-
1
-
-
0025741072
-
Magnetic resonance imaging in monitoring the treatment of multiple sclerosis: Concerted action guidelines
-
Miller, D. H. et al. Magnetic resonance imaging in monitoring the treatment of multiple sclerosis: Concerted action guidelines. J. Neurol. Neurosurg. Psychiatry 54, 683-688 (1991).
-
(1991)
J. Neurol. Neurosurg. Psychiatry
, vol.54
, pp. 683-688
-
-
Miller, D.H.1
-
2
-
-
9044245703
-
Guidelines for the use of magnetic resonance techniques in monitoring the treatment of multiple sclerosis
-
DOI 10.1002/ana.410390104
-
Miller, D. H. et al. Guidelines for the use of magnetic resonance techniques in monitoring the treatment of multiple sclerosis. US National MS Society Task Force. Ann. Neurol. 39, 6-16 (1996). (Pubitemid 26052212)
-
(1996)
Annals of Neurology
, vol.39
, Issue.1
, pp. 6-16
-
-
Miller, D.H.1
Albert, P.S.2
Barkhof, F.3
Francis, G.4
Frank, J.A.5
Hodgkinson, S.6
Lublin, F.D.7
Paty, D.W.8
Reingold, S.C.9
Simon, J.10
-
3
-
-
0037413467
-
A controlled trial of natalizumab for relapsing multiple sclerosis
-
DOI 10.1056/NEJMoa020696
-
Miller, D. H. et al. A controlled trial of natalizumab for relapsing multiple sclerosis. N. Engl. J. Med. 348, 15-23 (2003). (Pubitemid 36026342)
-
(2003)
New England Journal of Medicine
, vol.348
, Issue.1
, pp. 15-23
-
-
Miller, D.H.1
Khan, O.A.2
Sheremata, W.A.3
Blumhardt, L.D.4
Rice, G.P.A.5
Libonati, M.A.6
Willmer-Hulme, A.J.7
Dalton, C.M.8
Miszkiel, K.A.9
O'Connor, P.W.10
-
4
-
-
33645799680
-
A phase II study of the safety and efficacy of teriflunomide in multiple sclerosis with relapses
-
DOI 10.1212/01.wnl.0000203121.04509.31, PII 0000611420060328000022
-
O'Connor, P. W. et al. A Phase II study of the safety and efficacy of teriflunomide in multiple sclerosis with relapses. Neurology 66, 894-900 (2006). (Pubitemid 43739766)
-
(2006)
Neurology
, vol.66
, Issue.6
, pp. 894-900
-
-
O'Connor, P.W.1
Li, D.2
Freedman, M.S.3
Bar-Or, A.4
Rice, G.P.A.5
Confavreux, C.6
Paty, D.W.7
Stewart, J.A.8
Scheyer, R.9
-
5
-
-
77955799815
-
Oral fingolimod (FTY720) for relapsing multiple sclerosis
-
DOI 10.1056/NEJMoa052643
-
Kappos, L. et al. Oral fingolimod (FTY720) for relapsing multiple sclerosis. N. Engl. J. Med. 355, 1124-1140 (2006). (Pubitemid 44394919)
-
(2006)
New England Journal of Medicine
, vol.355
, Issue.11
, pp. 1124-1140
-
-
Kappos, L.1
Antel, J.2
Comi, G.3
Montalban, X.4
O'Connor, P.5
Polman, C.H.6
Haas, T.7
Korn, A.A.8
Karlsson, G.9
Radue, E.W.10
-
6
-
-
54149116366
-
Efficacy and safety of oral fumarate in patients with relapsing-remitting multiple sclerosis: A multicentre, randomised, double-blind, placebo-controlled phase IIb study
-
Kappos, L. et al. Efficacy and safety of oral fumarate in patients with relapsing-remitting multiple sclerosis: A multicentre, randomised, double-blind, placebo-controlled phase IIb study. Lancet 372, 1463-1472 (2008).
-
(2008)
Lancet
, vol.372
, pp. 1463-1472
-
-
Kappos, L.1
-
7
-
-
77949301468
-
Daclizumab in active relapsing multiple sclerosis (CHOICE study): A phase 2, randomised, double-blind, placebo-controlled, add-on trial with interferon beta
-
Wynn, D. et al. Daclizumab in active relapsing multiple sclerosis (CHOICE study): A phase 2, randomised, double-blind, placebo-controlled, add-on trial with interferon beta. Lancet Neurol. 9, 381-390 (2010).
-
(2010)
Lancet Neurol.
, vol.9
, pp. 381-390
-
-
Wynn, D.1
-
8
-
-
15244353263
-
Treatment with laquinimod reduces development of active MRI lesions in relapsing MS
-
Polman, C. H. et al. Treatment with laquinimod reduces development of active MRI lesions in relapsing MS. Neurology 64, 987-991 (2005).
-
(2005)
Neurology
, vol.64
, pp. 987-991
-
-
Polman, C.H.1
-
9
-
-
39049142995
-
B-cell depletion with rituximab in relapsing-remitting multiple sclerosis
-
DOI 10.1056/NEJMoa0706383
-
Hauser, S. L. et al. B-cell depletion with rituximab in relapsing-remitting multiple sclerosis. N. Engl. J. Med. 358, 676-688 (2008). (Pubitemid 351240747)
-
(2008)
New England Journal of Medicine
, vol.358
, Issue.7
, pp. 676-688
-
-
Hauser, S.L.1
Waubant, E.2
Arnold, D.L.3
Vollmer, T.4
Antel, J.5
Fox, R.J.6
Bar-Or, A.7
Panzara, M.8
Sarkar, N.9
Agarwal, S.10
Langer-Gould, A.11
Smith, C.H.12
-
10
-
-
0029751983
-
Increased MRI activity and immune activation in two multiple sclerosis patients treated with the monoclonal anti-tumor necrosis factor antibody cA2
-
van Oosten, B. W. et al. Increased MRI activity and immune activation in two multiple sclerosis patients treated with the monoclonal anti-tumor necrosis factor antibody cA2. Neurology 47, 1531-1534 (1996). (Pubitemid 26422549)
-
(1996)
Neurology
, vol.47
, Issue.6
, pp. 1531-1534
-
-
Van Oosten, B.W.1
Barkhof, F.2
Truyen, L.3
Boringa, J.B.4
Bertelsmann, F.W.5
Von Blomberg, B.M.E.6
Woody, J.N.7
Hartung, H.-P.8
Polman, C.H.9
-
11
-
-
0033546665
-
TNF neutralization in MS: Results of a randomized, placebo-controlled multicenter study. The Lenercept Multiple Sclerosis Study Group and The University of British Columbia MS/MRI Analysis Group
-
[No authors listed]
-
[No authors listed] TNF neutralization in MS: Results of a randomized, placebo-controlled multicenter study. The Lenercept Multiple Sclerosis Study Group and The University of British Columbia MS/MRI Analysis Group. Neurology 53, 457-465 (1999).
-
(1999)
Neurology
, vol.53
, pp. 457-465
-
-
-
12
-
-
0031458695
-
Ibuprofen does not suppress active multiple sclerosis lesions on gadolinium-enhanced MR images [1]
-
Barkhof, F., van Waesberghe, J. H., Uitdehaag, B. M. & Polman, C. H. Ibuprofen does not suppress active multiple sclerosis lesions on gadolinium-enhanced MR images. Ann. Neurol. 42, 982 (1997). (Pubitemid 28008431)
-
(1997)
Annals of Neurology
, vol.42
, Issue.6
, pp. 982
-
-
Barkhof, F.1
Van Waesberghe, J.-H.T.M.2
Uitdehaag, B.M.J.3
Polman, C.H.4
-
13
-
-
0042624771
-
Oral interferon beta-1a in relapsing-remitting multiple sclerosis: A double-blind randomized study
-
Polman, C. H. et al. Oral interferon beta-1a in relapsing-remitting multiple sclerosis: A double-blind randomized study. Mult. Scler. 9, 342-348 (2003).
-
(2003)
Mult. Scler.
, vol.9
, pp. 342-348
-
-
Polman, C.H.1
-
14
-
-
33847783332
-
The effect of oral temsirolimus on new magnetic resonance imaging scan lesions, brain atrophy, and the number of relapses in multiple sclerosis: Results from a randomised, controlled trial
-
Kappos, L., Barkhof, F. & Desmet, A. The effect of oral temsirolimus on new magnetic resonance imaging scan lesions, brain atrophy, and the number of relapses in multiple sclerosis: Results from a randomised, controlled trial. J. Neurol. 252 (Suppl. 2), 46 (2005).
-
(2005)
J. Neurol.
, vol.252
, Issue.SUPPL. 2
, pp. 46
-
-
Kappos, L.1
Barkhof, F.2
Desmet, A.3
-
15
-
-
48849087125
-
Ustekinumab MS Investigators. Repeated subcutaneous injections of IL12/23 p40 neutralising antibody, ustekinumab, in patients with relapsing-remitting multiple sclerosis: A phase II, double-blind, placebo-controlled, randomised, dose-ranging study
-
Segal, B. M. et al. Ustekinumab MS Investigators. Repeated subcutaneous injections of IL12/23 p40 neutralising antibody, ustekinumab, in patients with relapsing-remitting multiple sclerosis: A phase II, double-blind, placebo-controlled, randomised, dose-ranging study. Lancet Neurol. 7, 796-804 (2008).
-
(2008)
Lancet Neurol.
, vol.7
, pp. 796-804
-
-
Segal, B.M.1
-
16
-
-
32544449771
-
Effects of oral glatiramer acetate on clinical and MRI-monitored disease activity in patients with relapsing multiple sclerosis: A multicentre, double-blind, randomised, placebo-controlled study
-
DOI 10.1016/S1474-4422(06)70327-1, PII S1474442206703271
-
Filippi, M., Wolinsky, J. S., Comi, G. & CORAL Study Group. Effects of oral glatiramer acetate on clinical and MRI-monitored disease activity in patients with relapsing multiple sclerosis: A multicentre, double-blind, randomised, placebo-controlled study. Lancet Neurol. 5, 213-220 (2006). (Pubitemid 43238344)
-
(2006)
Lancet Neurology
, vol.5
, Issue.3
, pp. 213-220
-
-
Filippi, M.1
Wolinsky, J.S.2
Comi, G.3
-
17
-
-
22144491152
-
MRI results from the European Study on Intravenous Immunoglobulin in Secondary Progressive Multiple Sclerosis (ESIMS)
-
DOI 10.1191/1352458505ms1196oa
-
Fazekas, F. et al. MRI results from the European Study on Intravenous Immunoglobulin in Secondary Progressive Multiple Sclerosis (ESIMS). Mult. Scler. 11, 433-440 (2005). (Pubitemid 40984238)
-
(2005)
Multiple Sclerosis
, vol.11
, Issue.4
, pp. 433-440
-
-
Fazekas, F.1
Sorensen, P.S.2
Fillipi, M.3
Ropele, S.4
Lin, X.5
Koelmel, H.W.6
Fernandez, O.7
Pozzilli, C.8
O'Connor, P.9
Maas Enriquez, M.10
Hommes, O.R.11
Achiron, A.12
Hartung, H.P.13
Kappos, L.14
Kazatchkine, M.15
Noseworthy, J.16
Neiss, A.17
Kachel, R.18
Benecke, R.19
Hauenstein, K.20
Stark, E.21
Klein, S.22
Zierz, S.23
Schopp, G.24
Lowitzsch, K.25
Breer, H.26
Petereit, H.F.27
Impekoven, P.28
Japp, G.29
Zanella, F.30
Merkelbach, S.31
Reiche, W.32
Oschmann, P.33
Traube, H.34
Baumhackl, U.35
Salomonowitz, E.36
Paulson, O.37
Blumhardt, L.38
Cooper, A.39
Palace, J.40
Anslow, P.41
Perkin, G.D.42
Colquhoun, R.43
Rodriguez-Antiguedad, A.44
Ferrero-Collado, A.45
Asenjo-Garcia, B.46
Garcia-Merino, A.47
Viano, J.48
Arbizu-Urdiain, T.49
Capdevila I Cirera, A.50
Montalban, X.51
Rovira-Canellas, A.52
Seeldrayers, P.53
Hermanus, N.54
Medaer, R.55
Palmers, Y.56
Piazza, G.57
Bastianello, S.58
Durelli, D.59
Bergui, M.60
Fieschi, C.61
Bastianello, St.62
Scarlato, G.63
Comi, G.64
Jongen, P.J.H.65
Thijssen, H.O.M.66
Barkus, W.J.67
Leroux, G.68
Chan, B.69
Freedman, M.70
Avruch, L.71
Metz, L.72
Wallace, C.73
more..
-
18
-
-
77950258250
-
Ibudilast in relapsing-remitting multiple sclerosis: A neuroprotectant?
-
Barkhof, F. et al. Ibudilast in relapsing-remitting multiple sclerosis: A neuroprotectant? Neurology 74, 1033-1040 (2010).
-
(2010)
Neurology
, vol.74
, pp. 1033-1040
-
-
Barkhof, F.1
-
19
-
-
0036195802
-
+ T cells in multiple sclerosis: Results from an MRI-monitored phase II clinical trial
-
DOI 10.1002/ana.10146
-
Killestein, J. et al. Antibody-mediated suppression of Vß5.2/5.3+ T cells in multiple sclerosis: Results from an MRI-monitored phase II clinical trial. Ann. Neurol. 51, 467-474 (2002). (Pubitemid 34260776)
-
(2002)
Annals of Neurology
, vol.51
, Issue.4
, pp. 467-474
-
-
Killestein, J.1
Olsson, T.2
Wallstrom, E.3
Svenningsson, A.4
Khademi, M.5
Blumhardt, L.D.6
Fagius, J.7
Hillert, J.8
Landtblom, A.-M.9
Edenius, C.10
Arfors, L.11
Barkhof, F.12
Polman, C.H.13
-
20
-
-
41549132629
-
Ethics of placebo-controlled clinical trials in multiple sclerosis: A reassessment
-
DOI 10.1212/01.wnl.0000306410.84794.4d
-
Polman, C. H. et al. Ethics of placebo-controlled clinical trials in multiple sclerosis: A reassessment. Neurology 70, 1134-1140 (2008). (Pubitemid 351464771)
-
(2008)
Neurology
, vol.70
, Issue.13 PART 2
, pp. 1134-1140
-
-
Polman, C.H.1
Reingold, S.C.2
Barkhof, F.3
Calabresi, P.A.4
Clanet, M.5
Cohen, J.A.6
Cutter, G.R.7
Freedman, M.S.8
Kappos, L.9
Lublin, F.D.10
McFarland, H.F.11
Metz, L.M.12
Miller, A.E.13
Montalban, X.14
O'Connor, P.W.15
Panitch, H.16
Richert, J.R.17
Petkau, J.18
Schwid, S.R.19
Sormani, M.P.20
Thompson, A.J.21
Weinshenker, B.G.22
Wolinsky, J.S.23
more..
-
21
-
-
69949098534
-
250 μg or 500 μg interferon beta-1b versus 20 mg glatiramer acetate in relapsing-remitting multiple sclerosis: A prospective, randomised, multicentre study
-
O'Connor, P. et al. 250 μg or 500 μg interferon beta-1b versus 20 mg glatiramer acetate in relapsing-remitting multiple sclerosis: A prospective, randomised, multicentre study. Lancet Neurol. 8, 889-897 (2009).
-
(2009)
Lancet Neurol.
, vol.8
, pp. 889-897
-
-
O'Connor, P.1
-
22
-
-
51449101000
-
Comparison of subcutaneous interferon beta-1a with glatiramer acetate in patients with relapsing multiple sclerosis (the REbif vs Glatiramer Acetate in Relapsing MS Disease [REGARD] study): A multicentre, randomised, parallel, open-label trial
-
Mikol, D. D. et al. Comparison of subcutaneous interferon beta-1a with glatiramer acetate in patients with relapsing multiple sclerosis (the REbif vs Glatiramer Acetate in Relapsing MS Disease [REGARD] study): A multicentre, randomised, parallel, open-label trial. Lancet Neurol. 7, 903-914 (2008).
-
(2008)
Lancet Neurol.
, vol.7
, pp. 903-914
-
-
Mikol, D.D.1
-
23
-
-
78650158088
-
Assessing changes in relapse rates in multiple sclerosis
-
Inusah, S. et al. Assessing changes in relapse rates in multiple sclerosis. Mult. Scler. 16, 1414-1421 (2010).
-
(2010)
Mult. Scler
, vol.16
, pp. 1414-1421
-
-
Inusah, S.1
-
24
-
-
67649210709
-
MRI-The perfect surrogate marker for multiple sclerosis?
-
Barkhof, F. & Filippi, M. MRI-the perfect surrogate marker for multiple sclerosis? Nat. Rev. Neurol. 5, 182-183 (2009).
-
(2009)
Nat. Rev. Neurol
, vol.5
, pp. 182-183
-
-
Barkhof, F.1
Filippi, M.2
-
25
-
-
0024520844
-
Surrogate endpoints in clinical trials: Definition and operational criteria
-
Prentice, R. L. Surrogate endpoints in clinical trials: Definition and operational criteria. Stat. Med. 8, 431-440 (1989). (Pubitemid 19105891)
-
(1989)
Statistics in Medicine
, vol.8
, Issue.4
, pp. 431-440
-
-
Prentice, R.L.1
-
26
-
-
0037065813
-
MRI metrics as surrogate markers for clinical relapse rate in relapsing-remitting MS patients
-
Sormani, M. P. et al. MRI metrics as surrogate markers for clinical relapse rate in relapsing-remitting MS patients. Neurology 58, 417-421 (2002). (Pubitemid 34150916)
-
(2002)
Neurology
, vol.58
, Issue.3
, pp. 417-421
-
-
Sormani, M.P.1
Bruzzi, P.2
Comi, G.3
Filippi, M.4
-
27
-
-
0037883298
-
MRI metrics as surrogate endpoints for EDSS progression in SPMS patients treated with IFN β-1b
-
Sormani, M. P. et al. MRI metrics as surrogate endpoints for EDSS progression in SPMS patients treated with IFN ß-1b. Neurology 60, 1462-1466 (2003). (Pubitemid 36554807)
-
(2003)
Neurology
, vol.60
, Issue.9
, pp. 1462-1466
-
-
Sormani, M.P.1
Bruzzi, P.2
Beckmann, K.3
Wagner, K.4
Miller, D.H.5
Kappos, L.6
Filippi, M.7
-
28
-
-
80053424031
-
Magnetic resonance active lesions as individual-level surrogate for relapses in multiple sclerosis
-
Sormani, M. P. et al. Magnetic resonance active lesions as individual-level surrogate for relapses in multiple sclerosis. Mult. Scler. 17, 541-549 (2011).
-
(2011)
Mult. Scler
, vol.17
, pp. 541-549
-
-
Sormani, M.P.1
-
29
-
-
48349142161
-
Magnetic resonance imaging as a surrogate outcome for multiple sclerosis relapses
-
Petkau, J. et al. Magnetic resonance imaging as a surrogate outcome for multiple sclerosis relapses. Mult. Scler. 14, 770-778 (2008).
-
(2008)
Mult. Scler.
, vol.14
, pp. 770-778
-
-
Petkau, J.1
-
30
-
-
0030777744
-
Meta-analysis for the evaluation of potential surrogate markers
-
DOI 10.1002/(SICI)1097-0258(19970915)16:17<1965::AID-SIM630>3.0. CO;2-M
-
Daniels, M. & Hughes, M. D. Meta-analysis for the evaluation of potential surrogate markers. Stat. Med. 16, 1965-1982 (1997). (Pubitemid 27397267)
-
(1997)
Statistics in Medicine
, vol.16
, Issue.17
, pp. 1965-1982
-
-
Daniels, M.J.1
Hughes, M.D.2
-
31
-
-
12344270270
-
Assessing surrogates as trial endpoints using mixed models
-
DOI 10.1002/sim.1779
-
Korn, E. L., Albert, P. S. & McShane, L. M. Assessing surrogates as trial endpoints using mixed models. Stat. Med. 24, 163-182 (2005). (Pubitemid 40124164)
-
(2005)
Statistics in Medicine
, vol.24
, Issue.2
, pp. 163-182
-
-
Korn, E.L.1
Albert, P.S.2
McShane, L.M.3
-
32
-
-
65249154822
-
Magnetic resonance imaging as a potential surrogate for relapses in MS: A meta-analytic approach
-
Sormani, M. P. et al. Magnetic resonance imaging as a potential surrogate for relapses in MS: A meta-analytic approach. Ann. Neurol. 65, 268-275 (2009).
-
(2009)
Ann. Neurol.
, vol.65
, pp. 268-275
-
-
Sormani, M.P.1
-
33
-
-
80053399685
-
Magnetic resonance imaging as surrogate for clinical endpoints in multiple sclerosis: Data on novel oral drugs
-
Sormani, M., Bonzano, L., Roccatagliata, L. & de Stefano, N. Magnetic resonance imaging as surrogate for clinical endpoints in multiple sclerosis: Data on novel oral drugs. Mult. Scler. 17, 630-633 (2011).
-
(2011)
Mult. Scler
, vol.17
, pp. 630-633
-
-
Sormani, M.1
Bonzano, L.2
Roccatagliata, L.3
De Stefano, N.4
-
34
-
-
77955137180
-
Surrogate endpoints for EDSS worsening in multiple sclerosis. A meta-analytic approach
-
Sormani, M. P. et al. Surrogate endpoints for EDSS worsening in multiple sclerosis. A meta-analytic approach. Neurology 75, 302-309 (2010).
-
(2010)
Neurology
, vol.75
, pp. 302-309
-
-
Sormani, M.P.1
-
35
-
-
67349202499
-
High field MRI in the diagnosis of multiple sclerosis: High field-high yield?
-
Wattjes, M. P. & Barkhof, F. High field MRI in the diagnosis of multiple sclerosis: High field-high yield? Neuroradiology 51, 279-292 (2009).
-
(2009)
Neuroradiology
, vol.51
, pp. 279-292
-
-
Wattjes, M.P.1
Barkhof, F.2
-
36
-
-
20744442122
-
Intracortical lesions in multiple sclerosis: Improved detection with 3D double inversion-recovery MR imaging
-
DOI 10.1148/radiol.2361040450
-
Geurts, J. J. et al. Intracortical lesions in multiple sclerosis: Improved detection with 3D double inversion-recovery MR imaging. Radiology 236, 254-260 (2005). (Pubitemid 40853320)
-
(2005)
Radiology
, vol.236
, Issue.1
, pp. 254-260
-
-
Geurts, J.J.G.1
Pouwels, P.J.W.2
Uitdehaag, B.M.J.3
Polman, C.H.4
Barkhof, F.5
Castelijns, J.A.6
-
37
-
-
35348874326
-
Detection of cortical inflammatory lesions by double inversion recovery magnetic resonance imaging in patients with multiple sclerosis
-
Calabrese, M. et al. Detection of cortical inflammatory lesions by double inversion recovery magnetic resonance imaging in patients with multiple sclerosis. Arch. Neurol. 64, 416-422 (2007).
-
(2007)
Arch. Neurol.
, vol.64
, pp. 416-422
-
-
Calabrese, M.1
-
38
-
-
35349014120
-
Improved identification of intracortical lesions in multiple sclerosis with phase-sensitive inversion recovery in combination with fast double inversion recovery MR imaging
-
DOI 10.3174/ajnr.A0645
-
Nelson, F. et al. Improved identification of intracortical lesions in multiple sclerosis with phase-sensitive inversion recovery in combination with fast double inversion recovery MR imaging. AJNR Am. J. Neuroradiol. 28, 1645-1649 (2007). (Pubitemid 47598132)
-
(2007)
American Journal of Neuroradiology
, vol.28
, Issue.9
, pp. 1645-1649
-
-
Nelson, F.1
Poonawalla, A.H.2
Hou, P.3
Huang, F.4
Wolinsky, J.S.5
Narayana, P.A.6
-
39
-
-
52049111207
-
Multi-contrast, isotropic, single-slab 3D MR imaging in multiple sclerosis
-
Moraal, B. et al. Multi-contrast, isotropic, single-slab 3D MR imaging in multiple sclerosis. Eur. Radiol. 18, 2311-2320 (2008).
-
(2008)
Eur. Radiol.
, vol.18
, pp. 2311-2320
-
-
Moraal, B.1
-
40
-
-
79751535057
-
The Holy Grail in diagnostic neuroradiology: 3T or 3D?
-
Barkhof, F., Pouwels, P. J. & Wattjes, M. P. The Holy Grail in diagnostic neuroradiology: 3T or 3D? Eur. Radiol. 21, 449-456 (2011).
-
(2011)
Eur. Radiol
, vol.21
, pp. 449-456
-
-
Barkhof, F.1
Pouwels, P.J.2
Wattjes, M.P.3
-
41
-
-
57049154914
-
Spinal-cord MRI in multiple sclerosis: Conventional and nonconventional MR techniques
-
Bot, J. C. & Barkhof, F. Spinal-cord MRI in multiple sclerosis: Conventional and nonconventional MR techniques. Neuroimaging Clin. N. Am. 19, 81-99 (2009).
-
(2009)
Neuroimaging Clin. N. Am.
, vol.19
, pp. 81-99
-
-
Bot, J.C.1
Barkhof, F.2
-
42
-
-
79952501096
-
Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria
-
Polman, C. H. et al. Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria. Ann. Neurol. 69, 292-302 (2011).
-
(2011)
Ann. Neurol
, vol.69
, pp. 292-302
-
-
Polman, C.H.1
-
43
-
-
0029925782
-
Serial gadolinium-enhanced MRI of the brain and spinal cord in early relapsing-remitting multiple sclerosis
-
Thorpe, J. W. et al. Serial gadolinium-enhanced MRI of the brain and spinal cord in early relapsing-remitting multiple sclerosis. Neurology 46, 373-378 (1996). (Pubitemid 26081316)
-
(1996)
Neurology
, vol.46
, Issue.2
, pp. 373-378
-
-
Thorpe, J.W.1
Kidd, D.2
Moseley, I.F.3
Kendall, B.E.4
Thompson, A.J.5
MacManus, D.G.6
McDonald, W.I.7
Miller, D.H.8
-
44
-
-
0035083892
-
A modified protocol to improve the detection of enhancing brain and spinal cord lesions in multiple sclerosis
-
DOI 10.1007/s004150170229
-
Silver, N. C. et al. A modified protocol to improve the detection of enhancing brain and spinal cord lesions in multiple sclerosis. J. Neurol. 248, 215-224 (2001). (Pubitemid 32245498)
-
(2001)
Journal of Neurology
, vol.248
, Issue.3
, pp. 215-224
-
-
Silver, N.C.1
Good, C.D.2
Sormani, M.P.3
MacManus, D.G.4
Thompson, A.J.5
Filippi, M.6
Miller, D.H.7
-
45
-
-
8944248824
-
Spinal cord atrophy and disability in multiple sclerosis. A new reproducible and sensitive MRI method with potential to monitor disease progression
-
DOI 10.1093/brain/119.3.701
-
Losseff, N. A. et al. Spinal cord atrophy and disability in multiple sclerosis. A new reproducible and sensitive MRI method with potential to monitor disease progression. Brain 119, 701-708 (1996). (Pubitemid 26237169)
-
(1996)
Brain
, vol.119
, Issue.3
, pp. 701-708
-
-
Losseff, N.A.1
Webb, S.L.2
O'Riordan, J.I.3
Page, R.4
Wang, L.5
Barker, G.J.6
Tofts, P.S.7
McDonald, W.I.8
Miller, D.H.9
Thompson, A.J.10
-
46
-
-
1842845857
-
The effect of the neuroprotective agent riluzole on MRI parameters in primary progressive multiple sclerosis: A pilot study
-
DOI 10.1191/1352458502ms849xx
-
Kalkers, N. F., Barkhof, F., Bergers, E., van Schijndel, R. & Polman, C. H. The effect of the neuroprotective agent riluzole on MRI parameters in primary progressive multiple sclerosis: A pilot study. Mult. Scler. 8, 532-533 (2002). (Pubitemid 35396406)
-
(2002)
Multiple Sclerosis
, vol.8
, Issue.6
, pp. 532-533
-
-
Kalkers, N.F.1
Barkhof, F.2
Bergers, E.3
Van Schijndel, R.4
Polman, C.H.5
-
47
-
-
0030754518
-
Sensitivity of contrast enhanced MRI in multiple sclerosis. Effects of gadolinium dose, magnetization transfer contrast and delayed imaging
-
DOI 10.1093/brain/120.7.1149
-
Silver, N. C. et al. Sensitivity of contrast enhanced MRI in multiple sclerosis. Effects of gadolinium dose, magnetization transfer contrast and delayed imaging. Brain 120, 1149-1161 (1997). (Pubitemid 27285734)
-
(1997)
Brain
, vol.120
, Issue.7
, pp. 1149-1161
-
-
Silver, N.C.1
Good, C.D.2
Barker, G.J.3
MacManus, D.G.4
Thompson, A.J.5
Moseley, I.F.6
McDonald, W.I.7
Miller, D.H.8
-
48
-
-
45249107267
-
Effect of laquinimod on MRI-monitored disease activity in patients with relapsing-remitting multiple sclerosis: A multicentre, randomised, double-blind, placebo-controlled phase IIb study
-
DOI 10.1016/S0140-6736(08)60918-6, PII S0140673608609186
-
Comi, G. et al. Effect of laquinimod on MRI-monitored disease activity in patients with relapsing-remitting multiple sclerosis: A multicentre, randomised, double-blind, placebo-controlled phase IIb study. Lancet 371, 2085-2092 (2008). (Pubitemid 351842581)
-
(2008)
The Lancet
, vol.371
, Issue.9630
, pp. 2085-2092
-
-
Comi, G.1
Pulizzi, A.2
Rovaris, M.3
Abramsky, O.4
Arbizu, T.5
Boiko, A.6
Gold, R.7
Havrdova, E.8
Komoly, S.9
Selmaj, K.10
Sharrack, B.11
Filippi, M.12
-
49
-
-
33750597937
-
MR imaging of relapsing multiple sclerosis patients using ultra-small-particle iron oxide and compared with gadolinium
-
Dousset, V. et al. MR imaging of relapsing multiple sclerosis patients using ultra-small-particle iron oxide and compared with gadolinium. AJNR Am. J. Neuroradiol. 27, 1000-1005 (2006). (Pubitemid 44897675)
-
(2006)
American Journal of Neuroradiology
, vol.27
, Issue.5
, pp. 1000-1005
-
-
Dousset, V.1
Brochet, B.2
Deloire, M.S.A.3
Lagoarde, L.4
Barroso, B.5
Caille, J.-M.6
Petry, K.G.7
-
50
-
-
39749086937
-
Pluriformity of inflammation in multiple sclerosis shown by ultra-small iron oxide particle enhancement
-
DOI 10.1093/brain/awn009
-
Vellinga, M. M. et al. Pluriformity of inflammation in multiple sclerosis shown by ultra-small iron oxide particle enhancement. Brain 131, 800-807 (2008). (Pubitemid 351294725)
-
(2008)
Brain
, vol.131
, Issue.3
, pp. 800-807
-
-
Vellinga, M.M.1
Oude Engberink, R.D.2
Seewann, A.3
Pouwels, P.J.W.4
Wattjes, M.P.5
Van Der Pol, S.M.A.6
Pering, C.7
Polman, C.H.8
De Vries, H.E.9
Geurts, J.J.G.10
Barkhof, F.11
-
51
-
-
0031442396
-
Improving interobserver variation in reporting gadolinium-enhanced MRI lesions in multiple sclerosis
-
Barkhof, F. et al. Improving interobserver variation in reporting gadolinium-enhanced MRI lesions in multiple sclerosis. Neurology. 49, 1682-1688 (1997). (Pubitemid 28015137)
-
(1997)
Neurology
, vol.49
, Issue.6
, pp. 1682-1688
-
-
Barkhof, F.1
-
52
-
-
0033404650
-
Visual analysis of serial T2-weighted MRI in multiple sclerosis: Intra- and interobserver reproducibility
-
DOI 10.1007/s002340050860
-
Molyneux, P. D. et al. Visual analysis of serial T2-weighted MRI in multiple sclerosis: Intra- and interobserver reproducibility. Neuroradiology 41, 882-888 (1999). (Pubitemid 30000290)
-
(1999)
Neuroradiology
, vol.41
, Issue.12
, pp. 882-888
-
-
Molyneux, P.D.1
Miller, D.H.2
Filippi, M.3
Yousry, T.A.4
Radu, E.W.5
Ader, H.J.6
Barkhof, F.7
-
53
-
-
0032714913
-
Multiple sclerosis: Interobserver agreement in reporting active lesions on serial brain MRI using conventional spin echo, fast spin echo, fast fluid-attenuated inversion recovery and post-contrast T1-weighted images
-
DOI 10.1007/s004150050483
-
Rovaris, M. et al. Multiple sclerosis: Interobserver agreement in reporting active lesions on serial brain MRI using conventional spin echo, fast spin echo, fast fluid-attenuated inversion recovery and post-contrast T1-weighted images. J. Neurol. 246, 920-925 (1999). (Pubitemid 29512162)
-
(1999)
Journal of Neurology
, vol.246
, Issue.10
, pp. 920-925
-
-
Rovaris, M.1
Barkhof, F.2
Bastianello, S.3
Gasperini, C.4
Tubridy, N.5
Yousry, T.A.6
Sormani, M.P.7
Viti, B.8
Miller, D.H.9
Filippi, M.10
-
54
-
-
0031930763
-
Effect of training and different measurement strategies on the reproducibility of brain MRI lesion load measurements in multiple sclerosis
-
Filippi, M. et al. Effect of training and different measurement strategies on the reproducibility of brain MRI lesion load measurements in multiple sclerosis. Neurology 50, 238-244 (1998). (Pubitemid 28106048)
-
(1998)
Neurology
, vol.50
, Issue.1
, pp. 238-244
-
-
Filippi, M.1
Gawne-Cain, M.L.2
Gasperini, C.3
Vanwaesberghe, J.H.4
Grimaud, J.5
Barkhof, F.6
Sormani, M.P.7
Miller, D.H.8
-
55
-
-
0031987382
-
A nonparametric method for automatic correction of intensity nonuniformity in mri data
-
PII S0278006298031516
-
Sled, J. G., Zijdenbos, A. P. & Evans, A. C. A nonparametric method for automatic correction of intensity nonuniformity in MRI data. IEEE Trans. Med. Imaging 17, 87-97 (1998). (Pubitemid 128742012)
-
(1998)
IEEE Transactions on Medical Imaging
, vol.17
, Issue.1
, pp. 87-97
-
-
Sied, J.G.1
Zijdenbos, A.P.2
Evans, A.C.3
-
56
-
-
0142260969
-
A fully automatic and robust brain MRI tissue classification method
-
DOI 10.1016/S1361-8415(03)00037-9
-
Cocosco, C. A., Zijdenbos, A. P. & Evans, A. C. A fully automatic and robust brain MRI tissue classification method. Med. Image Anal. 7, 513-527 (2003). (Pubitemid 37327991)
-
(2003)
Medical Image Analysis
, vol.7
, Issue.4
, pp. 513-527
-
-
Cocosco, C.A.1
Zijdenbos, A.P.2
Evans, A.C.3
-
57
-
-
7044260964
-
Advances in functional and structural MR image analysis and implementation as FSL
-
DOI 10.1016/j.neuroimage.2004.07.051, PII S1053811904003933, Mathematics in Brain Imaging
-
Smith, S. M. et al. Advances in functional and structural MR image analysis and implementation as FSL. Neuroimage 23 (Suppl. 1), S208-S219 (2004). (Pubitemid 39421720)
-
(2004)
NeuroImage
, vol.23
, Issue.SUPPL. 1
-
-
Smith, S.M.1
Jenkinson, M.2
Woolrich, M.W.3
Beckmann, C.F.4
Behrens, T.E.J.5
Johansen-Berg, H.6
Bannister, P.R.7
De Luca, M.8
Drobnjak, I.9
Flitney, D.E.10
Niazy, R.K.11
Saunders, J.12
Vickers, J.13
Zhang, Y.14
De Stefano, N.15
Brady, J.M.16
Matthews, P.M.17
-
58
-
-
36549088081
-
Incorporating domain knowledge into the fuzzy connectedness framework: Application to brain lesion volume estimation in multiple sclerosis
-
Horsfield, M. A. et al. Incorporating domain knowledge into the fuzzy connectedness framework: Application to brain lesion volume estimation in multiple sclerosis. IEEE Trans. Med. Imaging 26, 1670-17680 (2007).
-
(2007)
IEEE Trans. Med. Imaging
, vol.26
, pp. 1670-17680
-
-
Horsfield, M.A.1
-
59
-
-
64949166881
-
Evaluation of 14 nonlinear deformation algorithms applied to human brain MRI registration
-
Klein, A. et al. Evaluation of 14 nonlinear deformation algorithms applied to human brain MRI registration. Neuroimage 46, 786-802 (2009).
-
(2009)
Neuroimage
, vol.46
, pp. 786-802
-
-
Klein, A.1
-
60
-
-
77950375277
-
Improved detection of active multiple sclerosis lesions: 3D subtraction imaging
-
Moraal, B. et al. Improved detection of active multiple sclerosis lesions: 3D subtraction imaging. Radiology 255, 154-163 (2010).
-
(2010)
Radiology
, vol.255
, pp. 154-163
-
-
Moraal, B.1
-
61
-
-
77951750526
-
Long-interval T2-weighted subtraction magnetic resonance imaging: A powerful new outcome measure in multiple sclerosis trials
-
Moraal, B. et al. Long-interval T2-weighted subtraction magnetic resonance imaging: A powerful new outcome measure in multiple sclerosis trials. Ann. Neurol. 67, 667-675 (2010).
-
(2010)
Ann. Neurol
, vol.67
, pp. 667-675
-
-
Moraal, B.1
-
62
-
-
68349107070
-
Imaging outcomes for neuroprotection and repair in multiple sclerosis trials
-
Barkhof, F., Calabresi, P. A., Miller, D. H. & Reingold, S. C. Imaging outcomes for neuroprotection and repair in multiple sclerosis trials. Nat. Rev. Neurol. 5, 256-266 (2009).
-
(2009)
Nat. Rev. Neurol.
, vol.5
, pp. 256-266
-
-
Barkhof, F.1
Calabresi, P.A.2
Miller, D.H.3
Reingold, S.C.4
-
63
-
-
47549113346
-
Mechanisms of action of disease-modifying agents and brain volume changes in multiple sclerosis
-
Zivadinov, R. et al. Mechanisms of action of disease-modifying agents and brain volume changes in multiple sclerosis. Neurology 71, 136-144 (2008).
-
(2008)
Neurology
, vol.71
, pp. 136-144
-
-
Zivadinov, R.1
-
64
-
-
77953476309
-
Lamotrigine for neuroprotection in secondary progressive multiple sclerosis: A randomised, double-blind, placebo-controlled, parallel-group trial
-
Kapoor, R. et al. Lamotrigine for neuroprotection in secondary progressive multiple sclerosis: A randomised, double-blind, placebo-controlled, parallel-group trial. Lancet Neurol. 9, 681-688 (2010).
-
(2010)
Lancet Neurol.
, vol.9
, pp. 681-688
-
-
Kapoor, R.1
-
65
-
-
34247513840
-
MRI outcomes in a placebo-controlled trial of natalizumab in relapsing MS
-
DOI 10.1212/01.wnl.0000260064.77700.fd, PII 0000611420070424000012
-
Miller, D. H. et al. MRI outcomes in a placebo-controlled trial of natalizumab in relapsing MS. Neurology 68, 1390-1401 (2007). (Pubitemid 46659091)
-
(2007)
Neurology
, vol.68
, Issue.17
, pp. 1390-1401
-
-
Miller, D.H.1
Soon, D.2
Fernando, K.T.3
MacManus, D.G.4
Barker, G.J.5
Yousry, T.A.6
Fisher, E.7
O'Connor, P.W.8
Phillips, J.T.9
Polman, C.H.10
Kappos, L.11
Hutchinson, M.12
Havrdova, E.13
Lublin, F.D.14
Giovannoni, G.15
Wajgt, A.16
Rudick, R.17
Lynn, F.18
Panzara, M.A.19
Sandrock, A.W.20
more..
-
66
-
-
41549134730
-
Regression of new gadolinium enhancing lesion activity in relapsing-remitting multiple sclerosis
-
DOI 10.1212/01.wnl.0000285426.73143.f7
-
Zhao, Y., Traboulsee, A., Petkau, A. J. & Li, D. Regression of new gadolinium enhancing lesion activity in relapsing-remitting multiple sclerosis. Neurology 70, 1092-1097 (2008). (Pubitemid 351464765)
-
(2008)
Neurology
, vol.70
, Issue.13 PART 2
, pp. 1092-1097
-
-
Zhao, Y.1
Traboulsee, A.2
Petkau, A.J.3
Li, D.4
-
67
-
-
0033081690
-
Modelling MRI enhancing lesion counts in multiple sclerosis using a negative binomial model: Implications for clinical trials
-
DOI 10.1016/S0022-510X(99)00015-5, PII S0022510X99000155
-
Sormani, M. P. et al. Modelling MRI enhancing lesion counts in multiple sclerosis using a negative binomial model: Implications for clinical trials. J. Neurol. Sci. 163, 74-80 (1999). (Pubitemid 29155420)
-
(1999)
Journal of the Neurological Sciences
, vol.163
, Issue.1
, pp. 74-80
-
-
Sormani, M.P.1
Bruzzi, P.2
Miller, D.H.3
Gasperini, C.4
Barkhof, F.5
Filippi, M.6
-
68
-
-
76149140914
-
Oral fingolimod or intramuscular interferon for relapsing multiple sclerosis
-
Cohen, J. A. et al. Oral fingolimod or intramuscular interferon for relapsing multiple sclerosis. N. Engl. J. Med. 362, 402-415 (2010).
-
(2010)
N. Engl. J. Med.
, vol.362
, pp. 402-415
-
-
Cohen, J.A.1
-
69
-
-
76149093586
-
A placebo-controlled trial of oral fingolimod in relapsing multiple sclerosis
-
Kappos, L. et al. A placebo-controlled trial of oral fingolimod in relapsing multiple sclerosis. N. Engl. J. Med. 362, 387-401 (2010).
-
(2010)
N. Engl. J. Med.
, vol.362
, pp. 387-401
-
-
Kappos, L.1
-
70
-
-
27644443197
-
Predicting gadolinium, enhancement status in MS patients eligible for randomized clinical trials
-
DOI 10.1212/01.wnl.0000183149.87975.32
-
Barkhof, F. et al. Predicting gadolinium enhancement status in MS patients eligible for randomized clinical trials. Neurology 65, 1447-1454 (2005). (Pubitemid 41552778)
-
(2005)
Neurology
, vol.65
, Issue.9
, pp. 1447-1454
-
-
Barkhof, F.1
Held, U.2
Simon, J.H.3
Daumer, M.4
Fazekas, F.5
Filippi, M.6
Frank, J.A.7
Kappos, L.8
Li, D.9
Menzler, S.10
Miller, D.H.11
Petkau, J.12
Wolinsky, J.13
-
71
-
-
0034727059
-
Intramuscular interferon beta-1a therapy initiated during a first demyelinating event in multiple sclerosis. CHAMPS Study Group
-
Jacobs, L. D. et al. Intramuscular interferon beta-1a therapy initiated during a first demyelinating event in multiple sclerosis. CHAMPS Study Group. N. Engl. J. Med. 343, 898-904 (2000).
-
(2000)
N. Engl. J. Med.
, vol.343
, pp. 898-904
-
-
Jacobs, L.D.1
-
72
-
-
34548635873
-
Magnetic resonance imaging effects of interferon beta-1b in the BENEFIT study: Integrated 2-year results
-
DOI 10.1001/archneur.64.9.1292
-
Barkhof, F. et al. Magnetic resonance imaging effects of interferon beta-1b in the BENEFIT study: Integrated 2-year results. Arch. Neurol. 64, 1292-1298 (2007). (Pubitemid 47403084)
-
(2007)
Archives of Neurology
, vol.64
, Issue.9
, pp. 1292-1298
-
-
Barkhof, F.1
Polman, C.H.2
Radue, E.-W.3
Kappos, L.4
Freedman, M.S.5
Edan, G.6
Hartung, H.-P.7
Miller, D.H.8
Montalban, X.9
Poppe, P.10
De Vos, M.11
Lasri, F.12
Bauer, L.13
Dahms, S.14
Wagner, K.15
Pohl, C.16
Sandbrink, R.17
-
73
-
-
73649090430
-
MRI safety update 2008: Part 1, MRI contrast agents and nephrogenic systemic fibrosis. AJR Am. J. Roentgenol. 191, 1129-1139 (2008). 74. Leiner, T. & Kucharczyk, W. NSF prevention in clinical practice: Summary of recommendations and guidelines in the United States, Canada, and Europe
-
Shellock, F. G. & Spinazzi, A. MRI safety update 2008: Part 1, MRI contrast agents and nephrogenic systemic fibrosis. AJR Am. J. Roentgenol. 191, 1129-1139 (2008). 74. Leiner, T. & Kucharczyk, W. NSF prevention in clinical practice: Summary of recommendations and guidelines in the United States, Canada, and Europe. J. Magn. Reson. Imaging 30, 1357-1363 (2009).
-
(2009)
J. Magn. Reson. Imaging
, vol.30
, pp. 1357-1363
-
-
Shellock, F.G.1
Spinazzi, A.2
-
74
-
-
33644605483
-
Evaluation of patients treated with natalizumab for progressive multifocal leukoencephalopathy
-
Yousry, T. A. et al. Evaluation of patients treated with natalizumab for progressive multifocal leukoencephalopathy. N. Engl. J. Med. 354, 924-933 (2006).
-
(2006)
N. Engl. J. Med
, vol.354
, pp. 924-933
-
-
Yousry, T.A.1
-
75
-
-
84862907806
-
Evaluation of safety monitoring guidelines based on MRI lesion activity in multiple sclerosis
-
in press
-
Riddell, C. A. et al. Evaluation of safety monitoring guidelines based on MRI lesion activity in multiple sclerosis. Neurology (in press).
-
Neurology
-
-
Riddell, C.A.1
-
76
-
-
70449418132
-
Rituximab in patients with primary progressive multiple sclerosis: Results of a randomized double-blind placebo-controlled multicenter trial
-
Hawker, K. et al. Rituximab in patients with primary progressive multiple sclerosis: Results of a randomized double-blind placebo-controlled multicenter trial. Ann. Neurol. 66, 460-471 (2009).
-
(2009)
Ann. Neurol
, vol.66
, pp. 460-471
-
-
Hawker, K.1
-
77
-
-
0033472729
-
Effect of interferon-ß1b on magnetic resonance imaging outcomes in secondary progressive multiple sclerosis: Results of a European multicenter, randomized, double-blind, placebo-controlled trial. European Study Group on Interferon-ß1b in secondary progressive multiple sclerosis
-
Miller, D. H. et al. Effect of interferon-ß1b on magnetic resonance imaging outcomes in secondary progressive multiple sclerosis: Results of a European multicenter, randomized, double-blind, placebo-controlled trial. European Study Group on Interferon-ß1b in secondary progressive multiple sclerosis. Ann. Neurol. 46, 850-859 (1999).
-
(1999)
Ann. Neurol.
, vol.46
, pp. 850-859
-
-
Miller, D.H.1
-
78
-
-
0034951507
-
1 hypointense lesions in secondary progressive multiple sclerosis: Effect of interferon beta-1b treatment
-
Barkhof, F. et al. T1-hypointense lesions in secondary progressive multiple sclerosis: Effect of interferon beta-1b treatment. Brain 124, 1396-1402 (2001). (Pubitemid 32606100)
-
(2001)
Brain
, vol.124
, Issue.7
, pp. 1396-1402
-
-
Barkhof, F.1
Van Waesberghe, J.-H.T.M.2
Filippi, M.3
Yousry, T.4
Miller, D.H.5
Hahn, D.6
Thompson, A.J.7
Kappos, L.8
Brex, P.9
Pozzilli, C.10
Polman, C.H.11
-
79
-
-
79952736410
-
Evolution of multiple sclerosis treatment: Next generation therapies meet next generation efficacy criteria
-
Hartung, H. P. & Aktas, O. Evolution of multiple sclerosis treatment: Next generation therapies meet next generation efficacy criteria. Lancet Neurol. 10, 293-295 (2011).
-
(2011)
Lancet Neurol.
, vol.10
, pp. 293-295
-
-
Hartung, H.P.1
Aktas, O.2
|