Antimetastatic activity isolated from Colocasia esculenta (taro)

Anti-Cancer Drugs

Volumn 23, Issue 2, 2012, Pages 200-211

  Kundu, Namita ^a   Campbell, Patricia ^a   Hampton, Brian ^a   Lin, Chen Yong ^a   Ma, Xinrong ^a   Ambulos, Nicholas ^a   Zhao, X Frank ^a   Goloubeva, Olga ^a   Holt, Dawn ^a   Fulton, Amy M ^a,b  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b Baltimore Veterans Administration   (United States)

Author keywords

antimetastatic activity; breast cancer; cancer therapy; taro; tumor

Indexed keywords

ANTINEOPLASTIC AGENT; CARBOHYDRATE BINDING PROTEIN; COLOCASIA ESCULENTA EXTRACT; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; LECTIN; MESSENGER RNA; PLANT EXTRACT; PROGESTERONE RECEPTOR; PROSTAGLANDIN E2; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST AUGMENTATION; BREAST CANCER; BREAST CELL; CANCER CELL CULTURE; CELL MIGRATION; CELL PROLIFERATION; COLOCASIA; COLOCASIA ESCULENTA; CONTROLLED STUDY; DISEASE MODEL; DOWN REGULATION; FEMALE; METASTASIS; METASTASIS INHIBITION; MORPHOLOGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN EXPRESSION; PROTEIN SYNTHESIS;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CHROMATOGRAPHY, GEL; CHROMATOGRAPHY, REVERSE-PHASE; COLOCASIA; DINOPROSTONE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; LUNG NEOPLASMS; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; MICE, INBRED STRAINS; MOLECULAR WEIGHT; NEOPLASM TRANSPLANTATION; PLANT EXTRACTS; PLANT ROOTS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84855227492     PISSN: 09594973     EISSN: 14735741     Source Type: Journal    
DOI: 10.1097/CAD.0b013e32834b85e8     Document Type: Article

References (26)

1. Fahey JW, Zhang Y, Talalay P. Broccoli sprouts: An exceptionally rich source of inducers of enzymes that protect against chemical carcinogens. Proc Natl Acad Sci USA 1997; 94:10367-10372. (Pubitemid 27407048)
2. Kelloff GJ, Crowell JA, Steel VE, Lubet RA, Malone WA, Boone CW, et al. Progress in cancer chemoprevention: Development of diet-derived chemopreventive agents. J Nutr 2000; 130:467S-471S. (Pubitemid 30073775)
3. Liu RH. Health benefits of fruit and vegetables and from additive and synergistic combinations of phytochemicals. Am J Clin Nutr 2003; 78:517s-520s. (Pubitemid 40012543)
4. Surh YJ. Cancer chemoprevention with dietary phytochemicals. Nat Rev Cancer 2003; 3:768-780.
5. Milner JA. Molecular targets for bioactive food components. J Nutr 2004; 134:2492s-2498s. (Pubitemid 39201626)
6. Stan SD, Kar S, Stoner GD, Singh SV. Bioactive food components and cancer risk reduction. J Cell Biochem 2008; 104:339-356.
7. Stoner GD, Chen T, Kresty LA, Aziz RM, Reinemann T. Protection against esophageal cancer in rodents with lyophilized berries: Potential mechanism. Nutr Cancer 2006; 54:33-46. (Pubitemid 44141334)
8. Taketo MM. Cyclooxygenase-2 inhibitors in tumorigenasis (part I). J Natl Cancer Inst 1998; 90:1529-1536.
9. Ristimaki A, Sivula A, Lundin M, Salminen T, Haglund C, Joensuu H, et al. Prognostic significance of elevated cyclooxygenase-2 expression in breast cancer. Cancer Res 2002; 62:632-635. (Pubitemid 34126931)
10. Kundu N, Yang Q, Dorsey R, Fulton AM. Increased cyclooxygenase-2 (COX-2) expression and activity in a murine model of metastatic breast cancer. Int J Cancer 2001; 93:681-686. (Pubitemid 32695116)
11. Kundu N, Smyth MJ, Samsel L, Fulton AM. Cyclooxygenase inhibitors block cell growth, increase ceramide and inhibit cell cycle. Breast Cancer Res Treat 2002; 76:57-64. (Pubitemid 35178628)
12. Kundu N, Fulton AM. Selective cyclooxygenase (COX)-1 or COX-2 inhibitors control metastatic disease in a murine model of breast cancer. Cancer Res 2002; 62:2343-2346. (Pubitemid 34411715)
13. Brown AC, Reitzenstein JE, Liu J, Jadus MR. The anti cancer effects of poi (Colocasia esculenta) on colonic adenocarcinoma cells in vitro. Phytother Res 2005; 19:767-771. (Pubitemid 41571425)
14. Altschul SF, Madden TL, Schäffer AA, Zhang J, Zhang Z, Miller W, et al. Gapped BLAST and PSI-BLAST: A new generation of protein database search programs. Nucleic Acids Res 1997; 25:3389-3402. (Pubitemid 27359211)
15. Miller FR, Miller BE, Heppner GH. Characterization of metastatic heterogeneity among subpopulations of a single mouse mammary tumor: Heterogeneity in phenotypic stability. Inv Metas 1983; 3:22-31. (Pubitemid 13083351)
16. Lu Y, Zhou H, ChenW, Zhang Y, Hamburger AW. The ErbB3 binding protein EBP1 regulates ErbB2 protein levels and tamoxifen sensitivity in breast cancer cells. Breast Cancer Res Treat 2011; 126:27-36.
17. Price JE, Polyzos A, Zhang RD, Daniels LM. Tumorigenicity and metastasis of human breast carcinoma cell lines in nude mice. Cancer Res 1990; 50:717-721. (Pubitemid 20054204)
18. Balzer EM, Whipple RA, Cho EH, Matrone MA, Martin SS. Antimitotic chemotherapeutics promote adhesive responses in detached and circulating tumor cells. Breast Cancer Res Treat 2010; 121:65-78.
19. Lee DI, Sumbilla C, Lee M, Natesavelalar C, Klein MG, Ross DD, et al. Mechanisms of resistance and adaptation to thapsigargin in androgenindependent prostate cancer PC3 and DU145 cells. Arch Biochem Biophys 2007; 464:19-27. (Pubitemid 47088360)
20. Tang Y, Hamburger AW, Wang L, Khan MA, Hussain A. Androgen deprivation and stem cell markers in prostate cancers. Clin Exp Pathol 2010; 3:128-138.
21. Kundu N, Zhang S, Fulton AM. Sublethal oxidative stress inhibits tumor cell adhesion and enhances experimental metastasis of murine mammary carcinoma. Clin Exp Metastasis 1995; 13:16-22.
22. Hirai M, Nakamura K, Imai T, Sato T. cDNAs encoding for storage proteins in the tubers of taro (Colocasia esculenta Schott). Jpn J Genet 1993; 68:229-236. (Pubitemid 23294594)
23. Bezerra IC, Csatro LAB, Neshich G, de Almeida ERP, Grossi de Sa' MF, Mello LV, et al. A corm-specific gene encodes tarin, a major globulin of taro (Colocasia esculenta L. Schott). Plant Mol Biol 1995; 28:137-144.
24. Huang AS, Titchenal CA, Meilleur BA. Nutrient composition of taro corms and breadfruit. J Food Comp Anal 2001; 13:859-864.
25. Brown AC, Valiere A. The medicinal uses of poi. Nutr Clin Care 2004; 7: 69-74.
26. Ferguson LR, Roberton AM, Mckenzie RJ,Watson ME, Harris PJ. Adsorption of a hydrophobic mutagen to dietary fiber from taro (Colocasia esculenta), an important food plant of the South Pacific. Nutr Cancer 1992; 17:85-95.