Supplementation and delivery of n-3 fatty acids through spray-dried milk reduce serum and liver lipids in rats

Lipids

Volumn 39, Issue 7, 2004, Pages 627-632

  Ramaprasad, T R ^a   Baskaran, V ^a   Sambaiah, K ^a   Lokesh, B R ^a  

^a CENTRAL FOOD TECHNOLOGICAL RESEARCH INSTITUTE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL ORGANS; BODY FLUIDS; DRYING; LIPIDS; LIVING SYSTEMS STUDIES; NUTRITION; OILS AND FATS; TISSUE;

CEREALS; DIETARY; LIVER LIPIDS; SPRAY DRYING;

FATTY ACIDS;

ARACHIS OIL; DOCOSAHEXAENOIC ACID; FATTY ACID; FISH OIL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; ICOSAPENTAENOIC ACID; LINOLEIC ACID; LINSEED OIL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; OMEGA 3 FATTY ACID; PHOSPHOLIPID; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIET SUPPLEMENTATION; DIETARY INTAKE; FOOD INTAKE; LIPID BRAIN LEVEL; LIPID LIVER LEVEL; MALE; MILK; NONHUMAN; ORGAN WEIGHT; PHOSPHOLIPID BLOOD LEVEL; RAT; TRIACYLGLYCEROL BLOOD LEVEL; WEIGHT GAIN;

ANIMALS; DIET; DIETARY FATS; DIETARY SUPPLEMENTS; FATTY ACIDS, OMEGA-3; FOOD, FORMULATED; HUMANS; INDIA; LIPIDS; LIVER; MALE; MILK; OILS; RATS; RATS, WISTAR;

ANIMALIA; ARACHIS; RATTUS NORVEGICUS;

EID: 8444220086     PISSN: 00244201     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11745-004-1275-6     Document Type: Article

References (43)

1. Simopoulos, A.P. (1999) Essential Fatty Acids in Health and Chronic Diseases, Am. J. Clin. Nutr. 70, S560-S569.
2. Ghafoorunissa (1990) Availability of Linoleic Acid from Cereal-Pulse Diets, Lipids 25, 763-766.
3. Ghafoorunissa (1996) Fats in Indian Diets and Their Nutritional Implications, Lipids 31, S287-S291.
4. Achaya, K.T. (1995) Fat Intake in India - An Update, J. Sci. Ind. Res. 54, 91-97.
5. Roche, H.M. (1999) Unsaturated Fatty Acids, Proc. Nutr. Soc. 58, 397-401.
6. Stanley, J. (2004) What is the Appropriate Balance Between Intakes of n-6 and n-3 PUFA in the Diet? Lipid Technol. 16, 61-63.
7. Sanderson, P., Finnegan, Y.E., Williams, C.M., Calder, P.C., Burdge, G.C., Wootton, S.A., Griffin, B.A., Millward, D.J., Pegge, N.C., and Bemelmans, W.J.E. (2002) UK Food Standards Agency α-Linolenic Acid Workshop Report, Br. J. Nutr. 88, 573-579.
8. Sinclair, A.J. (2003) Which of the n-3 PUFA Should Be Called Essential? Lipids 38, 1113-1114.
9. Lauritzen, L., and Hansen, H.S. (2003) Which of the n-3 FA Should Be Called Essential? Lipids 38, 889-891.
10. Ghafoorunissa, Vani, A., Laxmi, R., and Sesikeran, B. (2002) Effects of Dietary α-Linolenic Acid from Blended Oils on Biochemical Indices of Coronary Heart Disease in Indians, Lipids 37, 1077-1086.
11. Ghafoorunissa (1998) Requirement of Dietary Fats to Meet Nutritional Needs and Prevent the Risk of Atherosclerosis - An Indian Perspective, Ind. J. Med. Res. 108, 191-202.
12. Indu, M., and Ghafoorunissa (1992) n-3 Fatty Acids in Indian Diets - Comparison of the Effects of Precursor (α-linolenic acid) vs. Product (long chain n-3 polyunsaturated fatty acids), Nutr. Res. 12, 569-582.
13. Beare-Rogers, J.A. (1977) Docosaenoic Acid in Dietary Fats, in Progress in Chemistry of Fats and Other Lipids (Holman, R.T. ed.), Vol. 15, pp. 29-56, Pergamon Press, Paris.
14. Caughey, G.E., Mantzioris, E., Gibson, R.A., Cleland, L.G., and James, M.J. (1996) The Effect on Human Tumor Necrosis Factor Alpha and Interleukin 1 Beta Production of Diets Enriched in n-3 Fatty Acids from Vegetable Oil or Fish Oil, Am. J. Clin. Nutr. 63, 116-122.
15. Cunnane, S.C., Ganguly, S., Menaard, C., Liede, A.C., Hamadeh, M.J., Chen, Z.Y., and Woolever, T. (1993) High α-Linolenic Acid Flaxseed (Linum usitatissimum). Some Nutritional Properties in Humans, Br. J. Nutr. 69, 443-453.
16. Jenkins, D.J.A., Kendall, C.W.C., Vidgen, E., Agarwal, S., Rao, A.V., Rosenberg, R.S., Diamandis, E.P., Novokmet, R., Mehling, C.C., Perera, T., et al. (1999) Health Aspects of Partially Defatted Flaxseed, Including Effects on Serum Lipids, Oxidative Measures and ex vivo Androgen and Progestin Activity: A Controlled Crossover Trial, Am. J. Clin. Nutr. 69, 395-402.
17. Schmidt, E.B. (1997) n-3 Fatty Acids and the Risk of Coronary Heart Disease, Dan. Med. Bull. 44, 1-22.
18. Aneja, R.P., and Murthy, T.N. (1991) Beneficial Effects of Ghee, Nature 350, 280.
19. Lee, K.N., Kritchevsky, D., and Pariza, M.W. (1994) Conjugated Linoleic Acid and Atherogenisis in Rabbits, Atherosclerosis 108, 19-25.
20. Bansal, P., and Kansal, V.K. (1996) Milk, Some Myths and Misconceptions, Ind. Dairyman 48, 25-31.
21. Gurr, M.I. (1999) Lipids in Nutrition and Health: A Reappraisal, Vol. 21, p. 240, The Oily Press, Dundee, Scotland.
22. Ramaprasad, T.R., Baskaran, V., Debnath, S., Sambaiah, K., Jayaprakasan, S.G., Shivakumara, M., and Lokesh, B.R. (2003) A Process for the Preparation of Cholesterol Lowering Health Beverage Mix, Indian Patent 526/Del/2003.
23. Nagendra, R., Mahadevamma, Baskaran, V., and Venkatrao, S. (1995) Shelf Life of Spray Dried Infant Formula Supplemented with Lactulose, J. Food Proc. Preserv. 19, 303-315.
24. American Institute of Nutrition (1997) Report on the American Institute of Nutrition Ad Hoc Committee on Standards for Nutritional Studies, J. Nutr. 107, 1340-1348.
25. Folch, J., Lees, M., and Sloane Stanley, G.H. (1957) A Simple Method for the Isolation and Purification of Total Lipids from Animal Tissues, J. Biol. Chem. 226, 497-509.
26. Searcy, R.L., and Bergquist, L.M. (1960) A New Color Reaction for the Quantification of Serum Cholesterol, Clin. Chim. Acta 5, 192-196.
27. Warnick, G.R., and Albers, J.J. (1978) A Comprehensive Evaluation of the Heparin-Manganese Chloride Precipitation Procedure for Estimating HDL-Cholesterol, J. Lipid Res. 19, 65-76.
28. Stewart, J.C.M. (1980) Colorimetric Estimation of Phospholipids with Ammonium Ferrothiocyanate, Anal. Biochem. 104, 10-14.
29. Fletcher, M.J. (1968) A Colorimetric Method for Estimating Serum Triacylglycerol, Clin. Chim. Acta 22, 303-307.
30. Morrison, M.R., and Smith, M. (1963) Preparation of Fatty Acid Methyl Esters and Dimethyl Acetyls from Lipids with Boron Fluoride Methanol, J. Lipid Res. 5, 600-608.
31. Fisher, R.A. (1970) Statistical Methods for Research Workers, 14th edn., Oliver and Boya, Edinburg.
32. Kitessa, S.M., Gulati, S.K., Simos, G.C., Ashes, J.R., Scott, T.W., Fleck, E., and Wynn, P.C. (2004) Supplementation of Grazing Dairy Cows with Rumen-Protected Tuna Oil Enriches Milk Fat with n-3 Fatty Acids Without Affecting Milk Production or Sensory Characteristics, Br. J. Nutr. 91, 271-277.
33. Gerster, H. (1998) Can Adults Adequately Convert α-Linolenic Acid (18:3n-3) to Eicosapentaenoic Acid (20:5n-3) and Docosahexaenoic Acid (22:6n-3), Intl. J. Vit. Nutr. Res. 68, 159-173.
34. Mantzioris, E., James, M.J., Gibson, R.A., and Cleland L.G. (1994) Dietary Substitution with α-Linolenic Acid-Rich Vegetable Oil Increases Eicosapentaenoic Acid Concentrations in Tissues, Am. J. Clin. Nutr. 59, 1304-1309.
35. Bazinet, R.P., McMillan, E.G., and Cunnane, S.C. (2003) Dietary α-Linolenic Acid Increases the n-3 PUFA Content of Sow's Milk and the Tissues of the Suckling Piglet, Lipids 38, 1045-1049.
36. Zhong, F., and Sinclair, A.J. (2000) Increased α-Linolenic Acid Intake Increases Tissue α-Linolenic Acid Content and Apparent Oxidation with Little Effect on Tissue Docosahexaenoic Acid in the Guinea Pig, Lipids 35, 395-400.
37. Lin, D.S., and Connors, W.E. (1990) Are the n-3 Fatty Acids from Dietary Fish Oil Deposited in the Triglyceride Stores of Adipose Tissue, Am. J. Clin. Nutr. 51, 535-539.
38. Okuno, M., Kajiwara, K., Imai, S., Kobayashi, T., Honma, N., Maki, T., Suruga, K., Goda, T., Takase, S., Muto, Y., and Moriwaki, H. (1997) Perilla Oil Prevents Excessive Growth of Visceral Adipose Tissue in Rats by Down-regulating Adipocyte Differentiation, J. Nutr. 127, 1752-1757.
39. Brenner, R.R. (1984) Effect of Unsaturated Acids on Membrane Structure and Kinetics, Prog. Lipid Res. 23, 69-96.
40. Abedin, L., Lien, E.L., Vingrys, A.J., and Sinclair, A.J. (1999) The Effect of Dietary α-Linolenic Acid Compared with Docosahexaenoic Acid on Brain, Retina, Liver, and Heart in the Guinea Pig, Lipids 34, 475-482.
41. Sheaff Greiner, R.C., Zhang, Q., Goodman, K.J., Giussani, D.A., Nathanielsz, P.W., and Brenna, J.T. (1996) Linoleate, α-Linolenate, and Docosahexaenoate Recycling into Saturated and Monounsaturated Fatty Acid Is a Major Pathway in Pregnant or Lactating Adults and Fetal or Infant Rhesus Monkeys, J. Lipid Res. 37, 2675-2686.
42. Anderson, G.J. (1994) Developmental Sensitivity of the Brain to Dietary n-3 Fatty Acids, J. Lipid Res. 35, 105-111.
43. Philbrick, D.J., Mahadevappa, V.G., Ackman, R.G., and Holub, B.J. (1987) Ingestion of Fish Oil or a Derived n-3 Fatty Acid Concentrate Containing Eicosapentaenoic Acid (EPA) Affects Fatty Acid Compositions of Individual Phospholipids of Rat Brain Sciatic Nerve and Retina, J. Nutr. 117, 1663-1670.