Antagonism of NMDA receptors by butanesulfonyl-homospermine guanidine and neuroprotective effects in in vitro and in vivo

Neuroscience Letters

Volumn 506, Issue 2, 2012, Pages 251-255

  Masuko, Takashi ^a   Suzuki, Toyofumi ^a   Miyake, Muneharu ^a   Kusama Eguchi, Kuniko ^a   Kizawa, Yasuo ^a   Tomono, Kazuo ^a   Kashiwagi, Keiko ^b   Igarashi, Kazuei ^c   Kusama, Tadashi ^a  

^a NIHON UNIVERSITY   (Japan)

^b CHIBA INSTITUTE OF SCIENCE   (Japan)

^c CHIBA UNIVERSITY   (Japan)

Author keywords

N< rk italic> methyl d aspartate receptor; Ischemia; Neuroprotection; Polyamine derivative; Xenopus oocytes

Indexed keywords

ALANINE; BUTANESULFONYL HOMOSPERMINE GUANIDINE; GLUTAMATE RECEPTOR 1; GUANIDINE DERIVATIVE; MEMANTINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2C; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2D; THREONINE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN INFARCTION; BRAIN ISCHEMIA; CONTROLLED STUDY; DRUG INHIBITION; FEMALE; GENE MUTATION; IC 50; IN VITRO STUDY; IN VIVO STUDY; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NEUROPROTECTION; NONHUMAN; OOCYTE; PRIORITY JOURNAL; VOLTAGE CLAMP; XENOPUS LAEVIS;

ANIMALS; BRAIN ISCHEMIA; CELL LINE, TUMOR; CELL SURVIVAL; EXCITATORY AMINO ACID ANTAGONISTS; FEMALE; GUANIDINE; HUMANS; MEMANTINE; MICE; NEUROPROTECTIVE AGENTS; PATCH-CLAMP TECHNIQUES; POLYAMINES; RECEPTORS, N-METHYL-D-ASPARTATE; SPERMINE; XENOPUS LAEVIS;

EID: 84655163975     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2011.11.017     Document Type: Article

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