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Volumn 821, Issue , 2012, Pages 317-327

Exploring functional in vivo consequences of the selective genetic ablation of mTOR signaling in T helper lymphocytes

Author keywords

CD4; mTOR; T cells

Indexed keywords

CYTOKINE; MTOR PROTEIN, HUMAN; RAPAMYCIN; TARGET OF RAPAMYCIN KINASE;

EID: 84555189464     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-61779-430-8_20     Document Type: Article
Times cited : (6)

References (13)
  • 1
    • 33747819801 scopus 로고    scopus 로고
    • MTOR and cancer: Insights into a complex relationship
    • DOI 10.1038/nrc1974, PII NRC1974
    • Sabatini, D. M. (2006) mTOR and cancer: insights into a complex relationship, Nat Rev Cancer 6, 729-734. (Pubitemid 44286004)
    • (2006) Nature Reviews Cancer , vol.6 , Issue.9 , pp. 729-734
    • Sabatini, D.M.1
  • 4
    • 74649085700 scopus 로고    scopus 로고
    • The mTOR kinase determines effector versus memory CD8+ T cell fate by regulating the expression of transcription factors T-bet and Eomesodermin
    • Rao, R. R., Li, Q., Odunsi, K., and Shrikant, P. A. The mTOR kinase determines effector versus memory CD8+ T cell fate by regulating the expression of transcription factors T-bet and Eomesodermin, Immunity 32, 67-78.
    • Immunity , vol.32 , pp. 67-78
    • Rao, R.R.1    Li, Q.2    Odunsi, K.3    Shrikant, P.A.4
  • 5
    • 35748956420 scopus 로고    scopus 로고
    • Rapamycin inhibits differentiation of Th17 cells and promotes generation of FoxP3+ T regulatory cells
    • DOI 10.1016/j.intimp.2007.08.027, PII S1567576907002809
    • Kopf, H., de la Rosa, G. M., Howard, O. M., and Chen, X. (2007) Rapamycin inhibits differentiation of Th17 cells and promotes generation of FoxP3+ T regulatory cells, Int Immunopharmacol 7, 1819-1824. (Pubitemid 350046435)
    • (2007) International Immunopharmacology , vol.7 , Issue.13 , pp. 1819-1824
    • Kopf, H.1    De La Rosa, G.M.2    Howard, O.M.Z.3    Chen, X.4
  • 6
    • 33745861719 scopus 로고    scopus 로고
    • + T cells
    • Valmori, D., Tosello, V., Souleimanian, N. E., Godefroy, E., Scotto, L., Wang, Y., and Ayyoub, M. (2006) Rapamycin-mediated enrichment of T cells with regulatory activity in stimulated CD4+ T cell cultures is not due to the selective expansion of naturally occurring regulatory T cells but to the induction of regulatory functions in conventional CD4+ T cells, J Immunol 177, 944-949. (Pubitemid 44036595)
    • (2006) Journal of Immunology , vol.177 , Issue.2 , pp. 944-949
    • Valmori, D.1    Tosello, V.2    Souleimanian, N.E.3    Godefroy, E.4    Scotto, L.5    Wang, Y.6    Ayyoub, M.7
  • 7
    • 20444373376 scopus 로고    scopus 로고
    • + regulatory T cells
    • DOI 10.1182/blood-2004-10-3932
    • Battaglia, M., Stabilini, A., and Roncarolo, M. G. (2005) Rapamycin selectively expands CD4 + CD25 + FoxP3+ regulatory T cells, Blood 105, 4743-4748. (Pubitemid 40807298)
    • (2005) Blood , vol.105 , Issue.12 , pp. 4743-4748
    • Battaglia, M.1    Stabilini, A.2    Roncarolo, M.-G.3
  • 8
    • 46649087778 scopus 로고    scopus 로고
    • Nogo-66 promotes the differentiation of neural progenitors into astroglial lineage cells through mTOR-STAT3 pathway
    • Wang, B., Xiao, Z., Chen, B., Han, J., Gao, Y., Zhang, J., Zhao, W., Wang, X., and Dai, J. (2008) Nogo-66 promotes the differentiation of neural progenitors into astroglial lineage cells through mTOR-STAT3 pathway, PLoS One 3, e1856.
    • (2008) PLoS One , vol.3
    • Wang, B.1    Xiao, Z.2    Chen, B.3    Han, J.4    Gao, Y.5    Zhang, J.6    Zhao, W.7    Wang, X.8    Dai, J.9
  • 9
    • 34347220473 scopus 로고    scopus 로고
    • Defining the Role of mTOR in Cancer
    • DOI 10.1016/j.ccr.2007.05.008, PII S1535610807001511
    • Guertin, D. A., and Sabatini, D. M. (2007) Defining the role of mTOR in cancer, Cancer Cell 12, 9-22. (Pubitemid 47001784)
    • (2007) Cancer Cell , vol.12 , Issue.1 , pp. 9-22
    • Guertin, D.A.1    Sabatini, D.M.2
  • 11
    • 68149096799 scopus 로고    scopus 로고
    • The pharmacology of mTOR inhibition
    • Guertin, D. A., and Sabatini, D. M. (2009) The pharmacology of mTOR inhibition, Sci Signal 2, pe24.
    • (2009) Sci Signal , vol.2 , pp. 24
    • Guertin, D.A.1    Sabatini, D.M.2
  • 13
    • 67650553603 scopus 로고    scopus 로고
    • MTOR: Taking cues from the immune microenvironment
    • Delgoffe, G. M., and Powell, J. D. (2009) mTOR: taking cues from the immune microenvironment, Immunology 127, 459-465.
    • (2009) Immunology , vol.127 , pp. 459-465
    • Delgoffe, G.M.1    Powell, J.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.