Heart rate acceleration of a subsidiary pacemaker by β-adrenergic stimulation

Korean Circulation Journal

Volumn 41, Issue 11, 2011, Pages 658-665

  Park, Sanghoon ^a   Park, Hyerim ^a   Hwang, Hye Jin ^a   Shim, Jaemin ^a   Sung, Jung Hoon ^b   Kim, Jong Youn ^a   Pak, Hui Nam ^a   Lee, Moon Hyoung ^a   Joung, Boyoung ^a  

^a Yonsei University College of Medicine   (South Korea)

^b CHA University   (South Korea)

Author keywords

Calcium channel; Sinoatrial node; Sympathetic nervous system

Indexed keywords

4 (N ETHYL N PHENYLAMINO) 1,2 DIMETHYL 6 (METHYLAMINO)PYRIMIDINIUM CHLORIDE; CALCIUM CHANNEL; ISOPRENALINE; RYANODINE; THAPSIGARGIN;

ACCELERATION; ANIMAL EXPERIMENT; ARTICLE; BETA ADRENERGIC STIMULATION; HEART RATE; HEART RIGHT ATRIUM; NONHUMAN; PACEMAKER; SARCOPLASMIC RETICULUM; SINUS NODE; SINUS RHYTHM;

EID: 84255171042     PISSN: 17385520     EISSN: 17385555     Source Type: Journal    
DOI: 10.4070/kcj.2011.41.11.658     Document Type: Article

References (27)

1. Adán V, Crown LA. Diagnosis and treatment of sick sinus syndrome. Am Fam Physician 2003;67:1725-32.
2. Randall WC, Talano J, Kaye MP, Euler D, Jones S, Brynjolfsson G. Cardiac pacemakers in absence of the SA node: responses to exercise and autonomic blockade. Am J Physiol 1978;234:H465-70. (Pubitemid 9125773)
3. Rozanski GJ, Lipsius SL, Randall WC. Functional characteristics of sinoatrial and subsidiary pacemaker activity in the canine right atrium. Circulation 1983;67:1378-87. (Pubitemid 13105364)
4. DiFrancesco D. Pacemaker mechanisms in cardiac tissue. Annu Rev Physiol 1993;55:455-72. (Pubitemid 23102141)
5. DiFrancesco D. The pacemaker current (l(f)) plays an important role in regulating SA node pacemaker activity. Cardiovasc Res 1995;30:307-8.
6. Hata T, Noda T, Nishimura M, Watanabe Y. The role of Ca2+ release from sarcoplasmic reticulum in the regulation of sinoatrial node automaticity. Heart Vessels 1996;11:234-41.
7. Ju YK, Allen DG. Intracellular calcium and Na+-Ca2+ exchange current in isolated toad pacemaker cells. J Physiol 1998;508:153-66. (Pubitemid 28167578)
8. Bogdanov KY, Vinogradova TM, Lakatta EG. Sinoatrial nodal cell ryanodine receptor and Na(+)-Ca(2+) exchanger: molecular partners in pacemaker regulation. Circ Res 2001;88:1254-8. (Pubitemid 32587841)
9. Vinogradova TM, Bogdanov KY, Lakatta EG. Beta-adrenergic stimulation modulates ryanodine receptor Ca(2+) release during diastolic depolarization to accelerate pacemaker activity in rabbit sinoatrial nodal cells. Circ Res 2002;90:73-9. (Pubitemid 34074611)
10. Vinogradova TM, Zhou YY, Maltsev V, Lyashkov A, Stern M, Lakatta EG. Rhythmic ryanodine receptor Ca2+ releases during diastolic depolarization of sinoatrial pacemaker cells do not require membrane depolarization. Circ Res 2004;94:802-9. (Pubitemid 38451742)
11. Vinogradova TM, Lyashkov AE, Zhu W, et al. High basal protein kinase A-dependent phosphorylation drives rhythmic internal Ca2+ store oscillations and spontaneous beating of cardiac pacemaker cells. Circ Res 2006;98:505-14.
12. Joung B, Tang L, Maruyama M, et al. Intracellular calcium dynamics and acceleration of sinus rhythm by beta-adrenergic stimulation. Circulation 2009;119:788-96.
13. Joung B, Ogawa M, Lin SF, Chen PS. The calcium and voltage clocks in sinoatrial node automaticity. Korean Circ J 2009;39:217-22.
14. Joung B, Shinohara T, Zhang H, et al. Tachybradycardia in the isolated canine right atrium induced by chronic sympathetic stimulation and pacemaker current inhibition. Am J Physiol Heart Circ Physiol 2010;299:H634-42.
15. A comparison of antiarrhythmic-drug therapy with implantable defibrillators in patients resuscitated from near-fatal ventricular arrhythmias: the Antiarrhythmics versus Implantable Defibrillators (AVID) Investigators. N Engl J Med 1997;337:1576-83.
16. Joung BY, Koo BK, Xu ZZ, Kim IK, Lee MH, Kim US. The effects of obstacles on the dynamics of ventricular fibrillation. Korean Circ J 2005;35:183-91.
17. Fedorov W, Schuessler RB, Hemphill M, et al. Structural and functional evidence for discrete exit pathways that connect the canine sinoatrial node and atria. Circ Res 2009;104:915-23.
18. Efimov IR, Fedorov W, Joung B, Lin SF. Mapping cardiac pacemaker circuits: methodological puzzles of the sinoatrial node optical mapping. Circ Res 2010;106:255-71.
19. Boineau JP, Schuessler RB, Mooney CR, et al. Multicentric origin of the atrial depolarization wave: the pacemaker complex: relation to dynamics of atrial conduction, P-wave changes and heart rate control. Circulation 1978;58:1036-48. (Pubitemid 9091986)
20. Boineau JP, Miller CB, Schuessler RB, et al. Activation sequence and potential distribution maps demonstrating multicentric atrial impulse origin in dogs. Circ Res 1984;54:332-47. (Pubitemid 14172444)
21. Dobrzynski H, Boyett MR, Anderson RH. New insights into pacemaker activity: promoting understanding of sick sinus syndrome. Circulation 2007;115:1921-32. (Pubitemid 46598906)
22. Rubenstein DS, Lipsius SL. Mechanisms of automaticity in subsidiary pacemakers from cat right atrium. Circ Res 1989;64:648-57. (Pubitemid 19105301)
23. Verheijck EE, van Kempen MJ, Veereschild M, Lurvink J, Jongsma HJ, Bouman LN. Electrophysiological features of the mouse sinoatrial node in relation to connexin distribution. Cardiovasc Res 2001;52:40-50. (Pubitemid 32835237)
24. Lei M, Jones SA, Liu J, et al. Requirement of neuronal- and cardiac-type sodium channels for murine sinoatrial node pacemaking. J Physiol 2004;559:835-48. (Pubitemid 39276172)
25. Lancaster MK, Jones SA, Harrison SM, Boyett MR. Intracellular Ca2+ and pacemaking within the rabbit sinoatrial node: heterogeneity of role and control. J Physiol 2004;556:481-94. (Pubitemid 38579001)
26. Tellez JO, Dobrzynski H, Greener ID, et al. Differential expression of ion channel transcripts in atrial muscle and sinoatrial node in rabbit. Circ Res 2006;99:1384-93. (Pubitemid 44949674)
27. Efimov IR, Nikolski VP, Salama G. Optical imaging of the heart. Circ Res 2004;95:21-33. (Pubitemid 38931832)