Optimization of matrix metalloproteinase fluorogenic probes for osteoarthritis imaging

Amino Acids

Volumn 41, Issue 5, 2011, Pages 1113-1122

  Ryu, Ju Hee ^a,c   Lee, Aeju ^a   Na, Jin Hee ^a   Lee, Seulki ^a   Ahn, Hyung Jun ^a   Park, Jong Woong ^b   Ahn, Cheol Hee ^c   Kim, Byung Soo ^c   Kwon, Ick Chan ^a   Choi, Kuiwon ^a   Youn, Inchan ^a   Kim, Kwangmeyung ^a  

^a Korea Institute of Science and Technology   (South Korea)

^b Korea University College of Medicine   (South Korea)

^c Seoul National University   (South Korea)

Author keywords

Fluorogenic probe; Matrix metalloproteinase (MMP); Optical imaging; Osteoarthritis; Peptide

Indexed keywords

COLLAGENASE 3; CYANINE DYE 5; FLUORESCENT DYE; METALLOPROTEINASE INHIBITOR;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME SPECIFICITY; FLUORESCENCE ANALYSIS; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR IMAGING; MOLECULAR PROBE; NONHUMAN; OSTEOARTHRITIS; PRIORITY JOURNAL; PROCESS OPTIMIZATION; RAT; SIGNAL DETECTION;

ANIMALS; CARBOCYANINES; DISEASE MODELS, ANIMAL; FLUORESCENT DYES; HUMANS; KINETICS; MATRIX METALLOPROTEINASE 13; MOLECULAR IMAGING; MOLECULAR PROBES; OSTEOARTHRITIS; PEPTIDES; RATS; RATS, SPRAGUE-DAWLEY; SENSITIVITY AND SPECIFICITY; SPECTROSCOPY, NEAR-INFRARED;

RATTUS;

EID: 84855223512     PISSN: 09394451     EISSN: 14382199     Source Type: Journal    
DOI: 10.1007/s00726-010-0769-y     Document Type: Article

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