Stepwise proteolytic activation of type I procollagen to collagen within the secretory pathway of tendon fibroblasts in situ

Biochemical Journal

Volumn 441, Issue 2, 2012, Pages 707-717

  Canty Laird, Elizabeth G ^a   Lu, Yinhui ^b   Kadler, Karl E ^b  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

C proteinase; Electron microscopy; Endoplasmic reticulum; Furin; N proteinase; trans Golgi network (TGN)

Indexed keywords

BREFELDIN A; COLLAGEN; PROCOLLAGEN; PROCOLLAGEN C PROTEINASE; PROCOLLAGEN N PROTEINASE; PROCOLLAGEN TYPE 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; ENZYME ACTIVITY; FIBROBLAST; GOLGI COMPLEX; METATARSAL BONE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN SECRETION; PROTEIN TRANSPORT; RAT; SECRETORY PATHWAY; TENDON; TRANSMISSION ELECTRON MICROSCOPY;

AMINO ACID CHLOROMETHYL KETONES; ANIMALS; BONE MORPHOGENETIC PROTEIN 1; BREFELDIN A; CHICK EMBRYO; COLLAGEN; COLLAGEN TYPE I; ENZYME ACTIVATION; FIBROBLASTS; MICE; PROCOLLAGEN N-ENDOPEPTIDASE; RATS; SECRETORY PATHWAY; TENDONS; TRANS-GOLGI NETWORK;

RATTUS; VERTEBRATA;

EID: 84555189127     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20111379     Document Type: Article

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