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Volumn 506, Issue 2, 2012, Pages 271-276

Overexpression of TDP-43 causes partially p53-dependent G2/M arrest and p53-independent cell death in HeLa cells

Author keywords

ALS; Cell cycle; FTLD U; Non neuron autonomous toxicity; P53; TDP 43

Indexed keywords

PROTEIN P53; TAR DNA BINDING PROTEIN;

EID: 84655163935     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2011.11.021     Document Type: Article
Times cited : (12)

References (23)
  • 2
    • 33749056809 scopus 로고    scopus 로고
    • ALS: a disease of motor neurons and their nonneuronal neighbors
    • Boillée S., Vande Velde C., Cleveland D.W. ALS: a disease of motor neurons and their nonneuronal neighbors. Neuron 2006, 52:39-59.
    • (2006) Neuron , vol.52 , pp. 39-59
    • Boillée, S.1    Vande Velde, C.2    Cleveland, D.W.3
  • 5
    • 77949910265 scopus 로고    scopus 로고
    • Review: transactive response DNA-binding protein 43 (TDP-43): mechanisms of neurodegeneration
    • Gendron T.F., Josephs K.A., Petrucelli L. Review: transactive response DNA-binding protein 43 (TDP-43): mechanisms of neurodegeneration. Neuropathol. Appl. Neurobiol. 2010, 36:97-112.
    • (2010) Neuropathol. Appl. Neurobiol. , vol.36 , pp. 97-112
    • Gendron, T.F.1    Josephs, K.A.2    Petrucelli, L.3
  • 6
    • 0026699985 scopus 로고
    • Protease inhibitors generate cytotoxic fragments from Alzheimer amyloid protein precursor in cDNA-transfected glioma cells
    • Hayashi Y., Kashiwagi K., Yoshikawa K. Protease inhibitors generate cytotoxic fragments from Alzheimer amyloid protein precursor in cDNA-transfected glioma cells. Biochem. Biophys. Res. Commun. 1992, 187:1249-1255.
    • (1992) Biochem. Biophys. Res. Commun. , vol.187 , pp. 1249-1255
    • Hayashi, Y.1    Kashiwagi, K.2    Yoshikawa, K.3
  • 7
    • 74049164709 scopus 로고    scopus 로고
    • Non-cell autonomous toxicity in neurodegenerative disorders: ALS and beyond
    • Ilieva H., Polymenidou M., Cleveland D.W. Non-cell autonomous toxicity in neurodegenerative disorders: ALS and beyond. J. Cell Biol. 2009, 187:761-772.
    • (2009) J. Cell Biol. , vol.187 , pp. 761-772
    • Ilieva, H.1    Polymenidou, M.2    Cleveland, D.W.3
  • 9
    • 77953890823 scopus 로고    scopus 로고
    • TDP-43, FUS/TLS: emerging roles in RNA processing and neurodegeneration
    • Lagier-Tourenne C., Polymenidou M., Cleveland D.W. TDP-43, FUS/TLS: emerging roles in RNA processing and neurodegeneration. Hum. Mol. Genet. 2010, 19(R1):R46-R64.
    • (2010) Hum. Mol. Genet. , vol.19 , Issue.R1
    • Lagier-Tourenne, C.1    Polymenidou, M.2    Cleveland, D.W.3
  • 10
    • 34447099071 scopus 로고    scopus 로고
    • Gene expression analysis of frontotemporal lobar degeneration of the motor neuron disease type with ubiquitinated inclusions
    • Mishra M., Paunesku T., Woloschak G.E., Siddique T., Zhu L.J., Lin S., Greco K., Bigio E.H. Gene expression analysis of frontotemporal lobar degeneration of the motor neuron disease type with ubiquitinated inclusions. Acta Neuropathol. 2007, 114:81-94.
    • (2007) Acta Neuropathol. , vol.114 , pp. 81-94
    • Mishra, M.1    Paunesku, T.2    Woloschak, G.E.3    Siddique, T.4    Zhu, L.J.5    Lin, S.6    Greco, K.7    Bigio, E.H.8
  • 12
    • 47949096734 scopus 로고    scopus 로고
    • Sporadic amyotrophic lateral sclerosis: two pathological patterns shown by analysis of distribution of TDP-43-immunoreactive neuronal and glial cytoplasmic inclusions
    • Nishihira Y., Tan C.F., Onodera O., Toyoshima Y., Yamada M., Morita T., Nishizawa M., Kakita A., Takahashi H. Sporadic amyotrophic lateral sclerosis: two pathological patterns shown by analysis of distribution of TDP-43-immunoreactive neuronal and glial cytoplasmic inclusions. Acta Neuropathol. 2008, 116:169-182.
    • (2008) Acta Neuropathol. , vol.116 , pp. 169-182
    • Nishihira, Y.1    Tan, C.F.2    Onodera, O.3    Toyoshima, Y.4    Yamada, M.5    Morita, T.6    Nishizawa, M.7    Kakita, A.8    Takahashi, H.9
  • 13
    • 77950665407 scopus 로고    scopus 로고
    • Frontotemporal lobar degeneration epidemiology, pathophysiology, diagnosis and management
    • Rabinovici G.D., Miller B.L. Frontotemporal lobar degeneration epidemiology, pathophysiology, diagnosis and management. CNS Drugs 2010, 24:375-398.
    • (2010) CNS Drugs , vol.24 , pp. 375-398
    • Rabinovici, G.D.1    Miller, B.L.2
  • 14
    • 60849093466 scopus 로고    scopus 로고
    • Current hypotheses for the underlying biology of amyotrophic lateral sclerosis
    • Rothstein J.D. Current hypotheses for the underlying biology of amyotrophic lateral sclerosis. Ann. Neurol. 2009, 65(Suppl. 1):S3-S9.
    • (2009) Ann. Neurol. , vol.65 , Issue.SUPPL. 1
    • Rothstein, J.D.1
  • 15
    • 77954887500 scopus 로고    scopus 로고
    • Suppression of the novel ER protein Maxer by mutant ataxin-1 in Bergman glia contributes to non-cell-autonomous toxicity
    • Shiwaku H., Yoshimura N., Tamura T., Sone M., Ogishima S., Watase K., Tagawa K., Okazawa H. Suppression of the novel ER protein Maxer by mutant ataxin-1 in Bergman glia contributes to non-cell-autonomous toxicity. EMBO J. 2010, 29:2446-2460.
    • (2010) EMBO J. , vol.29 , pp. 2446-2460
    • Shiwaku, H.1    Yoshimura, N.2    Tamura, T.3    Sone, M.4    Ogishima, S.5    Watase, K.6    Tagawa, K.7    Okazawa, H.8
  • 16
    • 0032513326 scopus 로고    scopus 로고
    • A novel and rapid method for culturing pure rat spinal cord astrocytes on untreated glass
    • Silva G.A., Feeney C., Mills L.R., Theriault E. A novel and rapid method for culturing pure rat spinal cord astrocytes on untreated glass. J. Neurosci. Methods 1998, 80:75-79.
    • (1998) J. Neurosci. Methods , vol.80 , pp. 75-79
    • Silva, G.A.1    Feeney, C.2    Mills, L.R.3    Theriault, E.4
  • 18
    • 79953855830 scopus 로고    scopus 로고
    • TDP-43-induced death is associated with altered regulation of BIM and BCL-XL and attenuated by caspase-mediated TDP-43 cleavage
    • Suzuki H., Lee K., Matsuoka M. TDP-43-induced death is associated with altered regulation of BIM and BCL-XL and attenuated by caspase-mediated TDP-43 cleavage. J. Biol. Chem. 2011, 286:13171-13183.
    • (2011) J. Biol. Chem. , vol.286 , pp. 13171-13183
    • Suzuki, H.1    Lee, K.2    Matsuoka, M.3
  • 19
    • 84855889048 scopus 로고    scopus 로고
    • TDP-43 toxicity is mediated by the unfolded protein response-unrelated induction of C/EBP homologous protein expression
    • in press.
    • H. Suzuki, M. Matsuoka, TDP-43 toxicity is mediated by the unfolded protein response-unrelated induction of C/EBP homologous protein expression, J. Neurosci. Res., in press.
    • J. Neurosci. Res.
    • Suzuki, H.1    Matsuoka, M.2
  • 21
    • 0035110714 scopus 로고    scopus 로고
    • Involvement of the Oct-1 regulatory element of the gadd45 promoter in the p53-independent response to ultraviolet irradiation
    • Takahashi S., Saito S., Ohtani N., Sakai T. Involvement of the Oct-1 regulatory element of the gadd45 promoter in the p53-independent response to ultraviolet irradiation. Cancer Res. 2001, 61:1187-1195.
    • (2001) Cancer Res. , vol.61 , pp. 1187-1195
    • Takahashi, S.1    Saito, S.2    Ohtani, N.3    Sakai, T.4
  • 22
    • 0035810054 scopus 로고    scopus 로고
    • Regulation of the G2/M transition by p53
    • Taylor W.R., Stark G.R. Regulation of the G2/M transition by p53. Oncogene 2001, 20:1803-1815.
    • (2001) Oncogene , vol.20 , pp. 1803-1815
    • Taylor, W.R.1    Stark, G.R.2
  • 23
    • 80054707323 scopus 로고    scopus 로고
    • Genetic strategies to study TDP-43 in rodents and to develop preclinical therapeutics for amyotrophic lateral sclerosis
    • Wang D.B., Gitcho M.A., Kraemer B.C., Klein R.L. Genetic strategies to study TDP-43 in rodents and to develop preclinical therapeutics for amyotrophic lateral sclerosis. Eur. J. Neurosci. 2011, 34:1179-1188.
    • (2011) Eur. J. Neurosci. , vol.34 , pp. 1179-1188
    • Wang, D.B.1    Gitcho, M.A.2    Kraemer, B.C.3    Klein, R.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.