Effects of SMYD3 over-expression on cell cycle acceleration and cell proliferation in MDA-MB-231 human breast cancer cells

Medical Oncology

Volumn 28, Issue SUPPL. 1, 2011, Pages

  Ren, Tian Nian ^a   Wang, Jing Song ^a   He, Yun Mian ^a   Xu, Chang Liang ^a   Wang, Shu Zhen ^a   Xi, Tao ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Cell cycle; Cell proliferation; SMYD3

Indexed keywords

CYCLIN D1; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; HISTONE METHYLTRANSFERASE; MESSENGER RNA; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P21; PROTEIN P53; REGULATOR PROTEIN; SET AND MYND DOMAIN CONTAINING PROTEIN 3; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BREAST CELL; CANCER CELL; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE PROGRESSION; CELL CYCLE S PHASE; CELL GROWTH; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

EID: 84555218805     PISSN: 13570560     EISSN: 1559131X     Source Type: Journal    
DOI: 10.1007/s12032-010-9718-6     Document Type: Article

References (26)

1. A Lennartsson K Ekwall 2009 Histone modification patterns and epigenetic codes Biochim Biophys Acta 1790 9 863 868
2. JL Hu BO Zhou RR Zhang KL Zhang JQ Zhou GL Xu 2009 The N-terminus of histone H3 is required for de novo DNA methylation in chromatin Proc Natl Acad Sci USA 106 52 22187 22192
3. MA Hamon E Batsche B Regnault TN Tham S Seveau C Muchardt 2007 Histone modifications induced by a family of bacterial toxins Proc Natl Acad Sci USA 104 33 13467 13472 (Pubitemid 47293968)
4. B Schmeck W Beermann V van Laak J Zahlten B Opitz M Witzenrath 2005 Intracellular bacteria differentially regulated endothelial cytokine release by MAPK-dependent histone modification J Immunol 175 5 2843 2850 (Pubitemid 41170501)
5. JM Kim TK To J Ishida T Morosawa M Kawashima A Matsui 2008 Alterations of lysine modifications on the histone H3 N-tail under drought stress conditions in Arabidopsis thaliana Plant Cell Physiol 49 10 1580 1588
6. S Varambally SM Dhanasekaran M Zhou TR Barrette C Kumar-Sinha MG Sanda 2002 The polycomb group protein EZH2 is involved in progression of prostate cancer Nature 419 6907 624 629
7. R Hamamoto Y Furukawa M Morita Y Iimura FP Silva M Li 2004 SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells Nat Cell Biol 6 8 731 740 (Pubitemid 39144478)
8. R Hamamoto FP Silva M Tsuge T Nishidate T Katagiri Y Nakamura 2006 Enhanced SMYD3 expression is essential for the growth of breast cancer cells Cancer Sci 97 2 113 118 (Pubitemid 43379478)
9. XG Luo JN Zou SZ Wang TC Zhang T Xi 2010 Novobiocin decreases SMYD3 expression and inhibits the migration of MDA-MB-231 human breast cancer cells IUBMB Life 62 3 194 199
10. JN Zou SZ Wang JS Yang XG Luo JH Xie T Xi 2009 Knockdown of SMYD3 by RNA interference down-regulates c-Met expression and inhibits cells migration and invasion induced by HGF Cancer Lett 280 1 78 85
11. SZ Wang XG Luo J Shen JN Zou YH Lu T Xi 2008 Knockdown of SMYD3 by RNA interference inhibits cervical carcinoma cell growth and invasion in vitro BMB Rep 41 4 294 299 (Pubitemid 351656923)
12. XG Luo Y Ding QF Zhou L Ye SZ Wang T Xi 2007 SET and MYND domain-containing protein 3 decreases sensitivity to dexamethasone and stimulates cell adhesion and migration in NIH3T3 cells J Biosci Bioeng 103 5 444 450 (Pubitemid 46991401)
13. RJ Sims 3rd D Reinberg 2004 From chromatin to cancer: a new histone lysine methyltransferase enters the mix Nat Cell Biol 6 8 685 687 (Pubitemid 39144469)
14. Miremadi A, Oestergaard MZ, Pharoah PD, Caldas C. Cancer genetics of epigenetic genes. Hum Mol Genet. 2007;16 Spec No 1:R28-49. (Pubitemid 47241841)
15. PA Wade 2001 Methyl CpG-binding proteins and transcriptional repression Bioessays 23 12 1131 1137
16. JR Dobosy EU Selker 2001 Emerging connections between DNA methylation and histone acetylation Cell Mol Life Sci 58 5-6 721 727 (Pubitemid 32553029)
17. Wang Y, Fischle W, Cheung W, Jacobs S, Khorasanizadeh S, Allis CD. Beyond the double helix: writing and reading the histone code. Novartis Found Symp. 2004;259:3-17 (discussion -21, 163-9).
18. M Esteller 2007 Cancer epigenomics: DNA methylomes and histone-modification maps Nat Rev Genet 8 4 286 298 (Pubitemid 46439286)
19. M Suzuki H Shigematsu DS Shames N Sunaga T Takahashi N Shivapurkar 2007 Methylation and gene silencing of the Ras-related GTPase gene in lung and breast cancers Ann Surg Oncol 14 4 1397 1404 (Pubitemid 46536799)
20. P Zhao W Zhong X Ying Z Yuan J Fu Z Zhou 2008 Manganese chloride-induced G0/G1 and S phase arrest in A549 cells Toxicology 250 1 39 46
21. AJ Obaya JM Sedivy 2002 Regulation of cyclin-Cdk activity in mammalian cells Cell Mol Life Sci 59 1 126 142 (Pubitemid 34117361)
22. S Cory JM Adams 2002 The Bcl2 family: regulators of the cellular life-or-death switch Nat Rev Cancer 2 9 647 656 (Pubitemid 37328916)
23. B Antonsson 2001 Bax and other pro-apoptotic Bcl-2 family "killer-proteins" and their victim the mitochondrion Cell Tissue Res 306 3 347 361 (Pubitemid 33139893)
24. S Takayama T Sato S Krajewski K Kochel S Irie JA Millan 1995 Cloning and functional analysis of BAG-1: a novel Bcl-2-binding protein with anti-cell death activity Cell 80 2 279 284
25. HG Wang S Takayama UR Rapp JC Reed 1996 Bcl-2 interacting protein, BAG-1, binds to and activates the kinase Raf-1 Proc Natl Acad Sci USA 93 14 7063 7068
26. J Downward 1998 Ras signalling and apoptosis Curr Opin Genet Dev 8 1 49 54 (Pubitemid 28122140)