Preliminary FISH-based assessment of external dose for residents exposed on the techa river

Radiation Research

Volumn 177, Issue 1, 2012, Pages 84-91

  Vozilova, A V ^a   Shagina, N B ^a   Degteva, M O ^a   Edwards, A A ^b   Ainsbury, E A ^b   Moquet, J E ^b   Hone, P ^b   Lloyd, D C ^b   Fomina, J N ^c   Darroudi, F ^c  

^a URALS RESEARCH CENTER FOR RADIATION MEDICINE   (Russian Federation)

^b PUBLIC HEALTH ENGLAND   (United Kingdom)

^c LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

PLUTONIUM; RIVER WATER; STRONTIUM 89; STRONTIUM 90;

ADULT; AGED; ARTICLE; BONE MARROW; CHROMOSOME ANALYSIS; CHROMOSOME TRANSLOCATION; DIETARY INTAKE; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL RELEASE; FEASIBILITY STUDY; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GAMMA RADIATION; HUMAN; INGESTION; MALE; PRIORITY JOURNAL; RADIATION DOSE; RADIATION EXPOSURE; RADIOACTIVE CONTAMINATION; RADIOACTIVE WASTE; RIVER; RUSSIAN FEDERATION;

AGED; AGED, 80 AND OVER; CALIBRATION; ENVIRONMENTAL EXPOSURE; FEMALE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; LABORATORIES; MALE; MIDDLE AGED; RADIATION DOSAGE; RADIATION MONITORING; RIVERS; RUSSIA; STRONTIUM RADIOISOTOPES; TRANSLOCATION, GENETIC;

EID: 84255194003     PISSN: 00337587     EISSN: 19385404     Source Type: Journal    
DOI: 10.1667/RR2485.1     Document Type: Article

References (29)

1. Degteva MO, Shagina NB, Vorobiova MI, Anspaugh LR, Napier B. Re-evaluation of waterborne releases of radioactive materials from the "Mayak" Production Association into the Techa River in 1949-1951. Health Phys. Forthcoming. doi: 10.1097/ HP.0b013e318228159a.
2. Degteva MO, Vorobiova MI, Tolstykh EI, Shagina NB, Shishkina EA, Anspaugh LR, et al. Development of an improved dose reconstruction system for the Techa River population affected by the operation of the Mayak Production Association. Radiat Res 2006; 166:255-70. (Pubitemid 44051214)
3. Krestinina LY, Preston DL, Ostroumova EV, Degteva MO, Ron E, Vyushkova OV, et al. Protracted radiation exposure and cancer mortality in the Techa River Cohort. Radiat Res 2005; 164:602-11. (Pubitemid 41532554)
4. Krestinina LY, Davis F, Ostroumova EV, Epifanova SB, Degteva MO, Preston DL, et al. Solid cancer incidence and low-dose-rate radiation exposures in the Techa River Cohort: 1956-2002. Int J Epidemiol 2007; 36:1038-46. (Pubitemid 350018548)
5. Krestinina LY, Preston DL, Davis F, Epifanova SB, Ostroumova EV, Ron E, et al. Leukemia incidence among people exposed to chronic radiation from the contaminated Techa River, 1953-2005. Radiat Environ Biophys 2009; 99:1940-5.
6. Preston DL, Krestinina LY, Sokolnikov ME, Ron E, Davis FG, Ostroumova EV, et al. How much can we say about site-specific cancer radiation risks? Radiat Res 2010 174 816-24.
7. Degteva MO, Shagina NB, Tolstykh EI, Bougrov NG, Zalyapin VI, Anspaugh LR, et al. An approach to reduction of uncertainties in internal doses reconstructed for the Techa River population. Radiat Prot Dosimetry 2007; 127:480-5.
8. Degteva MO, Anspaugh LR, Akleyev AV, Jacob P, Ivanov DV, Wieser A, et al. Electron paramagnetic resonance and fluorescence in situ hybridization-based investigations of individual doses for persons living at Metlino in the upper reaches of the Techa River. Health Phys 2005; 88:139-53. (Pubitemid 40279124)
9. Bauchinger M, Salassidis K, Brasellmann H, Vozilova AV, Pressl S, Stephan G, et al. FISH-based analysis of stable translocations in a Techa River population. Int J Radiat Biol 1998; 73:605-12. (Pubitemid 28320030)
10. Akleyev AV, Kossenko MM, Silkina LA, Degteva MO, Yachmenyov VA, Awa A, et al. Health effects of radiation incidents in the southern Urals. Stem Cells 1995; 13 Suppl 1:58-68.
11. Vulpis N, Scarpa G. Induction of chromosome aberrations by 90Sr beta-particles in cultured human lymphocytes. Mutat Res 1986; 163:277-83. (Pubitemid 17181132)
12. Oliveira EM, Suzuki MF, do Nascimento PA, da Silva MA, Okazaki K. Evaluation of the effect of 90Sr beta-radiation on human blood cells by chromosome aberration and single cell gel electrophoresis (comet assay) analysis. Mutat Res 2001; 476:109-21. (Pubitemid 32402268)
13. Tucker JD. Low-dose ionizing radiation and chromosome translocations: a review of the major considerations for human biological dosimetry. Mutat Res 2008; 659:211-20.
14. Tolstykh EI, Degteva MO, Peremyslova LM, Shagina NB, Shishkina EA, Krivoshchapov VA, et al. Reconstruction of longlived radionuclide intakes for Techa riverside residents: Strontium-90. Health Phys 2011; 101:28-47.
15. Cytogenetic analysis for radiation dose assessment. A manual. Technical Reports Series No. 405. Vienna International Atomic Energy Agency; 2001
16. Finnon P, Lloyd DC, Edwards AA. Fluorescence in situ hybridization detection of chromosomal aberrations in human lymphocytes: applicability to biological dosimetry. Int J Radiat Biol 1995; 68:429-35.
17. Fomina J, Darroudi F, Natarajan AT. Accurate detection of true incomplete exchanges in human lymphocytes exposed to neutron radiation using chromosome painting in combination with a telomeric PNA probe. Int J Radiat Biol 2001; 77:1175-83. (Pubitemid 33111854)
18. Lucas JN, Deng W. Our views on issues in radiation biodosimetry based on chromosome translocation measured by FISH. Radiat Prot Dosimetry 2000; 88:77-86. (Pubitemid 30306071)
19. Morton NE. Parameters of the human genome. Proc Natl Acad Sci U S A 1991; 88:7474-6. (Pubitemid 21915174)
20. Darroudi F. Use of FISH translocations analysis for retrospective biological dosimetry: How stable are stable chromosome aberrations? Radiat Prot Dosimetry 2000 88 101-9 (Pubitemid 30306074)
21. Darroudi F, Natarajan AT. Application of FISH chromosome painting assay for dose reconstruction: State of the art and current views. Radiat Prot Dosimetry 2000; 88:51-8. (Pubitemid 30306068)
22. Sigurdson AJ, Hauptmann HM, Bhatti P, Sram RJ, Beskid O, Tawn EJ, et al. International study of factors affecting human chromosome. Mutat Res 2008; 652:112-21.
23. McCullach P, Nelder JA. Generalized linear models. 2nd ed. Boca Raton, FL Chapman & Hall/CRC; 1989
24. Edwards AA, Lindholm C, Darroudi F, Stephan G, Romm H, Barquinero J, et al. Review of translocations detected by FISH for retrospective biological dosimetry applications. Radiat Prot Dosimetry 2005; 113:395-402.
25. Bender MA, Awa AA, Brooks AL, Evans HJ, Groer PG, Littlefield LG, et al. Current status of cytogenetic procedures to detect and quantify previous exposures to radiation. Mutat Res 1988; 196:103-59.
26. Lucas JN, Hill F, Burk C, Fester T, Straume T. Dose-response curve for chromosome translocations measured in human lymphocytes exposed to 60Co gamma rays. Health Phys 1995; 68:761-5.
27. Savage JRK, Papworth DG, Bauchinger M, Natarajan AT, Pantelias GE, Griffin CS, et al. Constructing a 2B calibration curve for retrospective dose reconstruction. Radiat Prot Dosimetry 2000; 88:69-76. (Pubitemid 30306070)
28. Tawn EJ, Whitehouse CA, Tarone RE. FISH chromosome aberration analysis on retired radiation workers from the Sellafield nuclear facility. Radiat Res 2004; 162:249-56. (Pubitemid 39295425)
29. Napier BA, Shagina NB, Degteva MO, Tolstykh EI, Vorobiova MI, Anspaugh LR. Preliminary uncertainty analysis for the doses estimated using the Techa River Dosimetry System-2000. Health Phys 2001; 81:395-405. (Pubitemid 32868285)