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Volumn 6, Issue 12, 2011, Pages

Pathway-Based analysis of a Melanoma Genome-Wide association study: Analysis of genes related to Tumour-Immunosuppression

(201)  Schoof, Nils a,b   Iles, Mark M a,c   Bishop, D Timothy a,c   Newton Bishop, Julia A a,c   Barrett, Jennifer H a,c   Mann, Graham J c   Hopper, John L c   Aitken, Joanne F c   Armstrong, Bruce K c   Giles, Graham G c   Kefford, Richard F c   Cust, Anne c   Jenkins, Mark c   Aguilera, Paula c   Badenas, Celia c   Carrera, Cristina c   Cuellar, Francisco c   Gabriel, Daniel c   Martinez, Estefania c   Gonzalez, Melinda c   more..


Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BTLA GENE; BTNL2 GENE; CANCER SUSCEPTIBILITY; CBLB GENE; CCL17 GENE; CD160 GENE; CD274 GENE; CD28 GENE; CD40 GENE; CD40LG GENE; CD80 GENE; CD86 GENE; DENDRITIC CELL; DGKA GENE; FOXP3 GENE; GENE; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; ICOSLG GENE; IDO1 GENE; IL10 GENE; IL10RA GENE; IL10RB GENE; IL12A GENE; IL12B GENE; IL12RB1 GENE; IL17A GENE; IL17RA GENE; IL17RB GENE; IMMUNE DEFICIENCY; ITCH GENE; LGALS1 GENE; LGALS3 GENE; LILRB2 GENE; LILRB4 GENE; MELANOMA; PDCD1 GENE; RNF128 GENE; SINGLE NUCLEOTIDE POLYMORPHISM; TGFB1 GENE; TGFB2 GENE; TGFBR1 GENE; TGFBR2 GENE; TGFBR3 GENE; TNFRSF18 GENE; TREML2 GENE; VDR GENE; GENETIC PREDISPOSITION; GENETICS; IMMUNOLOGY; IMMUNOSUPPRESSIVE TREATMENT;

EID: 84455172956     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0029451     Document Type: Article
Times cited : (18)

References (46)
  • 1
    • 0033516179 scopus 로고    scopus 로고
    • Can skin cancers be minimized or prevented in organ transplant patients?
    • McCann J, (1999) Can skin cancers be minimized or prevented in organ transplant patients? J Natl Cancer Inst 91: 911-3.
    • (1999) J Natl Cancer Inst , vol.91 , pp. 911-913
    • McCann, J.1
  • 3
    • 0017096667 scopus 로고
    • Spontaneous regression of malignant melanoma: a review of the literature on incidence, clinical features, and possible mechanisms
    • Nathanson L, (1976) Spontaneous regression of malignant melanoma: a review of the literature on incidence, clinical features, and possible mechanisms. Natl Cancer Inst Monogr 44: 67-76.
    • (1976) Natl Cancer Inst Monogr , vol.44 , pp. 67-76
    • Nathanson, L.1
  • 4
    • 66749185326 scopus 로고    scopus 로고
    • Sun exposure and melanoma risk at different latitudes: a pooled analysis of 5700 cases and 7216 controls
    • Chang Y, Barrett J, Bishop D, Armstrong B, Bataille V, et al. (2009) Sun exposure and melanoma risk at different latitudes: a pooled analysis of 5700 cases and 7216 controls. International journal of epidemiology 38: 814-30.
    • (2009) International Journal of Epidemiology , vol.38 , pp. 814-830
    • Chang, Y.1    Barrett, J.2    Bishop, D.3    Armstrong, B.4    Bataille, V.5
  • 5
    • 0029903307 scopus 로고    scopus 로고
    • Enhanced growth of murine melanoma in ultraviolet-irradiated skin is associated with local inhibition of immune effector mechanisms
    • Donawho C, Muller H, Bucana C, Kripke M, (1996) Enhanced growth of murine melanoma in ultraviolet-irradiated skin is associated with local inhibition of immune effector mechanisms. The Journal of Immunology 157: 781.
    • (1996) The Journal of Immunology , vol.157 , pp. 781
    • Donawho, C.1    Muller, H.2    Bucana, C.3    Kripke, M.4
  • 6
  • 7
    • 65249146092 scopus 로고    scopus 로고
    • Tolerogenic dendritic cells in cancer, transplantation, and autoimmune diseases
    • Suciu-Foca N, Berloco P, Cortesini R, (2009) Tolerogenic dendritic cells in cancer, transplantation, and autoimmune diseases. Human immunology 70: 277-80.
    • (2009) Human Immunology , vol.70 , pp. 277-280
    • Suciu-Foca, N.1    Berloco, P.2    Cortesini, R.3
  • 11
    • 0028025028 scopus 로고
    • Defective lymphokine production by most cd8+ and cd4+ tumor-specific t cell clones derived from human melanoma-infiltrating lymphocytes in response to autologous tumor cells in vitro
    • Guilloux Y, Viret C, Gervois N, Le Drean E, Pandolfino MC, et al. (1994) Defective lymphokine production by most cd8+ and cd4+ tumor-specific t cell clones derived from human melanoma-infiltrating lymphocytes in response to autologous tumor cells in vitro. Eur J Immunol 24: 1966-73.
    • (1994) Eur J Immunol , vol.24 , pp. 1966-1973
    • Guilloux, Y.1    Viret, C.2    Gervois, N.3    Le Drean, E.4    Pandolfino, M.C.5
  • 12
    • 33645286546 scopus 로고    scopus 로고
    • Regulatory t cells, tumour immunity and immunotherapy
    • Zou W, (2006) Regulatory t cells, tumour immunity and immunotherapy. Nat Rev Immunol 6: 295-307.
    • (2006) Nat Rev Immunol , vol.6 , pp. 295-307
    • Zou, W.1
  • 13
    • 65949111746 scopus 로고    scopus 로고
    • Foxp3 defines regulatory t cells in human tumor and autoimmune disease
    • Kryczek I, Liu R, Wang G, Wu K, Shu X, et al. (2009) Foxp3 defines regulatory t cells in human tumor and autoimmune disease. Cancer Res 69: 3995-4000.
    • (2009) Cancer Res , vol.69 , pp. 3995-4000
    • Kryczek, I.1    Liu, R.2    Wang, G.3    Wu, K.4    Shu, X.5
  • 14
    • 34547896612 scopus 로고    scopus 로고
    • Evaluation of tumour-infiltrating cd4+ cd25+ foxp3+ regulatory t cells in human cutaneous benign and atypical naevi, melanomas and melanoma metastases
    • Mourmouras V, Fimiani M, Rubegni P, Epistolato M, Malagnino V, et al. (2007) Evaluation of tumour-infiltrating cd4+ cd25+ foxp3+ regulatory t cells in human cutaneous benign and atypical naevi, melanomas and melanoma metastases. British Journal of Dermatology 157: 531-539.
    • (2007) British Journal of Dermatology , vol.157 , pp. 531-539
    • Mourmouras, V.1    Fimiani, M.2    Rubegni, P.3    Epistolato, M.4    Malagnino, V.5
  • 15
    • 75749151759 scopus 로고    scopus 로고
    • Novel immunotherapies as potential therapeutic partners for traditional or targeted agents: cytotoxic t-lymphocyte antigen-4 blockade in advanced melanoma
    • Agarwala S, (2010) Novel immunotherapies as potential therapeutic partners for traditional or targeted agents: cytotoxic t-lymphocyte antigen-4 blockade in advanced melanoma. Melanoma Research 20: 1.
    • (2010) Melanoma Research , vol.20 , pp. 1
    • Agarwala, S.1
  • 16
    • 34848819211 scopus 로고    scopus 로고
    • Failure at the effector phase: immune barriers at the level of the melanoma tumor microenvironment
    • Gajewski TF, (2007) Failure at the effector phase: immune barriers at the level of the melanoma tumor microenvironment. Clin Cancer Res 13: 5256-61.
    • (2007) Clin Cancer Res , vol.13 , pp. 5256-5261
    • Gajewski, T.F.1
  • 17
    • 71849109946 scopus 로고    scopus 로고
    • Polymorphisms in the cd28/ctla4/icos genes: role in malignant melanoma susceptibility and prognosis?
    • Bouwhuis MG, Gast A, Figl A, Eggermont AM, Hemminki K, et al. (2009) Polymorphisms in the cd28/ctla4/icos genes: role in malignant melanoma susceptibility and prognosis? Cancer Immunol Immunother 59: 303-312.
    • (2009) Cancer Immunol Immunother , vol.59 , pp. 303-312
    • Bouwhuis, M.G.1    Gast, A.2    Figl, A.3    Eggermont, A.M.4    Hemminki, K.5
  • 19
    • 0346880454 scopus 로고    scopus 로고
    • Cytokine gene single nucleotide polymorphisms and susceptibility to and prognosis in cutaneous malignant melanoma
    • Howell WM, Turner SJ, Theaker JM, Bateman AC, (2003) Cytokine gene single nucleotide polymorphisms and susceptibility to and prognosis in cutaneous malignant melanoma. Eur J Immunogenet 30: 409-14.
    • (2003) Eur J Immunogenet , vol.30 , pp. 409-414
    • Howell, W.M.1    Turner, S.J.2    Theaker, J.M.3    Bateman, A.C.4
  • 20
    • 69949165787 scopus 로고    scopus 로고
    • Distal and proximal interleukin (il)-10 promoter polymorphisms associated with risk of cutaneous melanoma development: a case- control study
    • Schoof N, Von Bonin F, König I, Mössner R, Krüger U, et al. (2009) Distal and proximal interleukin (il)-10 promoter polymorphisms associated with risk of cutaneous melanoma development: a case- control study. Genes and immunity 10: 586-590.
    • (2009) Genes and Immunity , vol.10 , pp. 586-590
    • Schoof, N.1    Von Bonin, F.2    König, I.3    Mössner, R.4    Krüger, U.5
  • 21
    • 68149179663 scopus 로고    scopus 로고
    • Genome-wide association study identifies three loci associated with melanoma risk
    • Bishop DT, Demenais F, Iles MM, Harland M, Taylor JC, et al. (2009) Genome-wide association study identifies three loci associated with melanoma risk. Nat Genet 41: 920-5.
    • (2009) Nat Genet , vol.41 , pp. 920-925
    • Bishop, D.T.1    Demenais, F.2    Iles, M.M.3    Harland, M.4    Taylor, J.C.5
  • 22
    • 58149253310 scopus 로고    scopus 로고
    • On the utility of gene set methods in genomewide association studies of quantitative traits
    • Chasman DI, (2008) On the utility of gene set methods in genomewide association studies of quantitative traits. Genet Epidemiol 32: 658-68.
    • (2008) Genet Epidemiol , vol.32 , pp. 658-668
    • Chasman, D.I.1
  • 23
    • 65949104586 scopus 로고    scopus 로고
    • Genomewide association studies and human disease
    • Hardy J, Singleton A, (2009) Genomewide association studies and human disease. N Engl J Med 360: 1759-68.
    • (2009) N Engl J Med , vol.360 , pp. 1759-1768
    • Hardy, J.1    Singleton, A.2
  • 24
    • 77449140764 scopus 로고    scopus 로고
    • Gene and pathway-based second-wave analysis of genome-wide association studies
    • Peng G, Luo L, Siu H, Zhu Y, Hu P, et al. (2010) Gene and pathway-based second-wave analysis of genome-wide association studies. Eur J Hum Genet 18: 111-7.
    • (2010) Eur J Hum Genet , vol.18 , pp. 111-117
    • Peng, G.1    Luo, L.2    Siu, H.3    Zhu, Y.4    Hu, P.5
  • 25
    • 36249029788 scopus 로고    scopus 로고
    • Pathway-based approaches for analysis of genomewide association studies
    • Wang K, Li M, Bucan M, (2007) Pathway-based approaches for analysis of genomewide association studies. Am J Hum Genet 81.
    • (2007) Am J Hum Genet , vol.81
    • Wang, K.1    Li, M.2    Bucan, M.3
  • 26
    • 77951210494 scopus 로고    scopus 로고
    • Pathway analysis of GWAs provides new insights into genetic susceptibility to 3 inflammatory diseases
    • Eleftherohorinou H, Wright V, Hoggart C, Hartikainen AL, Jarvelin MR, et al. (2009) Pathway analysis of GWAs provides new insights into genetic susceptibility to 3 inflammatory diseases. PLoS One 4: e8068.
    • (2009) PLoS One , vol.4
    • Eleftherohorinou, H.1    Wright, V.2    Hoggart, C.3    Hartikainen, A.L.4    Jarvelin, M.R.5
  • 27
    • 67649584052 scopus 로고    scopus 로고
    • Gene ontology analysis of GWA study data sets provides insights into the biology of bipolar disorder
    • Holmans P, Green EK, Pahwa JS, Ferreira MA, Purcell SM, et al. (2009) Gene ontology analysis of GWA study data sets provides insights into the biology of bipolar disorder. Am J Hum Genet 85: 13-24.
    • (2009) Am J Hum Genet , vol.85 , pp. 13-24
    • Holmans, P.1    Green, E.K.2    Pahwa, J.S.3    Ferreira, M.A.4    Purcell, S.M.5
  • 29
    • 53649098737 scopus 로고    scopus 로고
    • Pathway analysis of seven common diseases assessed by genome-wide association
    • Torkamani A, Topol EJ, Schork NJ, (2008) Pathway analysis of seven common diseases assessed by genome-wide association. Genomics 92: 265-72.
    • (2008) Genomics , vol.92 , pp. 265-272
    • Torkamani, A.1    Topol, E.J.2    Schork, N.J.3
  • 30
    • 61549115034 scopus 로고    scopus 로고
    • Diverse genome-wide association studies associate the il12/il23 pathway with crohn disease
    • Wang K, Zhang H, Kugathasan S, Annese V, Bradfield JP, et al. (2009) Diverse genome-wide association studies associate the il12/il23 pathway with crohn disease. Am J Hum Genet 84: 399-405.
    • (2009) Am J Hum Genet , vol.84 , pp. 399-405
    • Wang, K.1    Zhang, H.2    Kugathasan, S.3    Annese, V.4    Bradfield, J.P.5
  • 31
    • 77953151341 scopus 로고    scopus 로고
    • Pathway analysis of breast cancer genome-wide association study highlights three pathways and one canonical signaling cascade
    • Menashe I, Maeder D, Garcia-Closas M, Figueroa J, Bhattacharjee S, et al. (2010) Pathway analysis of breast cancer genome-wide association study highlights three pathways and one canonical signaling cascade. Cancer Research 70: 4453.
    • (2010) Cancer Research , vol.70 , pp. 4453
    • Menashe, I.1    Maeder, D.2    Garcia-Closas, M.3    Figueroa, J.4    Bhattacharjee, S.5
  • 32
    • 71249124573 scopus 로고    scopus 로고
    • Comparing gene set analysis methods on single-nucleotide polymorphism data from genetic analysis workshop 16
    • Tintle NL, Borchers B, Brown M, Bekmetjev A, (2009) Comparing gene set analysis methods on single-nucleotide polymorphism data from genetic analysis workshop 16. BMC Proc 3 (Suppl 7): S96.
    • (2009) BMC Proc , vol.3 , Issue.SUPPL. 7
    • Tintle, N.L.1    Borchers, B.2    Brown, M.3    Bekmetjev, A.4
  • 33
    • 34548292504 scopus 로고    scopus 로고
    • Plink: a tool set for whole-genome association and population-based linkage analyses
    • Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MA, et al. (2007) Plink: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 81: 559-575.
    • (2007) Am J Hum Genet , vol.81 , pp. 559-575
    • Purcell, S.1    Neale, B.2    Todd-Brown, K.3    Thomas, L.4    Ferreira, M.A.5
  • 34
    • 68049098168 scopus 로고    scopus 로고
    • R: A Language and Environment for Statistical Computing
    • R Development Core Team, Available: URL. ISBN 3-900051-07-0. (Accessed 2011 Dec 2.)
    • R Development Core Team (2009) R: A Language and Environment for Statistical Computing. R Foundation for Statistical Computing, Vienna, Austria. Available: URL http://www.R-project.org. ISBN 3-900051-07-0. (Accessed 2011 Dec 2.).
    • (2009) R Foundation for Statistical Computing, Vienna, Austria
  • 35
  • 36
    • 27344435774 scopus 로고    scopus 로고
    • Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles
    • Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, et al. (2005) Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci U S A 102: 15545-50.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 15545-15550
    • Subramanian, A.1    Tamayo, P.2    Mootha, V.K.3    Mukherjee, S.4    Ebert, B.L.5
  • 37
    • 35348890683 scopus 로고    scopus 로고
    • On testing the significance of sets of genes
    • Efron B, Tibshirani R, (2007) On testing the significance of sets of genes. Ann Appl Stat 1: 107-129.
    • (2007) Ann Appl Stat , vol.1 , pp. 107-129
    • Efron, B.1    Tibshirani, R.2
  • 38
    • 77954300600 scopus 로고    scopus 로고
    • Gsa-snp: a general approach for gene set analysis of polymorphisms
    • Nam D, Kim J, Kim S, Kim S, (2010) Gsa-snp: a general approach for gene set analysis of polymorphisms. Nucleic Acids Research 38 (Suppl): W749-54.
    • (2010) Nucleic Acids Research , vol.38 , Issue.SUPPL.
    • Nam, D.1    Kim, J.2    Kim, S.3    Kim, S.4
  • 39
    • 77953123145 scopus 로고    scopus 로고
    • Insights into colon cancer etiology via a regularized approach to gene set analysis of GWAS data
    • Chen L, Hutter C, Potter J, Liu Y, Prentice R, et al. (2010) Insights into colon cancer etiology via a regularized approach to gene set analysis of GWAS data. The American Journal of Human Genetics 86: 860-871.
    • (2010) The American Journal of Human Genetics , vol.86 , pp. 860-871
    • Chen, L.1    Hutter, C.2    Potter, J.3    Liu, Y.4    Prentice, R.5
  • 40
    • 5044220930 scopus 로고    scopus 로고
    • Ido expression by dendritic cells: tolerance and tryptophan catabolism
    • Mellor A, Munn D, (2004) Ido expression by dendritic cells: tolerance and tryptophan catabolism. Nature Reviews Immunology 4: 762-774.
    • (2004) Nature Reviews Immunology , vol.4 , pp. 762-774
    • Mellor, A.1    Munn, D.2
  • 43
    • 11144241063 scopus 로고    scopus 로고
    • Galectins as modulators of tumour progression
    • Liu F, Rabinovich G, (2005) Galectins as modulators of tumour progression. Nature Reviews Cancer 5: 29-41.
    • (2005) Nature Reviews Cancer , vol.5 , pp. 29-41
    • Liu, F.1    Rabinovich, G.2
  • 45
    • 73349088135 scopus 로고    scopus 로고
    • Evaluation of the prognostic significance of serum galectin-3 in American joint committee on cancer stage iii and stage iv melanoma patients
    • Vereecken P, Awada A, Suciu S, Castro G, Morandini R, et al. (2009) Evaluation of the prognostic significance of serum galectin-3 in American joint committee on cancer stage iii and stage iv melanoma patients. Melanoma Research 19: 316.
    • (2009) Melanoma Research , vol.19 , pp. 316
    • Vereecken, P.1    Awada, A.2    Suciu, S.3    Castro, G.4    Morandini, R.5
  • 46
    • 0036372440 scopus 로고    scopus 로고
    • Transforming growth factor-β in t-cell biology
    • Gorelik L, Flavell R, (2002) Transforming growth factor-β in t-cell biology. Nature Reviews Immunology 2: 46-53.
    • (2002) Nature Reviews Immunology , vol.2 , pp. 46-53
    • Gorelik, L.1    Flavell, R.2


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