메뉴 건너뛰기




Volumn 11, Issue , 2011, Pages

Multi-tyrosine kinase inhibitors in preclinical studies for pediatric CNS AT/RT: Evidence for synergy with Topoisomerase-I inhibition

Author keywords

[No Author keywords available]

Indexed keywords

7 ETHYL 10 HYDROXYCAMPTOTHECIN; FIBROBLAST GROWTH FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IRINOTECAN; PLATELET DERIVED GROWTH FACTOR; SORAFENIB; STROMAL CELL DERIVED FACTOR 1; SUNITINIB; VASCULOTROPIN;

EID: 84855182679     PISSN: None     EISSN: 14752867     Source Type: Journal    
DOI: 10.1186/1475-2867-11-44     Document Type: Article
Times cited : (20)

References (46)
  • 1
    • 79955724848 scopus 로고    scopus 로고
    • Atypical teratoid/rhabdoid tumor: short clinical description and insight into possible mechanism of the disease
    • 10.1111/j.1468-1331.2010.03277.x, 21159066
    • Bikowska B, Grajkowska W, Jozwiak J. Atypical teratoid/rhabdoid tumor: short clinical description and insight into possible mechanism of the disease. Eur J Neurol 2011, 18:813-818. 10.1111/j.1468-1331.2010.03277.x, 21159066.
    • (2011) Eur J Neurol , vol.18 , pp. 813-818
    • Bikowska, B.1    Grajkowska, W.2    Jozwiak, J.3
  • 2
    • 33646104935 scopus 로고    scopus 로고
    • Molecular genetics of atypical teratoid/rhabdoid tumor
    • 10.3171/foc.2006.20.4.6, 16819809
    • Biegel JA. Molecular genetics of atypical teratoid/rhabdoid tumor. Neurosurg Focus 2006, 20:E11. 10.3171/foc.2006.20.4.6, 16819809.
    • (2006) Neurosurg Focus , vol.20
    • Biegel, J.A.1
  • 6
    • 33746808098 scopus 로고    scopus 로고
    • Members of the hSWI/SNF chromatin remodeling complex associate with and are phosphorylated by protein kinase B/Akt
    • 10.1038/sj.onc.1209496, 16568092
    • Foster KS, McCrary WJ, Ross JS, Wright CF. Members of the hSWI/SNF chromatin remodeling complex associate with and are phosphorylated by protein kinase B/Akt. Oncogene 2006, 25:4605-4612. 10.1038/sj.onc.1209496, 16568092.
    • (2006) Oncogene , vol.25 , pp. 4605-4612
    • Foster, K.S.1    McCrary, W.J.2    Ross, J.S.3    Wright, C.F.4
  • 7
    • 36849045765 scopus 로고    scopus 로고
    • Highly aggressive behavior of malignant rhabdoid tumor: a special reference to SMARCB1/INI1 gene alterations using molecular genetic analysis including quantitative real-time PCR
    • 10.1007/s00432-007-0223-z, 17486366
    • Kohashi K, Oda Y, Yamamoto H, Tamiya S, Izumi T, Ohta S, Taguchi T, Suita S, Tsuneyoshi M. Highly aggressive behavior of malignant rhabdoid tumor: a special reference to SMARCB1/INI1 gene alterations using molecular genetic analysis including quantitative real-time PCR. J Cancer Res Clin Oncol 2007, 133:817-824. 10.1007/s00432-007-0223-z, 17486366.
    • (2007) J Cancer Res Clin Oncol , vol.133 , pp. 817-824
    • Kohashi, K.1    Oda, Y.2    Yamamoto, H.3    Tamiya, S.4    Izumi, T.5    Ohta, S.6    Taguchi, T.7    Suita, S.8    Tsuneyoshi, M.9
  • 8
    • 33748100218 scopus 로고    scopus 로고
    • The tumor suppressor hSNF5/INI1 controls the differentiation potential of malignant rhabdoid cells
    • 10.1016/j.ejca.2006.03.028, 16908131
    • Albanese P, Belin MF, Delattre O. The tumor suppressor hSNF5/INI1 controls the differentiation potential of malignant rhabdoid cells. Eur J Cancer 2006, 42:2326-2334. 10.1016/j.ejca.2006.03.028, 16908131.
    • (2006) Eur J Cancer , vol.42 , pp. 2326-2334
    • Albanese, P.1    Belin, M.F.2    Delattre, O.3
  • 9
    • 53349122128 scopus 로고    scopus 로고
    • Establishment of atypical-teratoid/rhabdoid tumor (AT/RT) cell cultures from disseminated CSF cells: a model to elucidate biology and potential targeted therapeutics
    • 10.1007/s11060-008-9653-y, 18651103
    • Narendran A, Coppes L, Jayanthan A, Coppes M, Teja B, Bernoux D, George D, Strother D. Establishment of atypical-teratoid/rhabdoid tumor (AT/RT) cell cultures from disseminated CSF cells: a model to elucidate biology and potential targeted therapeutics. J Neurooncol 2008, 90:171-180. 10.1007/s11060-008-9653-y, 18651103.
    • (2008) J Neurooncol , vol.90 , pp. 171-180
    • Narendran, A.1    Coppes, L.2    Jayanthan, A.3    Coppes, M.4    Teja, B.5    Bernoux, D.6    George, D.7    Strother, D.8
  • 10
    • 34250012015 scopus 로고    scopus 로고
    • Antisense treatment of IGF-IR induces apoptosis and enhances chemosensitivity in central nervous system atypical teratoid/rhabdoid tumours cells
    • 10.1016/j.ejca.2007.03.003, 17446062
    • D'cunja J, Shalaby T, Rivera P, von Büren A, Patti R, Heppner FL, Arcaro A, Rorke-Adams LB, Phillips PC, Grotzer MA. Antisense treatment of IGF-IR induces apoptosis and enhances chemosensitivity in central nervous system atypical teratoid/rhabdoid tumours cells. Eur J Cancer 2007, 43:1581-1589. 10.1016/j.ejca.2007.03.003, 17446062.
    • (2007) Eur J Cancer , vol.43 , pp. 1581-1589
    • D'cunja, J.1    Shalaby, T.2    Rivera, P.3    von Büren, A.4    Patti, R.5    Heppner, F.L.6    Arcaro, A.7    Rorke-Adams, L.B.8    Phillips, P.C.9    Grotzer, M.A.10
  • 12
    • 41549108420 scopus 로고    scopus 로고
    • From single- to multi-target drugs in cancer therapy: when aspecificity becomes an advantage
    • 10.2174/092986708783503212, 18288997
    • Petrelli A, Giordano S. From single- to multi-target drugs in cancer therapy: when aspecificity becomes an advantage. Curr Med Chem 2008, 15:422-432. 10.2174/092986708783503212, 18288997.
    • (2008) Curr Med Chem , vol.15 , pp. 422-432
    • Petrelli, A.1    Giordano, S.2
  • 13
    • 70450197345 scopus 로고    scopus 로고
    • Sunitinib: a multitargeted receptor tyrosine kinase inhibitor in the era of molecular cancer therapies
    • 10.2165/11318860-000000000-00000, 19894779
    • Papaetis GS, Syrigos KN. Sunitinib: a multitargeted receptor tyrosine kinase inhibitor in the era of molecular cancer therapies. BioDrugs 2009, 23:377-389. 10.2165/11318860-000000000-00000, 19894779.
    • (2009) BioDrugs , vol.23 , pp. 377-389
    • Papaetis, G.S.1    Syrigos, K.N.2
  • 14
    • 70350772288 scopus 로고    scopus 로고
    • Tyrosine Kinase Inhibitors - A Review on Pharmacology, Metabolism and Side Effects
    • 10.2174/138920009788897975, 19689244
    • Hartmann JT, Haap M, Kopp HG, Lipp HP. Tyrosine Kinase Inhibitors - A Review on Pharmacology, Metabolism and Side Effects. Curr Drug Metab 2009, 10:470-481. 10.2174/138920009788897975, 19689244.
    • (2009) Curr Drug Metab , vol.10 , pp. 470-481
    • Hartmann, J.T.1    Haap, M.2    Kopp, H.G.3    Lipp, H.P.4
  • 15
    • 45849107634 scopus 로고    scopus 로고
    • Topoisomerase I inhibitors for the treatment of brain tumors
    • 10.1586/14737140.8.5.707, 18471044
    • Feun L, Savaraj N. Topoisomerase I inhibitors for the treatment of brain tumors. Expert Rev Anticancer Ther 2008, 8:707-716. 10.1586/14737140.8.5.707, 18471044.
    • (2008) Expert Rev Anticancer Ther , vol.8 , pp. 707-716
    • Feun, L.1    Savaraj, N.2
  • 16
    • 76549129820 scopus 로고    scopus 로고
    • Drug combination studies and their synergy quantification using the Chou-Talalay method
    • 10.1158/0008-5472.CAN-09-1947, 20068163
    • Chou TC. Drug combination studies and their synergy quantification using the Chou-Talalay method. Cancer Res 2010, 70:440-446. 10.1158/0008-5472.CAN-09-1947, 20068163.
    • (2010) Cancer Res , vol.70 , pp. 440-446
    • Chou, T.C.1
  • 17
    • 16844366650 scopus 로고    scopus 로고
    • Nuclear factor-kappaB inhibitors as sensitizers to anticancer drugs
    • 10.1038/nrc1588, 15803156
    • Nakanishi C, Toi M. Nuclear factor-kappaB inhibitors as sensitizers to anticancer drugs. Nat Rev Cancer 2005, 5:297-309. 10.1038/nrc1588, 15803156.
    • (2005) Nat Rev Cancer , vol.5 , pp. 297-309
    • Nakanishi, C.1    Toi, M.2
  • 20
    • 27744547739 scopus 로고    scopus 로고
    • Atypical teratoid rhabdoid tumors of childhood: diagnosis, treatment and challenges
    • 10.1586/14737140.5.5.907, 16221059
    • Strother D. Atypical teratoid rhabdoid tumors of childhood: diagnosis, treatment and challenges. Expert Rev Anticancer Ther 2005, 5:907-915. 10.1586/14737140.5.5.907, 16221059.
    • (2005) Expert Rev Anticancer Ther , vol.5 , pp. 907-915
    • Strother, D.1
  • 23
    • 43149087097 scopus 로고    scopus 로고
    • Successful outcome with tandem myeloablative chemotherapy and autologous peripheral blood stem cell transplants in a patient with atypical teratoid/rhabdoid tumor of the central nervous system
    • 10.1007/s11060-008-9553-1, 18317689
    • Gidwani P, Levy A, Goodrich J, Weidenheim K, Kolb EA. Successful outcome with tandem myeloablative chemotherapy and autologous peripheral blood stem cell transplants in a patient with atypical teratoid/rhabdoid tumor of the central nervous system. J Neurooncol 2008, 88:211-215. 10.1007/s11060-008-9553-1, 18317689.
    • (2008) J Neurooncol , vol.88 , pp. 211-215
    • Gidwani, P.1    Levy, A.2    Goodrich, J.3    Weidenheim, K.4    Kolb, E.A.5
  • 24
    • 33845712045 scopus 로고    scopus 로고
    • Atypical teratoid/rhabdoid tumor: the controversy behind radiation therapy
    • Squire SE, Chan MD, Marcus KJ. Atypical teratoid/rhabdoid tumor: the controversy behind radiation therapy. J Neurooncol 2007, 81:97-111.
    • (2007) J Neurooncol , vol.81 , pp. 97-111
    • Squire, S.E.1    Chan, M.D.2    Marcus, K.J.3
  • 25
    • 33644559052 scopus 로고    scopus 로고
    • Impact of radiotherapy for pediatric CNS atypical teratoid/rhabdoid tumor (single institute experience)
    • 10.1016/j.ijrobp.2005.10.001, 16406394
    • Chen YW, Wong TT, Ho DM, Huang PI, Chang KP, Shiau CY, Yen SH. Impact of radiotherapy for pediatric CNS atypical teratoid/rhabdoid tumor (single institute experience). Int J Radiat Oncol Biol Phys 2006, 64:1038-1043. 10.1016/j.ijrobp.2005.10.001, 16406394.
    • (2006) Int J Radiat Oncol Biol Phys , vol.64 , pp. 1038-1043
    • Chen, Y.W.1    Wong, T.T.2    Ho, D.M.3    Huang, P.I.4    Chang, K.P.5    Shiau, C.Y.6    Yen, S.H.7
  • 27
    • 0035137420 scopus 로고    scopus 로고
    • Comparative immunohistochemical study of insulin-like growth factor II and insulin-like growth factor receptor type 1 in pediatric brain tumors
    • 10.1007/s100240010112, 11200487
    • Ogino S, Kubo S, Abdul-Karim FW, Cohen ML. Comparative immunohistochemical study of insulin-like growth factor II and insulin-like growth factor receptor type 1 in pediatric brain tumors. Pediatr Dev Pathol 2001, 4:23-31. 10.1007/s100240010112, 11200487.
    • (2001) Pediatr Dev Pathol , vol.4 , pp. 23-31
    • Ogino, S.1    Kubo, S.2    Abdul-Karim, F.W.3    Cohen, M.L.4
  • 30
    • 27144502652 scopus 로고    scopus 로고
    • The role of Mcl-1 downregulation in the proapoptotic activity of the multikinase inhibitor BAY 43-9006
    • 10.1038/sj.onc.1208841, 16007148
    • Yu C, Bruzek LM, Meng XW, Gores GJ, Carter CA, Kaufmann SH, Adjei AA. The role of Mcl-1 downregulation in the proapoptotic activity of the multikinase inhibitor BAY 43-9006. Oncogene 2005, 24:6861-6869. 10.1038/sj.onc.1208841, 16007148.
    • (2005) Oncogene , vol.24 , pp. 6861-6869
    • Yu, C.1    Bruzek, L.M.2    Meng, X.W.3    Gores, G.J.4    Carter, C.A.5    Kaufmann, S.H.6    Adjei, A.A.7
  • 31
    • 42049091619 scopus 로고    scopus 로고
    • Unique biology of Mcl-1: therapeutic opportunities in cancer
    • 10.2174/156652408783769580, 18336294
    • Warr MR, Shore GC. Unique biology of Mcl-1: therapeutic opportunities in cancer. Curr Mol Med 2008, 8:138-147. 10.2174/156652408783769580, 18336294.
    • (2008) Curr Mol Med , vol.8 , pp. 138-147
    • Warr, M.R.1    Shore, G.C.2
  • 33
    • 75149180560 scopus 로고    scopus 로고
    • Sunitinib induces apoptosis and growth arrest of medulloblastoma tumor cells by inhibiting STAT3 and AKT signaling pathways
    • 10.1158/1541-7786.MCR-09-0220, 2808420, 20053726
    • Yang F, Jove V, Xin H, Hedvat M, Van Meter TE, Yu H. Sunitinib induces apoptosis and growth arrest of medulloblastoma tumor cells by inhibiting STAT3 and AKT signaling pathways. Mol Cancer Res 2010, 8:35-45. 10.1158/1541-7786.MCR-09-0220, 2808420, 20053726.
    • (2010) Mol Cancer Res , vol.8 , pp. 35-45
    • Yang, F.1    Jove, V.2    Xin, H.3    Hedvat, M.4    Van Meter, T.E.5    Yu, H.6
  • 35
    • 0029116438 scopus 로고
    • Efficacy of topoisomerase I inhibitors, topotecan and irinotecan, administered at low dose levels in protracted schedules to mice bearing xenografts of human tumors
    • 10.1007/BF00686188, 7634381
    • Houghton PJ, Cheshire PJ, Hallman JD, Lutz L, Friedman HS, Danks MK, Houghton JA. Efficacy of topoisomerase I inhibitors, topotecan and irinotecan, administered at low dose levels in protracted schedules to mice bearing xenografts of human tumors. Cancer Chemother Pharmacol 1995, 36:393-403. 10.1007/BF00686188, 7634381.
    • (1995) Cancer Chemother Pharmacol , vol.36 , pp. 393-403
    • Houghton, P.J.1    Cheshire, P.J.2    Hallman, J.D.3    Lutz, L.4    Friedman, H.S.5    Danks, M.K.6    Houghton, J.A.7
  • 37
    • 55849130720 scopus 로고    scopus 로고
    • Novel anti-angiogenic therapies for malignant gliomas
    • 10.1016/S1474-4422(08)70260-6, 19007739
    • Norden AD, Drappatz J, Wen PY. Novel anti-angiogenic therapies for malignant gliomas. Lancet Neurol 2008, 7:1152-1160. 10.1016/S1474-4422(08)70260-6, 19007739.
    • (2008) Lancet Neurol , vol.7 , pp. 1152-1160
    • Norden, A.D.1    Drappatz, J.2    Wen, P.Y.3
  • 38
    • 61449210864 scopus 로고    scopus 로고
    • Experience with irinotecan for the treatment of malignant glioma
    • 2718962, 18784279
    • Vredenburgh JJ, Desjardins A, Reardon DA, Friedman HS. Experience with irinotecan for the treatment of malignant glioma. Neuro Oncol 2009, 11:80-91. 2718962, 18784279.
    • (2009) Neuro Oncol , vol.11 , pp. 80-91
    • Vredenburgh, J.J.1    Desjardins, A.2    Reardon, D.A.3    Friedman, H.S.4
  • 40
    • 0036924112 scopus 로고    scopus 로고
    • Irinotecan: mechanisms of tumor resistance and novel strategies for modulating its activity
    • 10.1093/annonc/mdf337, 12453851
    • Xu Y, Villalona-Calero MA. Irinotecan: mechanisms of tumor resistance and novel strategies for modulating its activity. Ann Oncol 2002, 13:1841-1851. 10.1093/annonc/mdf337, 12453851.
    • (2002) Ann Oncol , vol.13 , pp. 1841-1851
    • Xu, Y.1    Villalona-Calero, M.A.2
  • 41
    • 0032508414 scopus 로고    scopus 로고
    • NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation
    • Wang CY, Mayo MW, Korneluk RG, Goeddel DV, Baldwin AS. NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science 1998, 281:1680-1683.
    • (1998) Science , vol.281 , pp. 1680-1683
    • Wang, C.Y.1    Mayo, M.W.2    Korneluk, R.G.3    Goeddel, D.V.4    Baldwin, A.S.5
  • 42
    • 2542449068 scopus 로고    scopus 로고
    • Enhanced chemosensitivity to irinotecan by RNA interference-mediated down-regulation of the nuclear factor-kappaB p65 subunit
    • 10.1158/1078-0432.CCR-03-0366, 15161687
    • Guo J, Verma UN, Gaynor RB, Frenkel EP, Becerra CR. Enhanced chemosensitivity to irinotecan by RNA interference-mediated down-regulation of the nuclear factor-kappaB p65 subunit. Clin Cancer Res 2004, 10:3333-3341. 10.1158/1078-0432.CCR-03-0366, 15161687.
    • (2004) Clin Cancer Res , vol.10 , pp. 3333-3341
    • Guo, J.1    Verma, U.N.2    Gaynor, R.B.3    Frenkel, E.P.4    Becerra, C.R.5
  • 44
    • 67849096609 scopus 로고    scopus 로고
    • Sorafenib inhibits nuclear factor kappa B, decreases inducible nitric oxide synthase and cyclooxygenase-2 expression, and restores working memory in APPswe mice
    • 10.1016/j.neuroscience.2009.05.019, 19447162
    • Echeverria V, Burgess S, Gamble-George J, Zeitlin R, Lin X, Cao C, Arendash GW. Sorafenib inhibits nuclear factor kappa B, decreases inducible nitric oxide synthase and cyclooxygenase-2 expression, and restores working memory in APPswe mice. Neuroscience 2009, 162:1220-1231. 10.1016/j.neuroscience.2009.05.019, 19447162.
    • (2009) Neuroscience , vol.162 , pp. 1220-1231
    • Echeverria, V.1    Burgess, S.2    Gamble-George, J.3    Zeitlin, R.4    Lin, X.5    Cao, C.6    Arendash, G.W.7
  • 45
    • 51649109943 scopus 로고    scopus 로고
    • Chemotherapeutic drugs and human tumor cells cytokine network
    • 10.1002/ijc.23732, 2574811, 18697197
    • Levina V, Su Y, Nolen B, Liu X, Gordin Y, Lee M, Lokshin A, Gorelik E. Chemotherapeutic drugs and human tumor cells cytokine network. Int J Cancer 2008, 123:2031-2040. 10.1002/ijc.23732, 2574811, 18697197.
    • (2008) Int J Cancer , vol.123 , pp. 2031-2040
    • Levina, V.1    Su, Y.2    Nolen, B.3    Liu, X.4    Gordin, Y.5    Lee, M.6    Lokshin, A.7    Gorelik, E.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.