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Volumn 22, Issue 1, 2012, Pages 666-678
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Synthesis, antitubercular evaluation and 3D-QSAR study of N-phenyl-3-(4-fluorophenyl)-4-substituted pyrazole derivatives
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Author keywords
3D QSAR; Antitubercular agents; CoMFA; CoMSIA; Mycobacterium tuberculosis; Pyrazole
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Indexed keywords
TUBERCULOSTATIC AGENT;
ANTIBACTERIAL ACTIVITY;
ARTICLE;
BIOLOGICAL ACTIVITY;
COMPARATIVE MOLECULAR FIELD ANALYSIS;
COMPARATIVE MOLECULAR SIMILARITY INDICES ANALYSIS;
CONTROLLED STUDY;
DRUG STRUCTURE;
DRUG SYNTHESIS;
HYDROGEN BOND;
HYDROPHOBICITY;
IN VITRO STUDY;
MYCOBACTERIUM TUBERCULOSIS;
NONHUMAN;
QUANTITATIVE STRUCTURE ACTIVITY RELATION;
STATIC ELECTRICITY;
ANTI-BACTERIAL AGENTS;
ANTITUBERCULAR AGENTS;
CHEMISTRY, PHARMACEUTICAL;
DRUG DESIGN;
HUMANS;
HYDROGEN BONDING;
HYDROPHOBIC AND HYDROPHILIC INTERACTIONS;
INHIBITORY CONCENTRATION 50;
KETONES;
MODELS, CHEMICAL;
MOLECULAR CONFORMATION;
MYCOBACTERIUM TUBERCULOSIS;
PYRAZOLES;
QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;
STATIC ELECTRICITY;
TEMPERATURE;
MYCOBACTERIUM TUBERCULOSIS;
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EID: 84655169278
PISSN: 0960894X
EISSN: 14643405
Source Type: Journal
DOI: 10.1016/j.bmcl.2011.10.059 Document Type: Article |
Times cited : (91)
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References (27)
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