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Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 1, 2012, Pages 110-114

Design, synthesis and antitumor activity of 4-aminoquinazoline derivatives targeting VEGFR-2 tyrosine kinase

(7) Yu, Bing a,b Tang, Li Da b Li, Yi Liang b Song, Shu Hui c Ji, Xiao Liang c Lin, Mu Sen c Wu, Chun Fu a

a SHENYANG PHARMACEUTICAL UNIVERSITY (China)

b TIANJIN INSTITUTE OF PHARMACEUTICAL RESEARCH (China)

c TIANJIN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE (China)

Author keywords

4 Aminoquinazolines; Synthesis; VEGFR 2

Indexed keywords

2,4 DIAMINOQUINAZOLINE DERIVATIVE; ANTINEOPLASTIC AGENT; LINIFANIB; SORAFENIB; VANDETANIB; VASCULOTROPIN RECEPTOR 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL STRAIN HEPG2; CRYSTAL STRUCTURE; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VIVO STUDY; MOUSE; NONHUMAN; STRUCTURE ACTIVITY RELATION; TUMOR XENOGRAFT;

ANIMALS; ANTINEOPLASTIC AGENTS; CHEMISTRY, PHARMACEUTICAL; DRUG DESIGN; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME INHIBITORS; HEP G2 CELLS; HUMANS; INHIBITORY CONCENTRATION 50; MICE; MICE, NUDE; MODELS, CHEMICAL; NEOPLASM TRANSPLANTATION; PIPERIDINES; QUINAZOLINES; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

MUS;

EID: 84655162073 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2011.11.061 Document Type: Article

Times cited : (25)

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