Cytokine response to diabetic ketoacidosis (DKA) in children with type 1 diabetes (T1DM)

Endocrine Journal

Volumn 58, Issue 12, 2011, Pages 1045-1053

  Karavanaki, Kyriaki ^a   Karanika, Evangelia ^a   Georga, Soultana ^a   Bartzeliotou, Anastasia ^b   Tsouvalas, Manolis ^a   Konstantopoulos, Ilias ^a   Fotinou, Aspasia ^c   Papassotiriou, Ioannis ^b   Karayianni, Christina ^a  

^a UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^b AGHIA SOPHIA CHILDREN S HOSPITAL   (Greece)

^c P AND A KYRIAKOU CHILDREN S HOSPITAL   (Greece)

Author keywords

Cellular activation; Cytokines; Ketoacidosis; Type 1 diabetes mellitus

Indexed keywords

C REACTIVE PROTEIN; GROWTH HORMONE; HYDROCORTISONE; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 6; INTERLEUKIN 8; TUMOR NECROSIS FACTOR ALPHA;

ADOLESCENT; ARTICLE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; CYTOKINE RESPONSE; DIABETIC KETOACIDOSIS; DISEASE SEVERITY; FEMALE; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; LEUKOCYTE COUNT; MALE; PRESCHOOL CHILD; PROTEIN BLOOD LEVEL; SCHOOL CHILD; SERUM OSMOLALITY;

ADOLESCENT; C-REACTIVE PROTEIN; CHILD; CHILD, PRESCHOOL; CYTOKINES; DIABETES MELLITUS, TYPE 1; DIABETIC KETOACIDOSIS; FEMALE; HUMANS; INTERLEUKIN-10; INTERLEUKIN-1BETA; INTERLEUKIN-2; INTERLEUKIN-6; INTERLEUKIN-8; LEUKOCYTE COUNT; MALE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84855175281     PISSN: 09188959     EISSN: 13484540     Source Type: Journal    
DOI: 10.1507/endocrj.EJ11-0024     Document Type: Article

References (37)

1. Levitsky L, Ekwo E, Goselink C, Solomon I, et al. (1991) Death from diabetes (DM) in hospitalized children (1970-1988). Pediatr Res 29: A195.
2. Hoffman WH, Steinhart CM, El Gammal T, Steele S, Cuadrado AR, Morse PK (1988) Cranial computed tomography in children and adolescents with diabetic ketoacidosis. Am J Neuroradiol 9: 733-739.
3. Durr JA, Hoffman WH, Sklar AH, El Gammal T, Steinhart CM (1992) Correlates of brain edema in uncontrolled insulin-dependent diabetes. Diabetes 41: 627-632.
4. Hoffman WH, Locksmith JP, Burton EM, Hobbs E, Passmore GG, Pearson-Shaver AL (1998) Interstitial pulmonary edema in children and adolescents with diabetic ketoacidosis. J Diabetes Complications 12: 314-320.
5. Glaser N (2006) New Perspectives on the pathogenesis of cerebral edema complicating diabetic ketoacidosis in children. Pediatr Endocrinol Rev 3(4): 379-386.
6. Hoffman WH, Burek CL, Waller JL, Fisher LE, Khichi M, Mellick LB (2003) Cytokine response to diabetic ketoacidosis and its treatment. Clin Immunol 108: 175-181.
7. Slifka MK, Whitton JL (2000) Clinical implications of dysregulated cytokine production. J Mol Med 78: 74-80.
8. Yeh FL, Lin WL, Shen HD (2000) Changes in circulating levels of anti-inflammatory cytokine interleukin 10 in burned patients. Burns 26: 454-459.
9. Erbagci AB, Tarakcioglu M, Coskun Y, Sivasli E, Sibel Namiduru E (2001) Mediators of inflammation in children with type I diabetes mellitus: cytokines in type I diabetic children. Clin Biochem 34(8):645-650.
10. Wedrychowicz A, Dziatkowiak H, Sztefko K, Wedrychowicz A (2004) Interleukin-6 (IL-6) and IGFIGFBP system in children and adolescents with type 1 diabetes mellitus. Exp Clin Endocrinol Diabetes 112(8): 435-439.
11. Wasmuth HE, Kunz D, Graf J, Stanzel S, Purucker EA, Koch A et al. (2004) Hyperglycaemia at admission to the intensive care unit is associated with elevated serum concentrations of interleukin-6 and reduced ex vivo secretion of tumor necrosis factor-a. Crit Care Med 32(5): 1109-1114.
12. Esposito K, Nappo F, Marfella R, Giugliano G, Giugliano F, Ciotola M et al. (2002) Inflammatory cytokine concentrations are acutely increased by hyperglycaemia in humans: role of oxidative stress. Circulation 106: 2067-2072.
13. Goebel MU, Mills PJ, Irwin MR, Ziegler MG (2000) Interleukin-6 and tumor necrosis factor-a production after acute psychological stress, exercise and infused isopraterenal: differential effects and pathway. Psychosom Med 62: 591-598.
14. Pickup JC, Chusney GD, Thomas SM, Burt D (2000) Plasma interleukin-6, tumour necrosis factor alpha and blood cytokine production in type 2 diabetes. Life Sci 67: 291-300.
15. Jain SK, Kannan K, Lim G, Matthews-Greer J, McVie R, Bocchini JA (2003) Elevated blood interleukin-6 levels in hyperketonemic type 1 diabetic patients and secretion by acetoacetate-treated cultured U937 monocytes. Diabetes Care 26: 2139-2143.
16. Stentz FB, Umpierrez GE, Cuervo R, Kitabchi AE (2004) Proinflammatory cytokines, markers of cardiovascular risks, oxidative stress and lipid peroxidation in patients with hyperglycaemic crisis. Diabetes 53: 2079-2086.
17. Cucullo L, Marchi N, Marroni M, Fazio V, Namura S, Janigro D (2003) Blood-brain barrier damage includes release of alpha2-macroglobulin. Mol Cell Proteomics 2(4): 234-241.
18. Roch A, Castanier M, Mardelle V, Trousse D, Marin V, Avaro JP et al. (2008) Effect of hypertonic saline pretreatment on ischemia-reperfusion lung injury in pig. J Heart Lung Transplant 27(9): 1023-1030.
19. Inoue K, Takano H, Sakurai M, Oda T, Tamura H, Yanagisawa R, Shimada A, Yoshikawa T (2006) Pulmonary exposure to diesel exhaust particles enhances coagulatory disturbance with endothelial damage and systemic inflammation related to lung inflammation. Exp Biol Med (Maywood) 231(10): 1626-1632.
20. Breithaupt-Faloppa AC, Vitoretti LB, Coelho FR, dos Santos Franco AL, Domingos HV, Sudo-Hayashi LS et al. (2009) Nitric oxide mediates lung vascular permeability and lymph-borne IL-6 after an intestinal ischemic insult. Shock 32(1): 55-61.
21. Sedgwick JB, Menon I, Gern JE, Busse WW (2002) Effects of inflammatory cytokines on the permeability of human lung microvascular endothelial cell monolayers and differential eosinophil transmigration. J Allergy Clin Immunol 110: 752-756.
22. Singh U, Devaraj S, Dasu MR, Ciobanu D, Reusch J, Jialal I (2006) C-reactive protein decreases interleukin-10 secretion in activated human monocyte-derived macrophages via inhibition of cyclic AMP production. Arterioscler Thromb Vasc Biol 26: 2469-2475.
23. Oshima T, Laroux FS, Coe LL, Morise Z, Kawachi S, Bauer P et al. (2001) Interferon-gamma and interleukin-10 reciprocally regulate endothelial junction integrity and barrier function. Microvasc Res 61(1): 130-143.
24. Matsumoto K (1997) Interleukin 10 inhibits vascular permeability factor release by peripheral blood mononuclear cells in patients with lipoid nephrosis. Nephron 75(2): 154-159.
25. Matsumoto K, Ohi H, Kanmatsuse K (1997) Interleukin 10 and interleukin 13 synergize to inhibit vascular permeability factor release by peripheral blood mononuclear cells from patients with lipoid nephrosis. Nephron 77(2): 212-218.
26. Mao M, Wang SN, Lv XJ, Wang Y, Xu JC (2010) Intravenous delivery of bone marrow-derived endothelial progenitor cells improves survival and attenuates lipopolysaccharide-induced lung injury in rats. Shock 34(2): 196-204.
27. Expert Committee on the Diagnosis and Classification of Diabetes Mellitus (2003) Follow-up report on the diagnosis of diabetes mellitus. Diabetes Care 26: 3160-3167.
28. ISPAD Consensus Guidelines 2000 for the management of Type 1 Diabetes Mellitus in children and adolescents. Ed.PGF Swift.Publ.Medforum, Zeist, Netherlands. p.63-64.
29. Klein M, Sathasivam A, Novoa Y, Rapaport R (2009) Recent consensus statements in pediatric endocrinology: a selective review. Endocrinol Metab Clin North Am 38(4): 811-825.
30. Bruun JM, Pederson SB, Richelsen B (2000) Interleukin-8 production in human adipose tissue. Inhibitory effect of anti-diabetic compounds, the thiazollidinedione ciglitazone and the biguanide metformin. Horm Metab Res 32: 537-541.
31. Hansen TK, Thiel S, Wouters PJ, Chrstiansen JS, Van den Berghe G (2003) Intensive insulin therapy exerts anti-inflammatory effects in critically ill patients and counteracts the adverse effect of low mannose-binding lectin levels. J Clin Endocrinol Metab 88: 1082-1088.
32. Dandona P, Aljada A, Mohanty P (2002) The anti-inflammatory and potential antiatherogenic effect of insulin: a new paradigm. Diabetologia 45: 924-930.
33. Suffredini AF, Fiantazzi G, Badolto R, Oppenheimer J, O'Grady N (1999) New insights into the biology of acute phase response. J Clin Immunol 19: 203-214.
34. Kitabchi AE, Stentz FB, Umpierrez GE (2004) Diabetic ketoacidosis induces in vivo activation of T-lymphocytes. Biochem Biophys Res Commun 315(2): 404-407.
35. Viardot A, Grey ST, Mackay F, Chishom D (2007) Potential antiiflammatory role of insulin via the preferential polarization of effector T cells toward a T Helper 2 Phenotype. Endocrinology 148 (1): 346-353.
36. Wall Malefy R, Abrams J, Bennett CG, de Vris JE (1991) Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes. J Exp Med 174: 1209-1220.
37. Pajkrt D, Camoglio L, Tiel-van Buul MC, de Bruin K, Cutler DL, Affrime MB et al. (1997) Attenuation of proinflammatory response by recombinant human IL-10 in human endotoxemia: effect of timing of recombinant human IL-10 administration. J Immunol 158(8): 3971-3977.