Platinum(II) phenanthroimidazoles for targeting telomeric G-quadruplexes

ChemMedChem

Volumn 7, Issue 1, 2012, Pages 85-94

  Castor, Katherine J ^a   Mancini, Johanna ^b   Fakhoury, Johans ^a   Weill, Nathanael ^a   Kieltyka, Roxanne ^a   Englebienne, Pablo ^a   Avakyan, Nicole ^a   Mittermaier, Anthony ^a   Autexier, Chantal ^b   Moitessier, Nicolas ^a   Sleiman, Hanadi F ^a  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

Antitumor agents; G quadruplexes; Human telomeres; Phenanthroimidazole; Platinum

Indexed keywords

4 CHLOROPHENYLPHENANTHROIMIDAZOLE ETHYLENEDIAMINE PLATINUM; ANTINEOPLASTIC AGENT; BIPYRIDINE ETHYLENEDIAMINE PLATINUM; GUANINE QUADRUPLEX; NAPHTHYLPHENANTHROIMIDAZOLE ETHYLENEDIAMINE PLATINUM; PHENANTHROIMIDAZOLE PLATINUM; PHENYLPHENANTHROIMIDAZOLE ETHYLENEDIAMINE PLATINUM; PLATINUM; QUINOLINYLPHENANTHROIMIDAZOLE ETHYLENEDIAMINE PLATINUM; SALICYLPHENANTHROIMIDAZOLE ETHYLENEDIAMINE PLATINUM; TELOMERIC REPEAT BINDING FACTOR 2; UNCLASSIFIED DRUG;

ARTICLE; CIRCULAR DICHROISM; DNA SEQUENCE; DRUG STABILITY; FLUORESCENCE ANALYSIS; FLUORESCENCE INTERCALATOR DISPLACEMENT ASSAY; HUMAN; HUMAN CELL; HYDROGEN BOND; MOLECULAR MODEL; PRIORITY JOURNAL; TELOMERE; TELOMERIC REPEAT AMPLIFICATION PROTOCOL;

ANTINEOPLASTIC AGENTS; BASE SEQUENCE; CELL LINE; CELL LINE, TUMOR; CIRCULAR DICHROISM; DNA; G-QUADRUPLEXES; HUMANS; MODELS, MOLECULAR; NEOPLASMS; ORGANOPLATINUM COMPOUNDS; PHENANTHRENES; TELOMERE;

EID: 84555186713     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.201100453     Document Type: Article

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