Explaining statin inhibition effectiveness of HMG-CoA reductase by quantum biochemistry computations

Physical Chemistry Chemical Physics

Volumn 14, Issue 4, 2012, Pages 1389-1398

  Da Costa, Roner F ^a   Freire, Valder N ^a   Bezerra, Eveline M ^a   Cavada, Benildo S ^a   Caetano, Ewerton W S ^b   De Lima Filho, José L ^c   Albuquerque, Eudenilson L ^d  

^a FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

^b INSTITUTO FEDERAL DE EDUCAÇÃO   (Brazil)

^c FEDERAL UNIVERSITY OF PERNAMBUCO   (Brazil)

^d FEDERAL UNIVERSITY OF RIO GRANDE DO NORTE   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR;

ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; ENZYMOLOGY; HUMAN; HYPERCHOLESTEROLEMIA; METABOLISM; MOLECULAR DYNAMICS; THERMODYNAMICS;

BINDING SITES; HUMANS; HYDROXYMETHYLGLUTARYL COA REDUCTASES; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; HYPERCHOLESTEROLEMIA; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; THERMODYNAMICS;

EID: 84555179043     PISSN: 14639076     EISSN: None     Source Type: Journal    
DOI: 10.1039/c1cp22824b     Document Type: Article

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