Effect of apoptotic and proliferative indices, P-glycoprotein and survivin expression on prognosis in laryngeal squamous cell carcinoma

Medical Oncology

Volumn 28, Issue SUPPL. 1, 2011, Pages

  Li, Da Wei ^a   Gao, Shang ^a   Shen, Bin ^a   Dong, Pin ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Apoptosis; Cell proliferation; Laryngeal squamous cell carcinoma; P glycoprotein; Prognosis; Survivin

Indexed keywords

GLYCOPROTEIN P; KI 67 ANTIGEN; SURVIVIN;

ADULT; AGED; APOPTOSIS; ARTICLE; CANCER GROWTH; CELL PROLIFERATION; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LARYNX CARCINOMA; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; NICK END LABELING; OVERALL SURVIVAL; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; SQUAMOUS CELL CARCINOMA; UPREGULATION;

EID: 84655163235     PISSN: 13570560     EISSN: 1559131X     Source Type: Journal    
DOI: 10.1007/s12032-010-9686-x     Document Type: Article

References (30)

1. EA Chu YJ Kim 2008 Laryngeal cancer: diagnosis and preoperative work-up Otolaryngol Clin North Am 41 673 695 (Pubitemid 351836078)
2. MR Hussein K Cullen 2001 Molecular biomarkers in HNSCC: prognostic and therapeutic implications Expert Rev Anticancer Ther 1 116 124 (Pubitemid 34679401)
3. SI Pai WH Westra 2009 Molecular pathology of head and neck cancer: implications for diagnosis, prognosis, and treatment Annu Rev Pathol 4 49 70
4. DR Hipfner SM Cohen 2004 Connecting proliferation and apoptosis in development and disease Nat Rev Mol Cell Biol 5 805 815 (Pubitemid 39336274)
5. P Giménez-Bonafé A Tortosa R Pérez-Tomás 2009 Overcoming drug resistance by enhancing apoptosis of tumor cells Curr Cancer Drug Targets 9 3 320 340
6. M Gryczyński J Kobos H Niewiadomska W Pietruszewska 2000 Assessment of cell proliferation antigen Ki-67, protein p53 related to apoptosis and angiogenesis in laryngeal cancer Otolaryngol Pol 54 Suppl 31 191 195
7. H Teppo Y Soini J Melkko P Koivunen OP Alho 2003 Prognostic factors in laryngeal carcinoma: the role of apoptosis, p53, proliferation (Ki-67) and angiogenesis APMIS 111 451 457 (Pubitemid 36735002)
8. H Itamochi 2002 Low proliferation activity may be associated with chemoresistance in clear cell carcinoma of the ovary Obstet Gynecol 100 281 287 (Pubitemid 34874791)
9. T Licht 1992 Expression of the proliferation-associated Ki-67 antigen of transferrin receptors and of DNA polymerase alpha in human tumour lines: implications for in vitro chemoresistance J Cancer Res Clin Oncol 118 2 116 122
10. T Mizutani 2008 Genuine functions of P-glycoprotein (ABCB1) Curr Drug Metab 9 167 174 (Pubitemid 351461005)
11. L Li AC Jiang P Dong Y Wan ZW Yu 2007 The characteristics of Hep-2 cell with multiple drug resistance induced by Taxol Otolaryngol Head Neck Surg 137 659 664 (Pubitemid 47445893)
12. MJ Smyth E Krasovskis VR Sutton RW Johnstone 1998 The drug efflux protein, P-glycoprotein, additionally protects drug-resistant tumor cells from multiple forms of caspase-dependent apoptosis Proc Natl Acad Sci U S A 95 7024 7029
13. K Takanishi M Miyazaki M Ohtsuka N Nakajima 1997 Inverse relationship between P-glycoprotein expression and its proliferative activity in hepatocellular carcinoma Oncology 54 231 237 (Pubitemid 27160591)
14. L Li 2009 MDR1/P-gp and VEGF synergistically enhance the invasion of Hep-2 cells with multidrug resistance induced by taxol Ann Surg Oncol 16 1421 1428
15. B Wang 2008 Immunohistochemical expression and clinical significance of P-glycoprotein in previously untreated extranodal NK/T-cell lymphoma, nasal type Am J Hematol 83 10 795 799
16. MR Raspollini G Amunni A Villanucci V Boddi GL Taddei 2005 Increased cyclooxygenase-2 (COX-2) and P-glycoprotein-170 (MDR1) expression is associated with chemotherapy resistance and poor prognosis. Analysis in ovarian carcinoma patients with low and high survival Int J Gynecol Cancer 15 255 260 (Pubitemid 40396961)
17. H Yamamoto CY Ngan M Monden 2008 Cancer cells survive with survivin Cancer Sci 99 1709 1714
18. H Sharma S Sen L Lo Muzio A Mariggiò N Singh 2005 Antisense-mediated downregulation of anti-apoptotic proteins induces apoptosis and sensitizes head and neck squamous cell carcinoma cells to chemotherapy Cancer Biol Ther 4 7 720 727 (Pubitemid 41351170)
19. S Mehrotra 2010 IAP regulation of metastasis Cancer Cell 17 53 64
20. H Zhao 2008 Prognostic significance of survivin and CD44v6 in laryngeal cancer surgical margins J Cancer Res Clin Oncol 134 1051 1058
21. G Marioni 2006 Expression of the apoptosis inhibitor protein survivin in primary laryngeal carcinoma and cervical lymph node metastasis Anticancer Res 26 3813 3817 (Pubitemid 44701464)
22. Z Shi 2007 Overexpression of survivin and XIAP in MDR cancer cells unrelated to P-glycoprotein Oncol Rep 17 969 976
23. F Liu 2010 Survivin transcription is associated with P-glycoprotein/MDR1 overexpression in the multidrug resistance of MCF-7 breast cancer cells Oncol Rep 23 1469 1475
24. IO Ng CL Liu ST Fan M Ng 2000 Expression of P-glycoprotein in hepatocellular carcinoma. A determinant of chemotherapy response Am J Clin Pathol 113 355 363 (Pubitemid 30217382)
25. FQ Alenzi 2004 Links between apoptosis, proliferation and the cell cycle Br J Biomed Sci 61 99 102 (Pubitemid 38879538)
26. P Hirvikoski 1999 Enhanced apoptosis correlates with poor survival in patients with laryngeal cancer but not with cell proliferation, bcl-2 or p53 expression Eur J Cancer 35 2 231 237 (Pubitemid 29136773)
27. L Seymour WR Bezwoda RD Dansey 1995 P-glycoprotein immunostaining correlates with ER and with high Ki67 expression but fails to predict anthracycline resistance in patients with advanced breast cancer Breast Cancer Res Treat 36 61 69
28. O Sagol 2005 The effect of apoptotic activity, survivin, Ki-67, and P-glycoprotein expression on prognosis in pancreatic carcinoma Pancreas 30 4 343 348 (Pubitemid 40586813)
29. CI Bang SY Paik DI Sun YH Joo MS Kim 2008 Cell growth inhibition and down-regulation of survivin by silibinin in a laryngeal squamous cell carcinoma cell line Ann Otol Rhinol Laryngol 117 10 781 785
30. XM Chen 2008 Suppression of survivin expression by short hairpin RNA induces apoptosis in human laryngeal carcinoma cells ORL J Otorhinolaryngol Relat Spec 70 3 168 175