Evaluation of the effect of 90Sr β-radiation on human blood cells by chromosome aberration and single cell gel electrophoresis (comet assay) analysis

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 476, Issue 1-2, 2001, Pages 109-121

  De Oliveira, Elaine Mendes ^a   Suzuki, Miriam Fussae ^a   Do Nascimento, Patrícia Alves ^a   Da Silva, Márcia Augusta ^a   Okazaki, Kayo ^a  

^a INSTITUTO DE PESQUISAS ENERGÉTICAS E NUCLEARES   (Brazil)

Author keywords

90Sr radiation; Chromosome aberration; DNA damage and repair; Dose response curve; Human blood cells; Microgel electrophoresis

Indexed keywords

STRONTIUM 90; COBALT; STRONTIUM;

ADULT; ANALYTIC METHOD; ARTICLE; BETA RADIATION; BLOOD CELL; CELL CYCLE; CHROMOSOME ABERRATION; CHROMOSOME NUMBER; COMET ASSAY; CONTROLLED STUDY; CYTOGENETICS; DICENTRIC CHROMOSOME; DNA DAMAGE; DOUBLE MINUTE CHROMOSOME; HUMAN; HUMAN CELL; IONIZING RADIATION; LINEAR ENERGY TRANSFER; MALE; NORMAL HUMAN; PRIORITY JOURNAL; RADIATION DOSE; RADIATION RESPONSE; COMPARATIVE STUDY; FEMALE; GAMMA RADIATION; IN VITRO STUDY; MUTATION; NUCLEOTIDE SEQUENCE; RADIATION EXPOSURE;

ADULT; BETA RAYS; BLOOD CELLS; CHROMOSOME ABERRATIONS; COBALT RADIOISOTOPES; COMET ASSAY; DNA DAMAGE; DNA MUTATIONAL ANALYSIS; FEMALE; GAMMA RAYS; HUMANS; MUTATION; STRONTIUM RADIOISOTOPES;

EID: 0035832356     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(01)00100-2     Document Type: Article

References (48)

1. The physics and chemistry of radiation absorption
2. Microdosimetric aspects of the induction of chromosome aberrations
3. The relationship between chromosome aberrations and low LET radiation dose to human lymphocytes
4. 60Co γ-radiation
5. Biological dosimetry in simulated in vitro partial irradiations
6. Am
7. Am contamination
8. Chromosome aberrations induced in human lymphocytes by neutron irradiation
9. 0 human lymphocytes by low doses of ionizing radiations of different quality
10. Cancer therapy using bone-seeking isotopes
11. The induction of chromosome aberrations in human lymphocytes by in vitro irradiation with β-particles from tritiated water
12. Relative biological effectiveness and dose rate effect of tritiated water on chromosomes in human lymphocytes and bone marrow cells
13. Targeted radionuclide therapy for bone metastases
14. Biological dosimetry of β-ray exposure from tritium using chromosome translocations in human lymphocytes analyzed by fluorescence in situ hybridization
15. 131I for differentiated thyroid carcinoma
16. 131I therapy for thyroid cancer
17. 131I exposure: Study in hyperthyroidism patients
18. Micronuclei in human lymphocytes as a biological dosimeter: Preliminary data following β-irradiation in vitro
19. Micronucleus induction in human lymphocytes: Comparative effects of X-rays, α-particles, β-particles and neutrons and implications for biological dosimetry
20. 90Sr β-particles in cultured human lymphocytes
21. 226Ra in man in relation to clinical findings
22. A simple technique for quantification of low levels of DNA damage in individual cells
23. Preservation of comet assay slides: Comparison with fresh slides
24. Bleomycin-induced DNA damage and its removal in lymphocytes of breast cancer patients studied by comet assay
25. Evaluation of radioinduced damage and repair capacity in blood lymphocytes of breast cancer patients
26. Quantification of low-level radiation exposure by conventional chromosome aberration analysis
27. Distribution of radiation induced lesions in human chromosome and dose effect relation analyzed with G-banding
28. Analysis of primary process in the formation of acentric fragments
29. Radiation-induced human chromosome aberrations: In vitro dose rate studies
30. Radiation-induced chromosome aberrations in lymphocytes from man and crabeating monkey: The dose-response relationship at low doses
31. Conventional radiation-biological dosimetry using frequencies of unstable chromosome aberrations
32. Cytogenetic dose estimates from in vitro samples from persons involved in real or suspected radiation exposures
33. In vitro human cytogenetics dose-response systems
34. An overview of radiation dosimetry by conventional cytogenetic methods
35. Chromosome aberrations dosimetry using human lymphocytes in simulated partial body irradiation
36. Application of conventional and FGP staining for the analysis of chromosomal aberrations induced by low levels of dose in human lymphocytes
37. Frequencies of chromosomal aberrations induced in human blood lymphocytes by low doses of X-rays
38. Chromosome aberrations in human lymphocytes: Effect of radiation quality, dose and dose rate
39. The repair of ionising radiation-induced damage to DNA
40. The single cell gel/comet assay: A microgel electrophoretic technique for the detection of DNA damage and repair in individual cells
41. Determination of radiation-induced damage in lymphocytes using the micronucleus and microgel electrophoresis comet assay
42. Enzymatic restriction of mammalian cell DNA: Evidence for double-strand breaks as potentially lethal lesions
43. Biochemistry DNA lesions
44. In vivo induction of apoptosis in human lymphocytes by therapeutic fractionated total body irradiation
45. Flow cytometry as a quantitative and sensitive method to evaluate low dose radiation induced apoptosis in vitro in human peripheral blood lymphocytes