-
1
-
-
4544229980
-
Design, synthesis and preclinical evaluation of radiolabeled peptides for diagnosis and therapy
-
DOI 10.2174/1381612043383511
-
Aloj L, Morelli G (2004) Design, synthesis and preclinical evaluation of radiolabeled peptides for diagnosis and therapy. Curr Pharm Des 10:3009-3031 (Pubitemid 39214008)
-
(2004)
Current Pharmaceutical Design
, vol.10
, Issue.24
, pp. 3009-3031
-
-
Aloj, L.1
Morelli, G.2
-
2
-
-
6044261336
-
Criteria for the design and biological characterization of radiolabeled peptide-based pharmaceuticals
-
DOI 10.2165/00063030-200418050-00001
-
Benedetti E, Morelli G, Accardo A, Mansi R, Tesauro D, Aloj L (2004) Criteria for the design and biological characterization of radiolabeled peptide-based pharmaceuticals. BioDrugs 18:279-295 (Pubitemid 39381945)
-
(2004)
BioDrugs
, vol.18
, Issue.5
, pp. 279-295
-
-
Benedetti, E.1
Morelli, G.2
Accardo, A.3
Mansi, R.4
Tesauro, D.5
Aloj, L.6
-
3
-
-
11144317860
-
Hitting multiple targets with multimeric ligands
-
DOI 10.1517/14728222.8.6.565
-
Handl HL, Vagner J, Han H, Mash E, Hruby VJ, Gillies RJ (2004) Hitting multiple targets with multimeric ligands. Expert Opin Ther Targets 8:565-586 (Pubitemid 40028367)
-
(2004)
Expert Opinion on Therapeutic Targets
, vol.8
, Issue.6
, pp. 565-586
-
-
Handl, H.L.1
Vagner, J.2
Han, H.3
Mash, E.4
Hruby, V.J.5
Gilles, R.J.6
-
4
-
-
57349087103
-
Solid-phase synthesis of heterobivalent ligands targeted to melanocortin and cholecystokinin receptors
-
Josan JS, Vagner J, Handl HL, Sankaranarayanan R, Gillies RJ, Hruby VJ (2008) Solid-phase synthesis of heterobivalent ligands targeted to melanocortin and cholecystokinin receptors. Int J Pept Res Ther 14:293-300
-
(2008)
Int J Pept Res Ther
, vol.14
, pp. 293-300
-
-
Josan, J.S.1
Vagner, J.2
Handl, H.L.3
Sankaranarayanan, R.4
Gillies, R.J.5
Hruby, V.J.6
-
6
-
-
34447336118
-
3 integrin expression
-
DOI 10.2967/jnumed.107.039859
-
Li ZB, Cai W, Cao Q et al (2007) (64)Cu-labeled tetrameric and octameric RGD peptides for small-animal PET of tumor alpha(v)beta(3) integrin expression. J Nucl Med 48:1162-1171 (Pubitemid 47052657)
-
(2007)
Journal of Nuclear Medicine
, vol.48
, Issue.7
, pp. 1162-1171
-
-
Li, Z.-B.1
Cai, W.2
Cao, Q.3
Chen, K.4
Wu, Z.5
He, L.6
Chen, X.7
-
7
-
-
43749105336
-
(68)Ga-labeled multimeric RGD peptides for microPET imaging of integrin alpha (v)beta (3) expression
-
Li ZB, Chen K, Chen X (2008a) (68)Ga-labeled multimeric RGD peptides for microPET imaging of integrin alpha(v)beta (3) expression. Eur J Nucl Med Mol Imaging 35:1100-1108
-
(2008)
Eur J Nucl Med Mol Imaging
, vol.35
, pp. 1100-1108
-
-
Li, Z.B.1
Chen, K.2
Chen, X.3
-
9
-
-
33750420717
-
3 targeted radiotracers for tumor imaging
-
DOI 10.1021/mp060049x
-
Liu S (2006) Radiolabeled multimeric cyclic RGD peptides as integrin alphavbeta3 targeted radiotracers for tumor imaging. Mol Pharm 3:472-487 (Pubitemid 44639125)
-
(2006)
Molecular Pharmaceutics
, vol.3
, Issue.5
, pp. 472-487
-
-
Liu, S.1
-
10
-
-
0034742826
-
99mTc-labeling of a hydrazinonicotinamide-conjugated vitronectin receptor antagonist useful for imaging tumors
-
DOI 10.1021/bc010012p
-
Liu S, Edwards DS, Ziegler MC, Harris AR, Hemingway SJ, Barrett JA (2001) 99mTc-labeling of a hydrazinonicotinamide-conjugated vitronectin receptor antagonist useful for imaging tumors. Bioconjug Chem 12:624-629 (Pubitemid 32696237)
-
(2001)
Bioconjugate Chemistry
, vol.12
, Issue.4
, pp. 624-629
-
-
Liu, S.1
Edwards, D.S.2
Ziegler, M.C.3
Harris, A.R.4
Hemingway, S.J.5
Barrett, J.A.6
-
11
-
-
70349263634
-
Noninvasive imaging of tumor integrin expression using (18)F-labeled RGD dimer peptide with PEG (4) linkers
-
Liu Z, Liu S, Wang F, Chen X (2009a) Noninvasive imaging of tumor integrin expression using (18)F-labeled RGD dimer peptide with PEG (4) linkers. Eur J Nucl Med Mol Imaging 36:1296-1307
-
(2009)
Eur J Nucl Med Mol Imaging
, vol.36
, pp. 1296-1307
-
-
Liu, Z.1
Liu, S.2
Wang, F.3
Chen, X.4
-
12
-
-
67349145987
-
(68)Ga-labeled cyclic RGD dimers with Gly3 and PEG4 linkers: Promising agents for tumor integrin alphavbeta3 PET imaging
-
Liu Z, Niu G, Shi J, Liu S, Wang F, Chen X (2009b) (68)Ga-labeled cyclic RGD dimers with Gly3 and PEG4 linkers: promising agents for tumor integrin alphavbeta3 PET imaging. Eur J Nucl Med Mol Imaging 36:947-957
-
(2009)
Eur J Nucl Med Mol Imaging
, vol.36
, pp. 947-957
-
-
Liu, Z.1
Niu, G.2
Shi, J.3
Liu, S.4
Wang, F.5
Chen, X.6
-
13
-
-
60549098667
-
Dual integrin and gastrin-releasing peptide receptor targeted tumor imaging using18F-labeled PEGylated RGD-bombesin heterodimer 18F-FBPEG3-Glu-RGD- BBN
-
Liu Z, Yan Y, Chin FT, Wang F, Chen X (2009c) Dual integrin and gastrin-releasing peptide receptor targeted tumor imaging using 18F-labeled PEGylated RGD-bombesin heterodimer 18F-FBPEG3-Glu-RGD-BBN. J Med Chem 52:425-432
-
(2009)
J Med Chem
, vol.52
, pp. 425-432
-
-
Liu, Z.1
Yan, Y.2
Chin, F.T.3
Wang, F.4
Chen, X.5
-
14
-
-
67650093751
-
Small-animal PET of tumors with (64)Cu-labeled RGD-bombesin heterodimer
-
Liu Z, Li ZB, Cao Q, Liu S, Wang F, Chen X (2009d) Small-animal PET of tumors with (64)Cu-labeled RGD-bombesin heterodimer. J Nucl Med 50:1168-1177
-
(2009)
J Nucl Med
, vol.50
, pp. 1168-1177
-
-
Liu, Z.1
Li, Z.B.2
Cao, Q.3
Liu, S.4
Wang, F.5
Chen, X.6
-
15
-
-
68949212307
-
(68)Ga-labeled NOTA-RGDBBN peptide for dual integrin and GRPR-targeted tumor imaging
-
Liu Z, Niu G, Wang F, Chen X (2009e) (68)Ga-labeled NOTA-RGDBBN peptide for dual integrin and GRPR-targeted tumor imaging. Eur J Nucl Med Mol Imaging 36:1483-1494
-
(2009)
Eur J Nucl Med Mol Imaging
, vol.36
, pp. 1483-1494
-
-
Liu, Z.1
Niu, G.2
Wang, F.3
Chen, X.4
-
16
-
-
66149176919
-
18F, 64Cu, and 68 Ga labeled RGD-bombesin heterodimeric peptides for PET imaging of breast cancer
-
Liu Z, Yan Y, Liu S, Wang F, Chen X (2009f) 18F, 64Cu, and 68 Ga labeled RGD-bombesin heterodimeric peptides for PET imaging of breast cancer. Bioconjug Chem 20:1016-1025
-
(2009)
Bioconjug Chem
, vol.20
, pp. 1016-1025
-
-
Liu, Z.1
Yan, Y.2
Liu, S.3
Wang, F.4
Chen, X.5
-
17
-
-
0032476812
-
Polyvalent interactions in biological systems: Implications for design and use of multivalent ligands and inhibitors
-
Mammen M, Choi S-K, Whitesides G (1998) Polyvalent interactions in biological systems: implications for design and use of multivalent ligands and inhibitors. Angew Chem 37:2755-2794
-
(1998)
Angew Chem
, vol.37
, pp. 2755-2794
-
-
Mammen, M.1
Choi, S.-K.2
Whitesides, G.3
-
18
-
-
33845587544
-
A flexible method for preparation of peptide homo- and heterodimers functionalized with affinity probes, chelating ligands, and latent conjugating groups
-
DOI 10.1002/bip.20570
-
Pillai R, Marinelli ER, Swenson RE (2006) A flexible method for preparation of peptide homo- and heterodimers functionalized with affinity probes, chelating ligands, and latent conjugating groups. Biopolymers 84:576-585 (Pubitemid 44935257)
-
(2006)
Biopolymers - Peptide Science Section
, vol.84
, Issue.6
, pp. 576-585
-
-
Pillai, R.1
Marinelli, E.R.2
Swenson, R.E.3
-
19
-
-
0037907532
-
Concomitant expression of several peptide receptors in neuroendocrine tumours: Molecular basis for in vivo multireceptor tumour targeting
-
Reubi JC, Waser B (2003) Concomitant expression of several peptide receptors in neuroendocrine tumours: molecular basis for in vivo multireceptor tumour targeting. Eur J Nucl Med Mol Imaging 30:781-793 (Pubitemid 36612963)
-
(2003)
European Journal of Nuclear Medicine and Molecular Imaging
, vol.30
, Issue.5
, pp. 781-793
-
-
Reubi, J.C.1
Waser, B.2
-
20
-
-
0030447479
-
Melanotropic peptide-conjugated beads for microscopic visualization and characterization of melanoma melanotropin receptors
-
DOI 10.1073/pnas.93.24.13715
-
Sharma SD, Jiang J, Hadley ME, Bentley DL, Hruby VJ (1996) Melanotropic peptide-conjugated beads for microscopic visualization and characterization of melanoma melanotropin receptors. Proc Natl Acad Sci USA 93:13715-13720 (Pubitemid 26424185)
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, Issue.24
, pp. 13715-13720
-
-
Sharma, S.D.1
Jiang, J.2
Hadley, M.E.3
Bentley, D.L.4
Hruby, V.J.5
-
21
-
-
24044486898
-
A distinct strategy to generate high-affinity peptide binders to receptor tyrosine kinases
-
DOI 10.1093/protein/gzi049
-
Shrivastava A, von Wronski MA, Sato AK et al (2005) A distinct strategy to generate high-affinity peptide binders to receptor tyrosine kinases. Protein Eng Des Sel 18:417-424 (Pubitemid 41219888)
-
(2005)
Protein Engineering, Design and Selection
, vol.18
, Issue.9
, pp. 417-424
-
-
Shrivastava, A.1
Von Wronski, M.A.2
Sato, A.K.3
Dransfield, D.T.4
Sexton, D.5
Bogdan, N.6
Pillai, R.7
Nanjappan, P.8
Song, B.9
Marinelli, E.10
DeOliveira, D.11
Luneau, C.12
Devlin, M.13
Muruganandam, A.14
Abujoub, A.15
Connelly, G.16
Wu, Q.L.17
Conley, G.18
Chang, Q.19
Tweedle, M.F.20
Ladner, R.C.21
Swenson, R.E.22
Nunn, A.D.23
more..
-
23
-
-
35948945504
-
Adventures in multivalency, the Harry S. Fischer memorial lecture CMR 2005; Evian, France
-
Tweedle MF (2006) Adventures in multivalency, the Harry S. Fischer memorial lecture CMR 2005; Evian, France. Contrast Media Mol Imaging 1:2-9
-
(2006)
Contrast Media Mol Imaging
, vol.1
, pp. 2-9
-
-
Tweedle, M.F.1
-
24
-
-
67651102575
-
Peptide-targeted diagnostics and radiotherapeutics
-
Tweedle MF (2009) Peptide-targeted diagnostics and radiotherapeutics. Acc Chem Res 42:958-968
-
(2009)
Acc Chem Res
, vol.42
, pp. 958-968
-
-
Tweedle, M.F.1
-
25
-
-
34848873423
-
Multivalency - A way to enhance binding avidities and bioactivity - Preliminary applications to EPO
-
DOI 10.1002/psc.794
-
Vadas O, Rose K (2007) Multivalency-a way to enhance binding avidities and bioactivity-preliminary applications to EPO. J Pept Sci 13:581-587 (Pubitemid 47490323)
-
(2007)
Journal of Peptide Science
, vol.13
, Issue.9
, pp. 581-587
-
-
Vadas, O.1
Rose, K.2
-
26
-
-
41049098044
-
Heterobivalent ligands crosslink multiple cell-surface receptors: The human melanocortin- 4 and delta-opioid receptors
-
Vagner J, Xu L, Handl HL et al (2008) Heterobivalent ligands crosslink multiple cell-surface receptors: the human melanocortin- 4 and delta-opioid receptors. Angew Chem Int Ed Engl 47:1685-1688
-
(2008)
Angew Chem Int Ed Engl
, vol.47
, pp. 1685-1688
-
-
Vagner, J.1
Xu, L.2
Handl, H.L.3
-
27
-
-
27944457471
-
64Cu-labeled tetrameric RGD peptide
-
Wu Y, Zhang X, Xiong Z et al (2005) microPET imaging of glioma integrin {alpha}v{beta}3 expression using (64)Cu-labeled tetrameric RGD peptide. J Nucl Med 46:1707-1718 (Pubitemid 46211595)
-
(2005)
Journal of Nuclear Medicine
, vol.46
, Issue.10
, pp. 1707-1718
-
-
Wu, Y.1
Zhang, X.2
Xiong, Z.3
Cheng, Z.4
Fisher, D.R.5
Liu, S.6
Gambhir, S.S.7
Chen, X.8
-
28
-
-
34548580354
-
18F-FPRGD4)
-
DOI 10.2967/jnumed.107.040816
-
Wu Z, Li ZB, Chen K et al (2007) microPET of tumor integrin alphavbeta3 expression using 18F-labeled PEGylated tetrameric RGD peptide (18F-FPRGD4). J Nucl Med 48:1536-1544 (Pubitemid 47397404)
-
(2007)
Journal of Nuclear Medicine
, vol.48
, Issue.9
, pp. 1536-1544
-
-
Wu, Z.1
Li, Z.-B.2
Chen, K.3
Cai, W.4
He, L.5
Chin, F.T.6
Li, F.7
Chen, X.8
-
29
-
-
68849122747
-
Enhanced targeting with heterobivalent ligands
-
Xu L, Vagner J, Josan J et al (2009) Enhanced targeting with heterobivalent ligands. Mol Cancer Ther 8:2356-2365
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 2356-2365
-
-
Xu, L.1
Vagner, J.2
Josan, J.3
-
30
-
-
33645698508
-
Design, synthesis, and evaluation of near infrared fluorescent multimeric RGD peptides for targeting tumors
-
Ye Y, Bloch S, Xu B, Achilefu S (2006) Design, synthesis, and evaluation of near infrared fluorescent multimeric RGD peptides for targeting tumors. J Med Chem 49:2268-2275
-
(2006)
J Med Chem
, vol.49
, pp. 2268-2275
-
-
Ye, Y.1
Bloch, S.2
Xu, B.3
Achilefu, S.4
-
31
-
-
65649117755
-
Peptides for tumour therapy and diagnosis: Current status and future directions
-
Zaccaro L, Del Gatto A, Pedone C, Saviano M (2009) Peptides for tumour therapy and diagnosis: current status and future directions. Curr Med Chem 16:780-795
-
(2009)
Curr Med Chem
, vol.16
, pp. 780-795
-
-
Zaccaro, L.1
Del Gatto, A.2
Pedone, C.3
Saviano, M.4
-
32
-
-
33646415036
-
Quantitative PET imaging of tumor integrin alphavbeta3 expression with 18F-FRGD2
-
Zhang X, Xiong Z, Wu Y et al (2006) Quantitative PET imaging of tumor integrin alphavbeta3 expression with 18F-FRGD2. J Nucl Med 47:113-121
-
(2006)
J Nucl Med
, vol.47
, pp. 113-121
-
-
Zhang, X.1
Xiong, Z.2
Wu, Y.3
|