Inhibition of endoplasmic reticulum stress by intermedin 1-53 protects against myocardial injury through a PI3 kinase-Akt signaling pathway

Journal of Molecular Medicine

Volumn 89, Issue 12, 2011, Pages 1195-1205

  Teng, Xu ^a,c,d   Song, Junqiu ^b   Zhang, Gaigai ^b   Cai, Yan ^a   Yuan, Fang ^c,d   Du, Jie ^a   Tang, Chaoshu ^a,b   Qi, Yongfen ^a,b  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b PEKING UNIVERSITY   (China)

^c HEBEI MEDICAL UNIVERSITY   (China)

^d Hebei Key Laboratory of Laboratory Animal Science   (China)

Author keywords

Apoptosis; Endoplasmic reticulum stress; Intermedin; Ischemia reperfusion injury; Myocardium

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; ACTIVATING TRANSCRIPTION FACTOR 4; ACTIVATING TRANSCRIPTION FACTOR 6; CASPASE 12; CCAAT ENHANCER BINDING PROTEIN; DITHIOTHREITOL; GLUCOSE REGULATED PROTEIN 78; INTERMEDIN 1-53; INTERMEDIN DERIVATIVE; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TUNICAMYCIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; HEART MUSCLE INJURY; HEART MUSCLE ISCHEMIA; HEART PROTECTION; IN VITRO STUDY; IN VIVO STUDY; INHIBITION KINETICS; MALE; NONHUMAN; RAT; REPERFUSION INJURY; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; CARDIOTONIC AGENTS; CASPASE 12; DISEASE MODELS, ANIMAL; ENDOPLASMIC RETICULUM STRESS; HEAT-SHOCK PROTEINS; HSP70 HEAT-SHOCK PROTEINS; L-LACTATE DEHYDROGENASE; MALE; MALONDIALDEHYDE; MEMBRANE PROTEINS; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; PEPTIDE HORMONES; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; TRANSCRIPTION FACTOR CHOP;

EID: 84655163428     PISSN: 09462716     EISSN: 14321440     Source Type: Journal    
DOI: 10.1007/s00109-011-0808-5     Document Type: Article

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