Lighting for the human circadian clock: Recent research indicates that lighting has become a public health issue

Medical Hypotheses

Volumn 63, Issue 4, 2004, Pages 588-596

  Pauley, Stephen M ^a  

^a PO Box 3759 ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MELATONIN;

BLUE LIGHT; BREAST CANCER; CANCER GROWTH; CIRCADIAN RHYTHM; COLORECTAL CANCER; EVOLUTION; HEALTH HAZARD; HUMAN; ILLUMINATION; LIGHT; LIPID DIET; MEDICAL RESEARCH; NONHUMAN; NURSING HOME; PRIORITY JOURNAL; RETINA GANGLION CELL; REVIEW; SHIFT WORKER; TUMOR GROWTH;

ANIMALIA; MINK CELL FOCUS-FORMING VIRUS; RATTUS NORVEGICUS; VERTEBRATA;

EID: 8444253636     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mehy.2004.03.020     Document Type: Article

References (79)

1. Anisimov V.N., Hansen J. Light, endocrine systems and cancer - a meeting report. Neuroendocrinol. Lett. 23(Suppl 2):2002;84-87
2. Anisimov V.N., Popovich I.G., Zabezhinski M.A. Melatonin and colon carcinogenesis. I. Inhibitory effect of melatonin on development of intestinal tumors induced by 1,2-dimethylhydrazine in rats. Carcinogenesis. 18:1997;1549-1553
3. Anisimov V.N., Popovich I.G., Shtylik A.V., Zabezinski M.A., Fen-Huh., Gurevich H., et al. Melatonin and colon carcinogenesis. III. Effect of melatonin on proliferative activity and apoptosis in colon mucosa and colon tumors induced by 1,2-dimethylhydrazine in rats. Exp. Toxicol. Pathol. 52:2000;71-76
4. Appell D. The new uncertainty principle. 2001;Scientific American
5. Arendt J. Melatonin, circadian rhythms, and sleep. New Engl. J. Med. 343(15):2000;1114-1116
6. Berson D.M. Strange vision: ganglion cells as circadian photoreceptors. Trends Neurosci. 26(6):2003;314-320
7. Berson D.M., Dunn F.A., Motoharu T. Phototransduction by retinal ganglion cells that set the circadian clock. Science. 295:2002;1070-1073
8. Berson DM. Melanopsin and phototransduction by retinal ganglion cells. In: Final Report. The Fifth International LRO Lighting Research Symposium, Light and Human Health, November 3-5, 2002. Report No. 1009370. Palo Alto, CA: The Electric Power Research Institute; 2004
9. Blask D.E., Dauchy R.T., Sauer L.A., Krause J.A., Brainard G.C. Growth and fatty acid metabolism of human breast cancer (MCF-7) xenografts in nude rats: impact of constant light-induced nocturnal melatonin suppression. Breast Cancer Res. Tr. 79(3):2003;313-320
10. Blask D.E., Sauer L.A., Dauchy R.T., Holowachuk E.W., Ruhoff M.S., Kopff H.S. Melatonin inhibition of cancer growth in vivo involves suppression of tumor fatty acid metabolism via melatonin receptor-mediated signal transduction events. Cancer Res. 59:1999;4693-4701
11. Blask D.E., Dauchy R.T., Sauer L.A., Krause J.A., Brainard G.C. Light during darkness, melatonin suppression and cancer progression. Neuroendocrinol. Lett. 23(Suppl 2):2002;52-56
12. Blask DE, Wilson ST, Cos S, Lemus-Wilson AM, Liaw L. Pineal and circadian influence on the inhibitory growth response of experimental breast cancer to melatonin. In: Proceedings of the 74th Annual Meeting of Endocrinology Society; 1992. p. 376
13. Blask D.E., Sauer L.A., Dauchy R.T. Melatonin as a chronobiotic/ anticancer agent: cellular, biochemical, and molecular mechanisms of action and their implications for circadian-based cancer therapy. Curr. Top. Med. Chem. 2(2):2002;113-132
14. Brainard GC. Photoreception for regulation of melatonin and the circadian system in humans. In: Final Report. The Fifth International LRO Lighting Research Symposium, Light and Human Health, November 3-5, 2002. Report No. 1009370. Palo Alto, CA: The Electric Power Research Institute; 2004
15. Brainard G.C., Richardson B.A., Petterborg L.J., Reiter R.J. The effect of different light intensities on pineal melatonin content. Brain Res. 233(1):1982;75-81
16. Brainard G.C., Hanifin J.P., Rollag M.D., Greeson J., Byrne B., Glickman G., et al. Human melatonin regulation is not mediated by the three cone photopic visual system. J. Clin. Endocrinol. Metab. 86(1):2001;433-436
17. Brainard G.C., Rollag M.D., Hanifin J.P. Photic regulation of melatonin in humans: ocular and neural signal transduction. J. Biol. Rhythm. 12(6):1997;537-546
18. Brainard G.C., Lewy A.J., Menaker M., Fredrickson R.H., Miller L.S., Weleber R.G., et al. Dose-response relationship between light irradiance and the suppression of plasma melatonin in human volunteers. Brain Res. 454(1-2):1988;212-218
19. Brainard G.C., Hanifin J.P., Greeson J.M., Byrne B., Glickman G., Gerner E., et al. Action spectrum for melatonin regulation in humans: evidence for a novel circadian photoreceptor. J. Neurosci. 21(16):2001;6405-6412
20. Brainard G.C. Pineal research: the decade of transformation. J. Neural Transm.-Suppl. (13):1978;3-10
21. Brainard G.C., Richardson B.A., King T.S., Reiter R.J. The influence of different light spectra on the suppression of pineal melatonin content in the Syrian hamster. Brain Res. 294(2):1984;333-339
22. Bubenik G.A., Blask D.E., Brown G.M., Maestroni G.J., Pang S.F., Reiter R.J., et al. Prospects of the clinical utilization of melatonin. Biol. Signal. Recept. 7(4):1998;195-219
23. Carlin S. The precautionary principle. Available from: 〈http://www.preventionisthecure.org/preprin.html〉. Web site for Devra Davs PhD
24. Coleman M.P., Reiter R.J. Breast cancer, blindness and melatonin. Eur. J. Cancer. 28(2-3):1992;501-503. Review
25. Cos S., Sanchez-Barcelo E.J. Melatonin and mammary pathological growth. Front. Neuroendocrinol. 21(2):2000;133-170
26. Cos S., Sanchez-Barcelo E.J. Melatonin, experimental basis for a possible application in breast cancer prevention and treatment. Histol. Histopathol. 15(2):2000;637-647. Review
27. Davis S., Mirick D.K., Stevens R.G. Night-shift work, light at night, and risk of breast cancer. J. Natl. Cancer Inst. 93:2001;1557-1562
28. Dillon D.C., Easley S.E., Asch B.B., Cheney R.T., Brydon L., Jockers R., et al. Differential expression of high-affinity melatonin receptors (MT1) in normal and malignant human breast tissue. Am. J. Clin. Pathol. 118:2002;451-458
29. Dollins A.B., Lynch H.J., Wurtman R.J., Deng M.H., Lieberman H.R. Effects of illumination on human nocturnal serum melatonin levels and performance. Physiol. Behav. 53(1):1993;153-160
30. Erren T.C. Does light cause internal cancers? The problem and challenge of an ubiquitous exposure. Neuroendocrinol. Lett. 23(Suppl 2):2002;61-70
31. Erren T.C., Piekarski C. Does winter darkness in the Artic protect against cancer? The melatonin hypothesis revisited. Med. Hypotheses. 53(1):1999;1-5
32. Erren T.C., Stevens R.G. Light, melatonin and internal cancers - recent facts and research perspectives. Gesundheitswesen. 64(5):2002;278-283. German
33. Falkson G., Falkson H.C., Steyn M.E., Rapoport B.L., Meyer B.J. Plasma melatonin in patients with breast cancer. Oncology. 47(5):1990;401-405
34. Ferriol M., Venereo Y., Orta X., Castellanos J.M., Segovia-Selvestre T. In vitro effects of melatonin on cell proliferation in a colon adenocarcinoma line. J. Appl. Toxicol. 20:2000;21-24
35. Feychting M., Osterlund B., Ahlbom A. Reduced cancer incidence among the blind. Epidemiology. 9(5):1998;490-494
36. Figueiro M, Eggleston G, Rea MS. Effects of light exposure on behavior of Alzheimer's patients-a pilot study. In: Final Report. The Fifth International LRO Lighting Research Symposium, Light and Human Health, November 3-5, 2002. Report No. 1009370. Palo Alto, CA: The Electric Power Research Institute; 2004
37. Fontoynont M. Simulation of sunlight in indoor environments. In: Final Report. The Fifth International LRO Lighting Research Symposium, Light and Human Health, November 3-5, 2002. Report No. 1009370. Palo Alto, CA: The Electric Power Research Institute; 2004
38. Glickman G., Levin R., Brainard G.C. Ocular input for human melatonin regulation: relevance to breast cancer. Neuroendocrinol. Lett. (Suppl 2):2002;17-22
39. Hahn R.A. Profound bilateral blindness and the incidence of breast cancer. Epidemiology. 2:1991;208-210
40. Hansen J. Light at night, shiftwork, and breast cancer risk. J. Natl, Cancer Inst. 93:2001;1513-1515. [editorial]
41. Hansen J. Increased breast cancer risk among women who work predominately at night. Epidemiology. 12:2001;74-77
42. Hattar S., Lucas R.J., Mrosovsky N., Thopson S., Douglas R.H., Hankins M.W., et al. Melanopsin and rod-cone photoreceptive systems account for all accessory major visual functions in mice. Nature. 424:2003;75-81
43. Hatonen T., Alila-Johansson A., Mustanoja S., Laakso M.L. Suppresson of melatonin by 2000-lx light in humans with closed eyes. Biol. Psychiat. 46:1999;827-831
44. Holick MF, Vitamin D: a required supplement or a sunshine hormone? In: Final Report. The Fifth International LRO Lighting Research Symposium, Light and Human Health, November 3-5, 2002. Report No. 1009370. Palo Alto, CA: The Electric Power Research Institute; 2004
45. Karbownik M., Lewinski A., Reiter R.J. Anticarcinogenic actions of melatonin which involve antioxidative processes: comparison with other antioxidants. Int. J. Biochem. Cell. Biol. 33(8):2001;735-753
46. Kliukiene J., Tynes T., Andersen A. Risk of breast cancer among Norwegian women with visual impairment. Br. J. Cancer. 84(3):2001;397-399
47. Lewy A.J., Wehr T.A., Goodwin F.K. Light suppresses melatonin secretions in humans. Science. 210:1980;1267-1269
48. Lockley S.W., Brainard G.C., Czeisler C.A. High sensitivity of the human circadian melatonin rhythm to resetting by short wavelength light. J. Clin. Endocrinol. Metab. 88(9):2003;4502-4505
49. Lucas R.J., Hattar S., Takao M., Berson D.M., Foster R.G., Yau K.W. Diminished pupillary light reflex at high irradiances in melanopsin knock out mice. Science. 2003;245-247
50. Miller N. Lighting for seniors: obstacles in applying the research. In: Final Report. The Fifth International LRO Lighting Research Symposium, Light and Human Health, November 3-5, 2002. Report No. 1009370. Palo Alto, CA: The Electric Power Research Institute; 2004
51. Montague P. The precautionary principle Rachel's environment and health weekly #586 February 19; 1998. Available from: 〈http://www.monitor.net/ rachel/r586.html〉
52. Nathan P.J., Burrows G.D., Norman T.R. The effect of dim light on suppression of nocturnal melatonin in healthy women and men. J. Neural. Transm. 104(6-7):1997;643-648. Curr Top Med Chem 2002;2(2):113-32
53. Noell-Waggoner E. Let there be light, or face the consequences: a national concern for our aging population. In: Final Report. The Fifth International LRO Lighting Research Symposium, Light and Human Health, November 3-5, 2002. Report No. 1009370. Palo Alto, CA: The Electric Power Research Institute; 2004
54. Pang S.F., Pang C.S., Poon A.M., Lee P.P., Liu Z.M., Shiu S.Y. Melatonin: a chemical photoperiodic signal with clinical significance in humans. Chin. Med. J. (Engl.). 111(3):1998;197-203
55. Pukkala E., Verkasalo P.K., Ojamo M., Rudanko S.L. Visual impairment and cancer: a population-based cohort study in Finland. Cancer Cause. Control. 10:1999;13-20
56. Quera-Salva M.A., Defrance R., Claustrat B., De Lattre J., Guilleminault C. Rapid shift in sleep time and acrophase of melatonin secretion in short shift work schedule. Sleep. 19(7):1996;539-543
57. Ramstad K., Loge J.H. Melatonin treatment of a blind child with serious sleep disorders. Tidsskr Nor Laegeforen. 122(10):2002;1005-1006. Norwegian
58. Rea MS. Light-much more than vision. keynote address. In: Final Report. The Fifth International LRO Lighting Research Symposium, Light and Human Health, November 3-5, 2002. Report No. 1009370. Palo Alto, CA: The Electric Power Research Institute; 2004
59. Rea M.S., Bullough J.D., Figueiro M.G. Phototransduction for human melatonin suppression. J. Pineal Res. 32(4):2002;209-213
60. Reiter RJ. Melatonin bantam books; 1995
61. Reiter R.J. Melatonin: clinical relevance. Best Pract. Res. Clin. Endocrinol. Metab. 17(2):2003;273-285
62. Reiter R.J., Tan D.X., Burkhardt S., Manchester L.C. Melatonin in plants. Nutr. Rev. 59(9):2001;286-290
63. Reiter R.J., Tan D., Cabrera J., D'Arpa D. Melatonin and tryptophan derivatives as free radical scavengers and antioxidants. Adv. Exp. Med. Biol. 467:1999;379-387
64. Roberts JE. Light interactions with the human eye as a function of age. In: Final Report. The Fifth International LRO Lighting Research Symposium, Light and Human Health, November 3-5, 2002. Report No. 1009370. Palo Alto, CA: The Electric Power Research Institute; 2004
65. Sauer L.A., Dauchy R.T., Blask D.E. Melatonin inhibits fatty acid transport in inguinal fat pads of hepatoma 7288CTC-bearing and normal Buffalo rats via receptor-mediated signal transduction. Life Sci. 68(25):2001;2835-2844
66. Sauer L.A., Dauchy R.T., Blask D.E. Polyunsaturated fatty acids, melatonin, and cancer prevention. Biochem. Pharmacol. 61:2001;1455-1462
67. Sauer L.A., Dauchy R.T., Blask D.E. Mechanism for the antitumor and anticachetic effects of. n-3 fatty acids Cancer Res. 60:2000;5289-9567
68. Sauer L.A., Dauchy R.T., Blask D.E., Armstrong B.J., Scalici S. 13-Hydroxyoctadecadienoic acid is the mitogenic signal for linoleic acid- dependent growth in rat hepatoma 7288CTC in vivo. Cancer Res. 59(18):1999;4688-4692
69. Schernhammer E.S., Schulmeister K. Melatonin and cancer risk: does light at night compromise physiologic cancer protection by lowering serum melatonin levels? Brit. J. Cancer. 90(5):2004;941-943
70. Schernhammer E.S., Laden F., Speizer F.E., Willett W.C., Hunter D.J., Kawachi I., et al. Rotating night shifts and risk of breast cancer in women participating in the Nurses' Health Study. J. Natl. Cancer Inst. 93:2001;1563-1568
71. Schernhammer E.S., Laden F., Speizer F.E., Willett W.C., Hunter D.J., Kawachi I., et al. Night-shift work and risk of colorectal cancer in the Nurses' Health Study. J. Natl. Cancer Inst. 95(11):2003;825-828
72. Schulmeister K, Weber M, Bogner W, Schernhammer E. Application of melatonin action spectra on practical lighting issues. In: Final Report. The Fifth International LRO Lighting Research Symposium, Light and Human Health, November 3-5, 2002. Report No. 1009370. Palo Alto, CA: The Electric Power Research Institute; 2004
73. Stevens R.G. Lighting during the day and night: possible impact on risk of breast cancer. Neuroendocrinol. Lett. 23(Suppl 2):2002;57-60
74. Stevens R.G., Rae M.S. Light in the built environment: potential role of circadian disruption in endocrine disruption and breast cancer. Cancer Cause. Control. 12:2001;279-287
75. Stevens RG. Epidemiological evidence on artificial lighting patterns and risk of breast cancer. Final Report. The Fifth International LRO Lighting Research Symposium, Light and Human Health, November 3-5, 2002. Report No. 1009370. Palo Alto, CA: The Electric Power Research Institute; 2004
76. Stewart K.T., Gaddy J.R., Byrne B., Miller S., Brainard G.C. Effects of green or white light for treatment of seasonal depression. Psychiat. Res. 38(3):1991;261-270
77. Veitch JA. Principles of healthy lighting. In: Final Report. The Fifth International LRO Lighting Research Symposium, Light and Human Health, November 3-5, 2002. Report No. 1009370. Palo Alto, CA: The Electric Power Research Institute; 2004
78. Verkasalo P.K., Pukkala E., Stevens R.G., Ojamo M., Rudanko S.L. Inverse association between breast cancer incidence and degree of visual impairment in Finland. Br. J. Cancer. 80(9):1999;1459-1460
79. Wiley T.S., Formby B. Lights out; sleep, sugar, and survival. 2000;Pocket Books