The adenosine derivative 2′,3′,5′-tri-O-acetyl-N6-(3- hydroxylaniline) adenosine activates AMPK and regulates lipid metabolism in vitro and in vivo

Life Sciences

Volumn 90, Issue 1-2, 2012, Pages 1-7

  Guo, Peng ^a   Lian, Ze Qin ^b   Sheng, Ling Hui ^c   Wu, Chong Ming ^d   Gao, Jian ^b   Li, Jin ^b   Wang, Yao ^b   Guo, Yan Shen ^b   Zhu, Hai Bo ^b  

^a INSTITUTE OF MEDICINAL PLANT DEVELOPMENT   (China)

^b INSTITUTE OF MATERIA MEDICA   (China)

^c NATIONAL INSTITUTE OF METROLOGY   (China)

^d TSINGHUA UNIVERSITY   (China)

Author keywords

Adenosine derivative; AMP activated protein kinase (AMPK); Hyperlipidemia; WS010117

Indexed keywords

2',3',5' TRI O ACETYL N6 (3 HYDROXYLANILINE) ADENOSINE; ACETIC ACID; ADENOSINE DERIVATIVE; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE; CARBON 14; CHOLESTEROL; FATTY ACID; HIGH DENSITY LIPOPROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; HYDROXYMETHYLGLUTARYLCOENZYME A REDUCTASE KINASE GAMMA 1; LOW DENSITY LIPOPROTEIN; PALMITIC ACID; PHOSPHOTRANSFERASE INHIBITOR; PROTEIN KINASE LKB1; SMALL INTERFERING RNA; STO 609; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; WS 010117;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CHEMICAL ANALYSIS; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; FATTY ACID BLOOD LEVEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIPID DIET; LIPID METABOLISM; LIPID OXIDATION; LIPID STORAGE; LIPOGENESIS; MALE; MOLECULAR DOCKING; NONHUMAN; PROTEIN BLOOD LEVEL; WESTERN BLOTTING;

ADENOSINE; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; CELLS, CULTURED; CRICETINAE; DIETARY FATS; ENZYME ACTIVATION; HELA CELLS; HEP G2 CELLS; HUMANS; LIPID METABOLISM; MALE; MESOCRICETUS; PYRAZOLES; PYRIMIDINES;

CRICETINAE;

EID: 84655164329     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2011.09.001     Document Type: Article

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