Investigation on the stability of the Dde protecting group used in peptide synthesis: Migration to an unprotected lysine

Journal of Peptide Research

Volumn 51, Issue 2, 1998, Pages 127-133

  Augustyns, Koen ^a,b   Kraas, Wolfgang ^a   Jung, Günther ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

1 (4,4 dimethyl 2,6 dioxocyclohexylidene)ethyl (Dde); Amine protection; DBU; Fmoc solid phase peptide synthesis; Protecting group; Side reactions in peptide synthesis

Indexed keywords

1,1 DICHLORO 2,2 BIS(4 CHLOROPHENYL)ETHYLENE; 9 FLUORENYLMETHYL CHLOROFORMATE; LYSINE; N,N DIMETHYLFORMAMIDE; PIPERIDINE; SYNTHETIC PEPTIDE;

ARTICLE; CHEMICAL REACTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MOLECULAR INTERACTION; MOLECULAR STABILITY; PEPTIDE SYNTHESIS; PRIORITY JOURNAL;

EID: 0031916180     PISSN: 1397002X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-3011.1998.tb00630.x     Document Type: Article

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