Transient gene silencing of galectin-3 suppresses pancreatic cancer cell migration and invasion through degradation of β-catenin

International Journal of Cancer

Volumn 129, Issue 12, 2011, Pages 2775-2786

  Kobayashi, Tsutomu ^a   Shimura, Tatsuo ^a,b   Yajima, Toshiki ^a   Kubo, Norio ^a   Araki, Kenichiro ^a   Tsutsumi, Soichi ^a   Suzuki, Hideki ^a   Kuwano, Hiroyuki ^a   Raz, Avraham ^c  

^a GUNMA UNIVERSITY   (Japan)

^b FUKUSHIMA UNIVERSITY   (Japan)

^c WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

catenin; Galectin 3; Invasion; MMP 2; Pancreatic cancer; Wnt

Indexed keywords

BETA CATENIN; BETA GALACTOSIDE; GALECTIN 3; GELATINASE A; GLYCOGEN SYNTHASE KINASE 3BETA; PROTEIN KINASE B; SMALL INTERFERING RNA; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA;

ANGIOGENESIS; ANTIANGIOGENIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL ADHESION; CELL DIFFERENTIATION; CELL INVASION; CELL MOTILITY; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; DRUG PROTEIN BINDING; DRUG TARGETING; GENE SILENCING; HUMAN; HUMAN CELL; METASTASIS; MIGRATION INHIBITION; PANCREAS CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS INHIBITION; SIGNAL DETECTION; CANCER INVASION; CELL MOTION; GENETICS; METABOLISM; PANCREAS TUMOR; PATHOLOGY; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

BETA CATENIN; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; GALECTIN 3; GENE SILENCING; GLYCOGEN SYNTHASE KINASE 3; HUMANS; MATRIX METALLOPROTEINASE 2; NEOPLASM INVASIVENESS; PANCREATIC NEOPLASMS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

EID: 84855170684     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.25946     Document Type: Article

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