Neuroprotective effects of melatonin on the nigrostriatal dopamine system in the zitter rat

Neuroscience Letters

Volumn 506, Issue 1, 2012, Pages 79-83

  Hashimoto, Ken ichi ^a   Ueda, Shuichi ^a   Ehara, Ayuka ^a   Sakakibara, Shin ichi ^b   Yoshimoto, Kanji ^c   Hirata, Koichi ^a  

^a DOKKYO MEDICAL UNIVERSITY   (Japan)

^b WASEDA UNIVERSITY   (Japan)

^c KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

Author keywords

Degeneration; Dopamine; Melatonin; Neuroprotection; Oxidative stress; PD model

Indexed keywords

CATALASE; COPPER ZINC SUPEROXIDE DISMUTASE; DOPAMINE; DRINKING WATER; GLUTATHIONE PEROXIDASE 1; INTERLEUKIN 1BETA; MANGANESE SUPEROXIDE DISMUTASE; MELATONIN; MESSENGER RNA; SUPEROXIDE; TUMOR NECROSIS FACTOR ALPHA; TYROSINE 3 MONOOXYGENASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN NERVE CELL; CAUDATE NUCLEUS; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINERGIC SYSTEM; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; IN VIVO STUDY; LONG TERM CARE; MALE; MESENCEPHALON; NERVE DEGENERATION; NEUROCHEMISTRY; NEUROPROTECTION; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PUTAMEN; RAT; SUBSTANTIA NIGRA PARS COMPACTA; UPREGULATION; WEANING; ZITTER RAT;

3,4-DIHYDROXYPHENYLACETIC ACID; ANIMALS; CORPUS STRIATUM; CYTOKINES; DISEASE MODELS, ANIMAL; DOPAMINE; DOPAMINERGIC NEURONS; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; MELATONIN; MESENCEPHALON; NERVE TISSUE PROTEINS; NEUROPROTECTIVE AGENTS; RATS; RATS, MUTANT STRAINS; RATS, SPRAGUE-DAWLEY; STRIATONIGRAL DEGENERATION; TYROSINE 3-MONOOXYGENASE;

EID: 84855205227     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2011.10.053     Document Type: Article

References (29)

1. Acuna-Castroviejo D., Coto-Montes A., Monti M.G., Ortiz G.G., Reiter R.J. Melatonin is protective against MPTP-induced striatal and hippocampal lesions. Life Sci. 1997, 60:PL23-PL29.
2. Antolin I., Mayo J.C., Sainz R.M., de los Angeles del Brio M., Herrera F., Martin V., Rodriguez C. Protective effect of melatonin in a chronic experimental model of Parkinson's disease. Brain Res. 2002, 943:163-173.
3. Bonnefont-Rousselot D., Collin F., Jore D., Gardes-Albert M. Reaction mechanism of melatonin oxidation by reactive oxygen species in vitro. J. Pineal Res. 2011, 50:328-335.
4. Dong Y., Benveniste F.N. Immune function of astrocytes. Glia 2001, 36:180-190.
5. Ehara A., Ueda S. Application of Fluoro-Jade C in acute and chronic neurodegeneration models: utilities and staining differences. Acta Histochem. Cytochem. 2009, 42:171-179.
6. Galano A., Tan D.X., Reiter R.J. Melatonin as a natural ally against oxidative stress: a physicochemical examination. J. Pineal Res. 2011, 51:1-16.
7. Gomi H., Ueno I., Yamanouchi K. Antioxidant enzymes in the brain of zitter rats: abnormal metabolism of oxygen species and its relevance to pathogenic changes in the brain of zitter rats with genetic spongiform encephalopathy. Brain Res. 1994, 653:66-72.
8. Hald A., Lotharius J. Oxidative stress and inflammation in Parkinson's disease: is there a causal link?. Exp. Neurol. 2005, 193:279-290.
9. Jenner P., Dexter D.T., Sian J., Schapira A.H.V., Marsden C.D. Oxidative stress as a cause of nigral cell death in Parkinson's disease and incidental Lewy body disease. Ann. Neurol. 1992, 32:S82-S87.
10. Kadowaki T., Nakadate K., Sakakibara S., Hirata K., Ueda S. Expression of Iba1 protein in microglial cells of zitter mutant rat. Neurosci. Lett. 2007, 411:26-31.
11. Kuramoto T., Kitada K., Inui T., Sasaki Y., Ito K., Hase T., Kawaguchi S., Ogawa Y., Nakao K., Barsh G.S., Nagano M., Ushijima T., Serikawa T. Attractin/mahogany/zitter plays a critical role in myelination of the central nervous system. Proc. Natl. Acad. Sci. U.S.A. 2001, 98:559-564.
12. Lu X.-Y., Gunn T.M., Shieh K.-R., Barsh G.S., Akil H., Watson S.J. Distribution of mahogany/attractin mRNA in the rat central nervous system. FEBS Lett. 1999, 462:101-107.
13. Mills K.H.G., Dunne A. IL-1, master mediator of initiator of inflammation. Nat. Med. 2009, 15:1363-1364.
14. Nakadate K., Sakakibara S., Ueda S. Attractin/mahogany protein expression in the rodent central nervous system. J. Comp. Neurol. 2008, 508:94-111.
15. Olanow C.W., Youdim M.B.H. Iron and neurodegeneration: prospects for neuroprotection. Neurodegeneration and Neuroprotection in Parkinson's Disease 1996, 55-67. Academic Press, London. C.W. Olanow, P. Jenner, M.B.H. Youdim (Eds.).
16. Paz J., Yao H., Lim H.S., Lu X.-Y., Zhang W. The neuroprotective role of attractin in neurodegeneration. Neurobiol. Aging 2007, 28:1446-1456.
17. Peinnequin A., Mouret C., Birot O., Alonso A., Mathieu J., Clarencon D., Agay D., Chancerelle Y., Multon E. Rat pro-inflammatory cytokine and cytokine related mRNA quantification by real-time polymerase chain reaction using SYBR green. BMC Immunol. 2004, 5:3.
18. Reiter R.J. Oxidative damage in the central nervous system: protection by melatonin. Prog. Neurobiol. 1998, 56:359-384.
19. Rodriguez C., Mayo J.C., Sainz R.M., Antolin I., Herrera F., Martin V., Reiter R.J. Regulation of antioxidant enzymes: a significant role for melatonin. J. Pineal Res. 2004, 36:1-9.
20. Sakakibara S., Nakadate K., Ookawara S., Ueda S. Non-cell autonomous impairment of oligodendrocyte differentiation precedes CNS degeneration in the zitter rat: implications of macrophage/microglial activation in the pathogenesis. BMC Neurosci. 2008, 9:35.
21. Sharma R., McMillan C.R., Tenn C.C., Niles L. Physiological neuroprotection by melatonin in a 6-hydroxydopamine model of Parkinson's disease. Brain Res. 2006, 1068:230-236.
22. Tan D.X., Manchester L.C., Hardeland R., Lopez-Burillo S., Mayo J.C., Sainz R.M., Reiter R.J. Melatonin: a hormone, a tissue factor, an autocoid, a paracoid, and an oxidant vitamin. J. Pineal Res. 2003, 34:75-78.
23. Teismann P., Schulz J.B. Cellular pathology of Parkinson's disease: astrocytes: microglia and inflammation. Cell Tissue Res. 2004, 318:149-161.
24. Thomas B., Mohanakumar K.P. Melatonin protects against oxidative stress caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the mouse nigrostriatum. J. Pineal Res. 2004, 36:25-32.
25. Tomas-Zapico C., Coto-Montes A. A proposed mechanism to explain the stimulatory effects of melatonin on antioxidative enzymes. J. Pineal Res. 2005, 29:99-104.
26. Ueda S., Aikawa M., Ishizuya-Oka A., Yamaoka S., Koibuchi N., Yoshimoto K. Age-related dopamine deficiency in the mesostriatal dopamine system of zitter mutant rats: regional fiber vulnerability in the striatum and the olfactory tubercle. Neuroscience 2000, 95:389-398.
27. Ueda S., Sakakibara S., Kadowaki T., Naitoh T., Hirata K., Yoshimoto K. Chronic treatment with melatonin attenuates serotonergic degeneration in the striatum and olfactory tubercle of zitter mutant rats. Neurosci. Lett. 2008, 448:212-216.
28. Ueda S., Sakakibara S., Nakadate K., Noda T., Shinoda M., Joyce J.N. Degeneration of dopaminergic neurons in the substantia nigra of zitter mutant rat and protection by chronic intake of vitamin E. Neurosci. Lett. 2005, 380:252-256.
29. Ueda S., Sakakibara S., Watanabe E., Yoshimoto K., Koibuchi N. Vulnerability of monoaminergic neurons in the brainstem of the zitter rat in oxidative stress. Prog. Brain Res. 2002, 136:293-302.