaw, M.L.3
  • 33
    • 2242423606 scopus 로고    scopus 로고
    • A novel mutation T65P in the PAS domain of the human potassium channel HERG results in the long QT syndrome by trafficking deficiency
    • Paulussen, A., Raes, A., Matthijs, G., Snyders, D. J., Cohen, N. and Aerssens, J.: A novel mutation T65P in the PAS domain of the human potassium channel HERG results in the long QT syndrome by trafficking deficiency. J. Biol. Chem., 277: 48610-48616 2002.
    • (2002) J. Biol. Chem , vol.277 , pp. 48610-48616
    • Paulussen, A.1    Raes, A.2    Matthijs, G.3    Snyders, D.J.4    Cohen, N.5    Aerssens, J.6
  • 34
    • 0030968826 scopus 로고    scopus 로고
    • A point mutation responsible for defective function of the aryl-hydrocarbon-receptor nuclear translocator in mutant Hepa-1c1c7 cells
    • Numayama-Tsuruta, K., Kobayashi, A., Sogawa, K. and Fujii-Kuriyama, Y.: A point mutation responsible for defective function of the aryl-hydrocarbon-receptor nuclear translocator in mutant Hepa-1c1c7 cells. Eur. J. Biochem., 246: 486-495 1997.
    • (1997) Eur. J. Biochem , vol.246 , pp. 486-495
    • Numayama-Tsuruta, K.1    Kobayashi, A.2    Sogawa, K.3    Fujii-Kuriyama, Y.4
  • 35
    • 77956629568 scopus 로고    scopus 로고
    • Computational and structural analysis of deleterious functional SNPs in ARNT oncogene
    • George Priya Doss, C. and Sethumadhavan, R.: Computational and structural analysis of deleterious functional SNPs in ARNT oncogene. Interdiscip. Sci., 1: 220-228 2009.
    • (2009) Interdiscip. Sci , vol.1 , pp. 220-228
    • George, P.D.C.1    Sethumadhavan, R.2
  • 36
    • 0036274035 scopus 로고    scopus 로고
    • Variability of the human aryl hydrocarbon receptor nuclear translocator ARNT gene
    • Scheel, J., Hussong, R., Schrenk, D. and Schmitz, H. J.: Variability of the human aryl hydrocarbon receptor nuclear translocator ARNT gene. J. Hum. Genet., 47: 217-224 2002.
    • (2002) J. Hum. Genet , vol.47 , pp. 217-224
    • Scheel, J.1    Hussong, R.2    Schrenk, D.3    Schmitz, H.J.4
  • 37
    • 0034103544 scopus 로고    scopus 로고
    • Human aryl hydrocarbon receptor nuclear translocator gene ARNT D/N511 polymorphism
    • Cao, H. and Hegele, R. A.: Human aryl hydrocarbon receptor nuclear translocator gene ARNT D/N511 polymorphism. J. Hum. Genet., 45: 92-93 2000.
    • (2000) J. Hum. Genet , vol.45 , pp. 92-93
    • Cao, H.1    Hegele, R.A.2
  • 38
    • 0033658607 scopus 로고    scopus 로고
    • An uncommon phenotype of poor inducibility of CYP1A1 in human lung is not ascribable to polymorphisms in the AHR, ARNT, or CYP1A1 genes
    • Anttila, S., Lei, X. D., Elovaara, E., Karjalainen, A., Sun, W., Vainio, H. and Hankinson, O.: An uncommon phenotype of poor inducibility of CYP1A1 in human lung is not ascribable to polymorphisms in the AHR, ARNT, or CYP1A1 genes. Pharmacogenetics, 10: 741-751 2000.
    • (2000) Pharmacogenetics , vol.10 , pp. 741-751
    • Anttila, S.1    Lei, X.D.2    Elovaara, E.3    Karjalainen, A.4    Sun, W.5    Vainio, H.6    Hankinson, O.7
  • 39
    • 42449139081 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor nuclear translocator {currency sign}ARNT gene as a positional and functional candidate for type 2 diabetes and prediabetic intermediate traits: Mutation detection, case-control studies, and gene expression analysis
    • Das, S. K., Sharma, N. K., Chu, W. S., Wang, H. and Elbein, S. C.: Aryl hydrocarbon receptor nuclear translocator {currency sign}ARNT gene as a positional and functional candidate for type 2 diabetes and prediabetic intermediate traits: Mutation detection, case-control studies, and gene expression analysis. BMC Med. Genet., 9: 16-27 2008.
    • (2008) BMC Med. Genet , vol.9 , pp. 16-27
    • Das, S.K.1    Sharma, N.K.2    Chu, W.S.3    Wang, H.4    Elbein, S.C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.