Ultra-performance liquid chromatography-tandem mass spectrometry method for the determination of nitrendipine in dog plasma and its application to a pharmacokinetic study of a solid self-emulsifying pellet formulation

Arzneimittel-Forschung/Drug Research

Volumn 61, Issue 12, 2011, Pages 674-680

  Liu, Yanhua ^a,b   Wang, Zhiyuan ^a   Sun, Jin ^a   Wang, Yongjun ^a   He, Zhonggui ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b NINGXIA MEDICAL UNIVERSITY   (China)

Author keywords

Liquid liquid extraction; Nitrendipine; Pharmacokinetic study; Solid self emulsifying pellets; UPLC MS MS

Indexed keywords

CAS 39562 70 4; NITRENDIPINE; PROPRANOLOL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG FORMULATION; DRUG STABILITY; ELECTROSPRAY; EXPERIMENTAL DOG; LIMIT OF DETECTION; LIMIT OF QUANTITATION; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PLASMA CONCENTRATION-TIME CURVE; SINGLE DRUG DOSE; SOLID SELF EMULSIFYING PELLET FORMULATION; TANDEM MASS SPECTROMETRY; TIME TO MAXIMUM PLASMA CONCENTRATION; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

EID: 84455180513     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0031-1300586     Document Type: Article

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