-
1
-
-
77955293476
-
Evolution of an adenocarcinoma in response to selection by targeted kinase inhibitors
-
Jones, S. J. M. et al. Evolution of an adenocarcinoma in response to selection by targeted kinase inhibitors. Genome Biol. 11, R82 (2010).
-
(2010)
Genome Biol.
, vol.11
-
-
Jones, S.J.M.1
-
2
-
-
77951589703
-
Clinical assessment incorporating a personal genome
-
Ashley, E. A. et al. Clinical assessment incorporating a personal genome. Lancet 375, 1525-1535 (2010).
-
(2010)
Lancet
, vol.375
, pp. 1525-1535
-
-
Ashley, E.A.1
-
3
-
-
67249128399
-
Clopidogrel and the concept of high risk pharmacokinetics
-
Roden, D. M. & Stein, C. M. Clopidogrel and the concept of high risk pharmacokinetics. Circulation 11 9, 2127-2130 (2009).
-
(2009)
Circulation
, vol.119
, pp. 2127-2130
-
-
Roden, D.M.1
Stein, C.M.2
-
4
-
-
79955492923
-
Pharmacogenomics - The genetics of variable drug responses
-
in the press
-
Roden, D. M., Wilke, R. A., Kroemer, H. K. & Stein, C. M. Pharmacogenomics - the genetics of variable drug responses. Circulation (in the press).
-
Circulation
-
-
Roden, D.M.1
Wilke, R.A.2
Kroemer, H.K.3
Stein, C.M.4
-
5
-
-
70349929431
-
Association between CYP2D6 polymorphisms and outcomes among women with early stage breast cancer treated with tamoxifen
-
Schroth, W. et al. Association between CYP2D6 polymorphisms and outcomes among women with early stage breast cancer treated with tamoxifen. JAMA 302, 1429-1436 (2009).
-
(2009)
JAMA
, vol.302
, pp. 1429-1436
-
-
Schroth, W.1
-
6
-
-
77955082302
-
A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury
-
Singer, J. B. et al. A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury. Nature Genet. 42, 711-714 (2010).
-
(2010)
Nature Genet.
, vol.42
, pp. 711-714
-
-
Singer, J.B.1
-
7
-
-
21144448879
-
Effect of VKORC1 haplotypes on transcriptional regulation and warfarin dose
-
Rieder, M. J. et al. Effect of VKORC1 haplotypes on transcriptional regulation and warfarin dose. N. Engl. J. Med. 352, 2285-2293 (2005).
-
(2005)
N. Engl. J. Med.
, vol.352
, pp. 2285-2293
-
-
Rieder, M.J.1
-
8
-
-
33749339075
-
Cytochrome P450 2C19 loss-of-function polymorphism is a major determinant of clopidogrel responsiveness in healthy subjects
-
Hulot, J. S. et al. Cytochrome P450 2C19 loss-of-function polymorphism is a major determinant of clopidogrel responsiveness in healthy subjects. Blood 108, 2244-2247 (2006).
-
(2006)
Blood
, vol.108
, pp. 2244-2247
-
-
Hulot, J.S.1
-
9
-
-
51649110496
-
A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose
-
Cooper, G. M. et al. A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose. Blood 11 2, 1022-1027 (2008).
-
(2008)
Blood
, vol.112
, pp. 1022-1027
-
-
Cooper, G.M.1
-
10
-
-
69249219296
-
Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy
-
Shuldiner, A. R. et al. Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy. JAMA 302, 849-857 (2009).
-
(2009)
JAMA
, vol.302
, pp. 849-857
-
-
Shuldiner, A.R.1
-
11
-
-
70349292099
-
Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance
-
Ge, D. et al. Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance. Nature 461, 399-401 (2009).
-
(2009)
Nature
, vol.461
, pp. 399-401
-
-
Ge, D.1
-
12
-
-
67649859295
-
HLA?B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin
-
Daly, A. K. et al. HLA?B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin. Nature Genet. 41, 816-819 (2009).
-
(2009)
Nature Genet.
, vol.41
, pp. 816-819
-
-
Daly, A.K.1
-
13
-
-
70349956433
-
Finding the missing heritability of complex diseases
-
Manolio, T. A. et al. Finding the missing heritability of complex diseases. Nature 461, 747-753 (2009).
-
(2009)
Nature
, vol.461
, pp. 747-753
-
-
Manolio, T.A.1
-
14
-
-
77956030786
-
Inhibition of mutated, activated BRAF in metastatic melanoma
-
Flaherty, K. T. et al. Inhibition of mutated, activated BRAF in metastatic melanoma. N. Engl. J. Med. 363, 809-819 (2010).
-
(2010)
N. Engl. J. Med.
, vol.363
, pp. 809-819
-
-
Flaherty, K.T.1
-
15
-
-
77958478674
-
Biologically based treatment of EGFR-mutant non-small-cell lung cancer
-
Pao, W. & Chmielecki, J. Rational, biologically based treatment of EGFR-mutant non-small-cell lung cancer. Nature Rev. Cancer 10, 760-774 (2010).
-
(2010)
Nature Rev. Cancer
, vol.10
, pp. 760-774
-
-
Pao, W.1
Rational, C.J.2
-
16
-
-
60849097257
-
Estimation of warfarin dose with clinical and pharmacogenetic data
-
Klein T. E. et al. Estimation of warfarin dose with clinical and pharmacogenetic data. N. Engl. J. Med. 360, 753-764 (2009).
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 753-764
-
-
Klein, T.E.1
-
17
-
-
9644279534
-
In genetic control of disease does "race" matter?
-
Goldstein, D. B. & Hirschhorn, J. N. In genetic control of disease, does "race" matter? Nature Genet. 36, 1243-1244 (2004).
-
(2004)
Nature Genet.
, vol.36
, pp. 1243-1244
-
-
Goldstein, D.B.1
Hirschhorn, J.N.2
-
18
-
-
33847625851
-
How close have universal health systems come to achieving equity in use of curative services? A systematic review
-
Hanratty, B., Zhang, T. & Whitehead, M. How close have universal health systems come to achieving equity in use of curative services? A systematic review. Int. J. Health Serv. 37, 89-109 (2007).
-
(2007)
Int. J. Health Serv.
, vol.37
, pp. 89-109
-
-
Hanratty, B.1
Zhang, T.2
Whitehead, M.3
-
20
-
-
77951541774
-
Biobanking and pharmacogenomics
-
McCarty, C. A. & Wilke, R. A. Biobanking and pharmacogenomics. Pharmacogenomics 11, 637-642 (2010).
-
(2010)
Pharmacogenomics
, vol.11
, pp. 637-642
-
-
McCarty, C.A.1
Wilke, R.A.2
-
21
-
-
0035957261
-
Preprescription genotyping: Not yet ready for prime time, but getting there
-
Roden, D. M. & Brown, N. J. Preprescription genotyping: not yet ready for prime time, but getting there. Circulation 103, 1608-1610 (2001).
-
(2001)
Circulation
, vol.103
, pp. 1608-1610
-
-
Roden, D.M.1
Brown, N.J.2
-
22
-
-
70349627428
-
Opportunities and challenges for the NIH-an interview with Francis Collins. Interview by Robert Steinbrook
-
Collins, F. Opportunities and challenges for the NIH-an interview with Francis Collins. Interview by Robert Steinbrook. N. Engl. J. Med. 361, 1321-1323 (2009).
-
(2009)
N. Engl. J. Med.
, vol.361
, pp. 1321-1323
-
-
Collins, F.1
|