Higher degrees of recanalization after mechanical thrombectomy for acute stroke are associated with improved outcome and decreased mortality: Pooled analysis of the MERCI and multi MERCI trials

American Journal of Neuroradiology

Volumn 32, Issue 11, 2011, Pages 2170-2174

  Fields, Jeremy D ^a   Lutsep, H L ^a   Smith, W S ^b  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTERY OCCLUSION; ARTICLE; DISEASE SEVERITY; FEMALE; GENERAL CONDITION IMPROVEMENT; HUMAN; MAJOR CLINICAL STUDY; MALE; MECHANICAL THROMBECTOMY; MORTALITY; OUTCOME ASSESSMENT; RECANALIZATION; RISK FACTOR; STROKE; STROKE PATIENT; TREATMENT OUTCOME;

ADULT; AGED; AGED, 80 AND OVER; CALIFORNIA; CEREBRAL REVASCULARIZATION; FEMALE; HUMANS; MALE; MIDDLE AGED; PREVALENCE; PROGNOSIS; RISK ASSESSMENT; RISK FACTORS; STROKE; SURVIVAL ANALYSIS; SURVIVAL RATE; THROMBECTOMY; TREATMENT OUTCOME;

EID: 84455188276     PISSN: 01956108     EISSN: 1936959X     Source Type: Journal    
DOI: 10.3174/ajnr.A2709     Document Type: Article

References (23)

1. Zangerle A, Kiechl S, Spiegel M, et al. Recanalization after thrombolysis in stroke patients: predictors and prognostic implications. Neurology 2007;68:39-44 (Pubitemid 46058549)
2. Wunderlich MT, Goertler M, Postert T, et al. Recanalization after intravenous thrombolysis: does a recanalization time window exist? Neurology 2007;68:1364-68 (Pubitemid 46659087)
3. Brekenfeld C, Remonda L, Nedeltchev K, et al. Endovascular neuroradiological treatment of acute ischemic stroke: techniques and results in 350 patients. Neurol Res 2005;27(suppl 1):S29-35 (Pubitemid 41510926)
4. Fields JD, Lindsay K, Liu KC, et al. Mechanical thrombectomy for the treatment of acute ischemic stroke. Expert Rev Cardiovasc Ther 2010;8:581-92
5. Rha JH, Saver JL. The impact of recanalization on ischemic stroke outcome: a meta-analysis. Stroke 2007;38:967-73 (Pubitemid 46568460)
6. Saqqur M, Uchino K, Demchuk AM, et al. Site of arterial occlusion identified by transcranial Doppler predicts the response to intravenous thrombolysis for stroke. Stroke 2007;38:948-54 (Pubitemid 46568457)
7. Arnold M, Nedeltchev K, Remonda L, et al. Recanalisation of middle cerebral artery occlusion after intra-arterial thrombolysis: different recanalisation grading systems and clinical functional outcome. J Neurol Neurosurg Psychiatry 2005;76:1373-76 (Pubitemid 41360974)
8. Zaidat OO, Suarez JI, Sunshine JL, et al. Thrombolytic therapy of acute ischemic stroke: correlation of angiographic recanalization with clinical outcome. AJNR Am J Neuroradiol 2005;26:880-84 (Pubitemid 43079785)
9. Stead LG, Gilmore RM, Bellolio MF, et al. Percutaneous clot removal devices in acute ischemic stroke: a systematic review and meta-analysis. Arch Neurol 2008;65:1024-30
10. Smith WS, Sung G, Starkman S, et al. Safety and efficacy of mechanical embolectomy in acute ischemic stroke: results of the MERCI trial. Stroke 2005;36:1432-38 (Pubitemid 40967507)
11. Smith WS, Sung G, Saver J, et al. Mechanical thrombectomy for acute ischemic stroke: final results of the Multi MERCI trial. Stroke 2008;39:1205-12 (Pubitemid 351440692)
12. Dohmen C, Bosche B, Graf R, et al. Identification and clinical impact of impaired cerebrovascular autoregulation in patients with malignant middle cerebral artery infarction. Stroke 2007;38:56-61 (Pubitemid 46035606)
13. Shin HK, Nishimura M, Jones PB, et al. Mild induced hypertension improves blood flow and oxygen metabolism in transient focal cerebral ischemia. Stroke 2008;39:1548-55
14. Soares BP, Chien JD, Wintermark M. MR and CT monitoring of recanalization, reperfusion, and penumbra salvage: everything that recanalizes does not necessarily reperfuse! Stroke 2009;40:S24-27
15. Alexandrov AV, Grotta JC. Arterial reocclusion in stroke patients treated with intravenous tissue plasminogen activator. Neurology 2002;59:862-67
16. Janjua N, Alkawi A, Suri MF, et al. Impact of arterial reocclusion and distal fragmentation during thrombolysis among patients with acute ischemic stroke. AJNR Am J Neuroradiol 2008;29:253-58 (Pubitemid 351287876)
17. Saqqur M, Molina CA, Salam A, et al. Clinical deterioration after intravenous recombinant tissue plasminogen activator treatment: a multicenter transcranial Doppler study. Stroke 2007;38:69-74 (Pubitemid 46035608)
18. Jovin TG, Gupta R, Horowitz MB, et al. Pretreatment ipsilateral regional cortical blood flow influences vessel recanalization in intra-arterial thrombolysis for MCA occlusion. AJNR Am J Neuroradiol 2007;28:164-67 (Pubitemid 46147559)
19. Nogueira RG, Liebeskind DS, Sung G, et al. Predictors of good clinical outcomes, mortality, and successful revascularization in patients with acute ischemic stroke undergoing thrombectomy: pooled analysis of the Mechanical Embolus Removal in Cerebral Ischemia (MERCI) and Multi MERCI Trials. Stroke 2009;40:3777-83
20. Lees KR, Bluhmki E, von Kummer R, et al. Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials. Lancet 2010;375:1695-703
21. Khatri P, Abruzzo T, Yeatts SD, et al. Good clinical outcome after ischemic stroke with successful revascularization is time-dependent. Neurology 2009;73:1066-72
22. Loh Y, Jahan R, McArthur DL, et al. Recanalization rates decrease with increasing thrombectomy attempts. AJNR Am J Neuroradiol 2010;31:935-39. Epub 2010 Jan 14
23. Tomsick T. TIMI, TIBI, TICI: I came, I saw, I got confused. AJNR Am J Neuroradiol 2007;28:382-84