Synthesis of novel substituted pyrazolyl-2-toluidinomethanethione and pyrazolyl-2-methoxyanilinomethanethione as potential antitubercular agents

Acta Poloniae Pharmaceutica - Drug Research

Volumn 64, Issue 2, 2007, Pages 139-146

  Ali, Mohamed Ashraf ^a   Yar, Mohammad Shahar ^a  

^a HAMDARD UNIVERSITY   (India)

Author keywords

Antimycobacterial; Pyrazolines

Indexed keywords

5 [2 CHLOROPHENYL] 3 (4 HYDROXY 3 METHYL) 4,5 DIHYDRO 1H 1 PYRAZOLYL 2 TOLUIDINOMETHANETHIONE; 5 [2 CHLOROPHENYL] 3 (4 HYDROXY 3 METHYLPHENYL) 4,5 DIHYDRO 1H 1 PYRAZOLYL 2 METHOXYANILINOMETHANETHIONE; 5 [2,6 DICHLOROPHENYL] 3 (4 HYDROXY 3 METHYL) 4,5 DIHYDRO 1H 1 PYRAZOLYL 2 TOLUIDINOMETHANETHIONE; 5 [2,6 DICHLOROPHENYL] 3 (4 HYDROXY 3 METHYLPHENYL) 4,5 DIHYDRO 1H 1 PYRAZOLYL 2 METHOXYANILINOMETHANETHIONE; 5 [3 NITROPHENYL] 3 (4 HYDROXY 3 METHYL) 4,5 DIHYDRO 1H 1 PYRAZOLYL 2 TOLUIDINOMETHANETHIONE; 5 [3 NITROPHENYL] 3 (4 HYDROXY 3 METHYLPHENYL) 4,5 DIHYDRO 1H 1 PYRAZOLYL 2 METHOXYANILINOMETHANETHIONE; 5 [3,4 DIMETHOXYPHENYL] 3 (4 HYDROXY 3 METHYL) 4,5 DIHYDRO 1H 1 PYRAZOLYL 2 TOLUIDINOMETHANETHIONE; 5 [3,4 DIMETHOXYPHENYL] 3 (4 HYDROXY 3 METHYLPHENYL) 4,5 DIHYDRO 1H 1 PYRAZOLYL 2 METHOXYANILINOMETHANETHIONE; 5 [3,4,5 TRIMETHOXYPHENYL] 3 (4 HYDROXY 3 METHYLPHENYL) 4,5 DIHYDRO 1H 1 PYRAZOLYL 2 METHOXYANILINOMETHANETHIONE; 5 [3,4.5 TRIMETHOXYPHENYL] 3 (4 HYDROXY 3 METHYL) 4,5 DIHYDRO 1H 1 PYRAZOLYL 2 TOLUIDINOMETHANETHIONE; 5 [4 CHLOROPHENYL] 3 (4 HYDROXY 3 METHYL) 4,5 DIHYDRO 1H 1 PYRAZOLYL 2 TOLUIDINOMETHANETHIONE; 5 [4 CHLOROPHENYL] 3 (4 HYDROXY 3 METHYLPHENYL) 4,5 DIHYDRO 1H 1 PYRAZOLYL 2 METHOXYANILINOMETHANETHIONE; 5 [4 FLUOROPHENYL] 3 (4 HYDROXY 3 METHYLPHENYL) 4,5 DIHYDRO 1H 1 PYRAZOLYL 2 METHOXYANILINOMETHANETHIONE; 5 [4 METHOXYPHENYL] 3 (4 HYDROXY 3 METHYL) 4,5 DIHYDRO 1H 1 PYRAZOLYL 2 TOLUIDINOMETHANETHIONE; 5 [4 METHOXYPHENYL] 3 (4 HYDROXY 3 METHYLPHENYL) 4,5 DIHYDRO 1H 1 PYRAZOLYL 2 METHOXYANILINOMETHANETHIONE; 5 [DIMETHYLAMINOPHENYL] 3 (4 HYDROXY 3 METHYL) 4,5 DIHYDRO 1H 1 PYRAZOLYL 2 TOLUIDINOMETHANETHIONE; 5 [FLUOROPHENYL] 3 (4 HYDROXY 3 METHYL) 4,5 DIHYDRO 1H 1 PYRAZOLYL 2 TOLUIDINOMETHANETHIONE; 5 FURYL 3 (4 HYDROXY 3 METHYL) 4,5 DIHYDRO 1H 1 PYRAZOLYL 2 TOLUIDINOMETHANETHIONE; 5 FURYL 3 (4 HYDROXY 3 METHYLPHENYL) 4,5 DIHYDRO 1H 1 PYRAZOLYL 2 METHOXYANILINOMETHANETHIONE; 5 PHENYL 3 (4 HYDROXY 3 METHYL) 4,5 DIHYDRO 1H 1 PYRAZOLYL 2 TOLUIDINOMETHANETHIONE; 5 PHENYL 3 (4 HYDROXY 3 METHYLPHENYL) 4,5 DIHYDRO 1H 1 PYRAZOLYL 2 METHOXYANILINOMETHANETHIONE; ANTIMYCOBACTERIAL AGENT; ISONIAZID; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG; PYRAZOLE DERIVATIVE;

ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG EFFICACY; DRUG STRUCTURE; DRUG SYNTHESIS; IN VITRO STUDY; INFRARED SPECTROMETRY; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STRUCTURE ACTIVITY RELATION; THIN LAYER CHROMATOGRAPHY; VERO CELL; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; GENETICS; IC 50; IMMUNOLOGY; METHODOLOGY; MICROBIOLOGICAL EXAMINATION; SYNTHESIS;

ANTITUBERCULAR AGENTS; INHIBITORY CONCENTRATION 50; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; MYCOBACTERIUM TUBERCULOSIS; PYRAZOLES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 35148893201     PISSN: 00016837     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)