Histological predictors for renal prognosis in diabetic nephropathy in diabetes mellitus type 2 patients with overt proteinuria

Nephrology

Volumn 17, Issue 1, 2012, Pages 68-75

  Okada, Tomonari ^a   Nagao, Toshitaka ^a   Matsumoto, Hiroshi ^a   Nagaoka, Yume ^a   Wada, Toshikazu ^a   Nakao, Toshiyuki ^a  

^a TOKYO MEDICAL UNIVERSITY   (Japan)

Author keywords

diabetes mellitus type 2; diabetic nephropathy; nodular lesion; proteinuria; renal biopsy

Indexed keywords

ALBUMIN; ANGIOTENSIN RECEPTOR ANTAGONIST; CALCIUM CHANNEL BLOCKING AGENT; CREATININE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ERYTHROPOIETIN; HEMOGLOBIN; HEMOGLOBIN A1C; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INSULIN; ORAL ANTIDIABETIC AGENT;

ADULT; AGED; ALBUMIN BLOOD LEVEL; ARTICLE; ATROPHY; CELL EXPANSION; CREATININE BLOOD LEVEL; DIABETIC NEPHROPATHY; DISEASE CLASSIFICATION; FEMALE; FOLLOW UP; GLOMERULOSCLEROSIS; HEMOGLOBIN BLOOD LEVEL; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; INSULIN TREATMENT; KIDNEY BIOPSY; KIDNEY FIBROSIS; KIDNEY INTERSTITIUM; KIDNEY NECROSIS; MAJOR CLINICAL STUDY; MALE; MESANGIUM CELL; NON INSULIN DEPENDENT DIABETES MELLITUS; OUTCOME ASSESSMENT; PREDICTIVE VALUE; PRIORITY JOURNAL; PROGNOSIS; PROTEINURIA; RETROSPECTIVE STUDY; SCORING SYSTEM; SYSTOLIC BLOOD PRESSURE;

AGED; BIOPSY; DIABETES MELLITUS, TYPE 2; DIABETIC NEPHROPATHIES; FEMALE; GLOMERULAR MESANGIUM; HISTOLOGICAL TECHNIQUES; HUMANS; KIDNEY FUNCTION TESTS; MALE; MIDDLE AGED; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; PROTEINURIA; RENAL DIALYSIS; RETROSPECTIVE STUDIES; RISK FACTORS; SEVERITY OF ILLNESS INDEX; SURVIVAL RATE;

EID: 84855182259     PISSN: 13205358     EISSN: 14401797     Source Type: Journal    
DOI: 10.1111/j.1440-1797.2011.01525.x     Document Type: Article

References (31)

1. Bader R, Bader H, Grund KE, Mackensen-Haen S, Christ H, Bohle A,. Structure and function of the kidney in diabetic glomerulosclerosis, correlations between morphological and functional parameters. Pathol. Res. Pract. 1980; 167: 204-16. (Pubitemid 10081929)
2. Mauer SM, Steffes MW, Ellis EN, Sutherland DER, Brown DM, Goetz FC,. Structural-functional relationships in diabetic nephropathy. J. Clin. Invest. 1984; 74: 1143-55. (Pubitemid 15210185)
3. Suzuki Y, Ueno H, Hayashi H, et al,. A light microscopic study of glomerulosclerosis in Japanese patients with noninsulin-dependent diabetes mellitus: The relationships between clinical and histological features. Clin. Nephrol. 1994; 42: 155-62. (Pubitemid 24287749)
4. Matsumae T, Jimi S, Uesugi N, Takebayashi S, Naito S,. Clinical and morphometrical interrelationships in patients with overt nephropathy induced by non-insulin-dependent diabetes mellitus. Nephron 1999; 81: 41-8. (Pubitemid 29041715)
5. White KE, Bilous RW, for the collaborative study group. Type 2 diabetic patients with nephropathy show structural-functional relationships that are similar to type 1 disease. J. Am. Soc. Nephrol. 2000; 11: 1667-73.
6. Taft JL, Nolan CJ, Yeung SP, Hewiston TD, Martin FIR,. Clinical and histological correlations of decline in renal function in diabetic patients with proteinuria. Diabetes 1994; 43: 1046-51. (Pubitemid 24230711)
7. Fioretto P, Sterres MW, Suthrland DER, Mauer M,. Sequential renal biopsies in insulin-dependent diabetic patients: Structural factors associated with clinical progression. Kidney Int. 1995; 48: 1929-35.
8. Cordonnier DJ, Pinel N, Barro C, et al,. Expansion of cortical interstitium is limited by converting enzyme inhibition in type 2 diabetic patients with glomerulosclerosis. J. Am. Soc. Nephrol. 1999; 10: 1253-63. (Pubitemid 29246990)
9. Perrin NESS, Torbjörnsdotter TB, Jaremko GA, Berg UB,. The course of diabetic glomerulopthy in patients with type 1 diabetes: A 6-year follow-up with serial biopsies. Kidney Int. 2006; 69: 699-705. (Pubitemid 43237639)
10. Østerby R, Gall MA, Schmitz A, Nielsen FS, Nyberg G, Parving HH,. Glomerular structure and function in proteinuric type 2 (non-insulin-dependent) diabetic patients. Diabetologia 1993; 36: 1064-70. (Pubitemid 23288777)
11. Ruggenenti P, Gambara V, Perna A, Bertani T, Remuzzi G,. The nephropathy of non-insulin-dependent diabetes: Predictors of outcome relative to diverse patterns of renal injury. J. Am. Soc. Nephrol. 1998; 9: 2336-43. (Pubitemid 28543812)
12. Bohle A, Wehrmann O, Bogenschütz O, Batz C, Müller CA,. The pathogenesis of chronic renal failure in diabetic nephropathy, investigation of 488 cases in diabetic glomerulosclerosis. Pathol. Res. Pract. 1991; 187: 251-9.
13. Heaf JG, Løkkegaard H, Larsen S,. The relative prognosis of nodular and diffuse diabetic nephropathy. Scand. J. Urol. Nephrol. 2001; 35: 233-8. (Pubitemid 32656040)
14. Hong D, Zheng T, Jia-quing S, Jian W, Zhi-hong L, Lei-shi L,. Nodular glomerular lesion: A later stage of diabetic nephropathy? Diabetes Res. Clin. Pract. 2007; 78: 189-95. (Pubitemid 47451535)
15. Shoji T, Kanda T, Nakamura H, et al,. Are glomerular lesions alternatives to microalbuminuria in predicting later progression of diabetic nephropathy? Clin. Nephrol. 1996; 45: 367-71. (Pubitemid 26187131)
16. Tervaert TWC, Mooyaart AL, Amann K, et al,. Pathologic classification of diabetic nephropathy. J. Am. Soc. Nephrol. 2010; 21: 556-63.
17. Matsuo S, Imai E, Horio M, et al,. Revised equations for estimated GFR from serum creatinine in Japan. Am. J. Kidney Dis. 2009; 53: 982-92.
18. Schwartz MM, Lewis EJ, Leonard-Martin T, Lewis JB, Batlle D, and the collaborative study group. Renal pathology patterns in type 2 diabetes mellitus: Relationships with retinopathy. Nephrol. Dial. Transplant. 1998; 13: 2547-52. (Pubitemid 28445867)
19. Gellman DD, Pirani CL, Soothill JF, Muehrcke RC, Mark RM,. Diabetic nephropathy: A clinical and pathologic study based on renal biopsies. Medicine 1959; 38: 321-67.
20. Okada T, Matsumoto H, Nakao T, et al,. Relationships of renal lesions with urinary protein excretion in patients with overt diabetic nephropathy. Jpn. J. Nephrol. 1999; 41: 475-85.
21. Morita T, Yamamoto T, Churg J,. Mesangiolyis: An update. Am. J. Kidney Dis. 1998; 31: 559-73.
22. Nakagawa T, Sato W, Glushakova O, et al,. Diabetic endothelial nitric oxide synthase knockout mice develop advanced diabetic nephropathy. J. Am. Soc. Nephrol. 2007; 18: 539-50. (Pubitemid 46193319)
23. Morita T, Yamada Y,. The cortical distribution pattern of diabetic glomerulopathy. Diabetologia 1986; 29: 673.
24. Hovind P, Rossing P, Tarnow L, Toft H, Parving J, Parving HH,. Remission of nephrotic-range albuminuria in type 1 diabetic patients. Diabetes Care 2001; 24: 1972-7. (Pubitemid 33716511)
25. Haraguchi K, Hara S, Ubara Y, et al,. Complete remission of diabetic nephropathy in a type 1 diabetic patient with near-nephrotic range proteinuria and reduced renal function. Diabet. Res. Clin. Pract. 2009; 83: 295-9.
26. Myers DI, Poole LJ, Imam K, Scheel PJ, Eustace JA,. Renal artery stenosis by three-dimensional magnetic resonance angiography in type 2 diabetes with uncontrolled hypertension and chronic renal insufficiency: Prevalence and effect on renal function. Am. J. Kidney Dis. 2003; 41: 351-9. (Pubitemid 36152453)
27. Ueno M, Kawashima S, Nishi S, et al,. Tubulointerstitial lesions in non-insulin dependent diabetes mellitus. Kidney Int. 1997; 52 (Suppl 63): S191-S194. (Pubitemid 28020468)
28. Zeisberg M, Neilson EG,. Mechanisms of tubulointerstitial fibrosis. J. Am. Soc. Nephrol. 2010; 21: 1819-34.
29. Fine LG, Norman JT,. Chronic hypoxia as a mechanism of progression of chronic kidney diseases: From hypothesis to novel therapeutics. Kidney Int. 2008; 74: 867-72.
30. Keane WF, Brenner BM, De Zeeuw D, et al,. The risk of developing end-stage renal disease in patients with type 2 diabetes and nephropathy: The RENAAL study. Kidney Int. 2003; 63: 1499-507. (Pubitemid 36350016)
31. Rossing K, Christensen PK, Hovind P, Tarnow L, Rossing P, Parving HH,. Progression of nephropathy in type 2 diabetic patients. Kidney Int. 2004; 66: 1596-605. (Pubitemid 39298395)