In situ Raman imaging combined with computational fluid dynamics for measuring concentration profiles during mixing processes

Chemical Engineering Journal

Volumn 179, Issue , 2012, Pages 338-348

  Rinke, Günter ^a   Wenka, Achim ^a   Roetmann, Karsten ^b   Wackerbarth, Hainer ^b  

^a KARLSRUHE INSTITUTE OF TECHNOLOGY   (Germany)

^b LASER LABORATORIUM GÖTTINGEN E V   (Germany)

Author keywords

CFD; Light sheets; Micro mixer; Raman imaging

Indexed keywords

CONCENTRATION MAPS; CONCENTRATION PROFILES; CONSTANT TEMPERATURE; IN-SITU; LASER-LIGHT SHEETS; LATERAL RESOLUTION; LIFE-SCIENCES; LIGHT SHEET; LIGHT SHEETS; MICRO MIXER; MICRO MIXERS; MIXING PROCESS; NON-STEADY-STATE CONDITIONS; PIXEL SIZE; RAMAN IMAGING; SINGLE SHOTS; STANDARD DEVIATION; TWO-COMPONENT;

CCD CAMERAS; CONCENTRATION (PROCESS); ETHANOL; LAMINAR FLOW; MIXERS (MACHINERY); MIXING; OPTICAL INSTRUMENTS; QUARTZ;

COMPUTATIONAL FLUID DYNAMICS;

EID: 84155194908     PISSN: 13858947     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cej.2011.11.016     Document Type: Article

References (29)

1. Hinsmann P., et al. Design, simulation and application of a new micromixing device for time resolved infrared spectroscopy of chemical reactions in solution. Lab on a Chip 2001, 1:16-21.
2. Antes J., Boskovic D., Krause H., Loebbecke S., Lutz N., Tuercke T., Schweikert W. Analysis and improvement of strong exothermic nitrations in microreactors. Chemical Engineering Research and Design 2003, 81:760-765.
3. Keoschkerjan R., Richter M., Boskovic D., Schnürer F., Löbbecke S. Novel multifunctional microreaction unit for chemical engineering. Chemical Engineering Journal 2004, 101:469-475.
4. Floyd T.M., Schmidt M.A., Jensen K.F. Silicon micromixers with infrared detection for studies of liquid-phase reactions. Industrial & Engineering Chemistry Research 2005, 44:2351-2358.
5. Salmon J.B., Ajdari A., Tabeling P., Servant L., Talaga D., Joanicot M. In situ Raman imaging of interdiffusion in a microchannel. Applied Physics Letters 2005, 86:094106.
6. Rinke G., Ewinger A., Kerschbaum S., Rinke M. In situ Raman spectroscopy to monitor the hydrolysis of acetal in microreactors. Microfluidics and Nanofluidics 2011, 10:145-153.
7. Park T., Lee M., Choo J., Kim Y.S., Lee E.K., Kim D.J., Lee S.H. Analysis of passive mixing behavior in a poly(dimethylsiloxane) microfluidic channel using confocal fluorescence and Raman microscopy. Applied Spectroscopy 2004, 58:1172-1179.
8. Sarrazin F., Salmon J.-B. Chemical reaction imaging within microfluidic devices using confocal Raman spectroscopy: the case of water and deuterium oxide as a model system. Analytical Chemistry 2008, 80:1689-1695.
9. Ewinger A., Rinke G., Kerschbaum S., Rinke M., Schubert K. Raman-spectroscopy for measuring chemical reactions in micro reactors. Proceedings of the 6th International Conference on Nanochannels, Microchannels, and Minichannels, ICNMM 2008 (PART A) 2008, 747-748.
10. Roetmann K., Schmunk W., Garbe C., Beushausen V. Micro-flow analysis by molecular tagging velocymetry and planar Raman-scatttering. Experiments in Fluids 2008, 44:419-430.
11. Lee M., Lee J.P., Rhee H., Choo J., Chai Y.G., Lee E.K. Applicability of laser-induced Raman microscopy for in situ monitoring of imine formation in a glass microfluidic chip. Journal of Raman Spectroscopy 2003, 34:737-742.
12. Leung S.A., Winkle R.F., Wootton R.C.R., deMello A.J. A method for rapid reaction optimisation in continuous-flow microfluidic reactors using online Raman spectroscopic detection. Analyst 2004, 130:46-51.
13. Sung C.J., Liu J.B., Law C.K. Structural response of counterflow diffusion flames to strain rate variations. Combustion and Flame 1995, 102:481-492.
14. Luo C., Moghtaderi B., Kennedy E., Dlugogorski B. Three-dimensional numerical study on flames. Chemical Product and Process Modeling 2009, 4. art. no. 10.
15. Egawa T., Durand J.L., Hayden E.Y., Rousseau D.L., Yeh D.-R. Design and evaluation of a passive alcove-based microfluidic mixer. Analytical Chemistry 2009, 81:1622-1627.
16. Hoffmann M., Schlüter M., Räbiger N. Experimental investigation of liquid-liquid mixing in T-shaped micro-mixers using μ-LIF and μ-PIV. Chemical Engineering Science 2006, 61:2968-2976.
17. Hessel V., Renken A., Schouten J.C., Yoshida J. Micro Process Engineering: A Comprehensive Handbook 2009, Wiley-VCH, Weinheim.
18. Wirth T. Microreactors in Organic Synthesis and Catalysis 2008, Wiley-VCH, Weinheim.
19. Watts P., Wiles C. Recent advances in synthetic micro reaction technology. Chemical Communications 2007, 5:443-467.
20. Mills P.L., Quiram D.J., Ryley J.F. Microreactor, technology and process miniaturization for catalytic reactions. A perspective on recent developments and emerging technologies. Chemical Engineering Science 2007, 62:6992-7010.
21. Müller A., Cominos V., Hessel V., Horn B., Schürer J., Ziogas A., Jähnisch K., Hillmann V., Großer V., Jam K.A., Bazzanella A., Rinke G., Kraut M. Fluidic bus system for chemical process engineering in the laboratory and for small-scale production. Chemical Engineering Journal 2005, 107:205-214.
22. Nguyen N.T. Micromixers, Fundamentals, Design and Fabrication 2008, Elsevier, ISBN 10: 0-8155-1543-X.
23. Nguyen N.T., Wu Z. Micromixers-a review. Journal of Micromechanics and Microengineering 2005, 15:R1-R16.
24. Brandner J.J., Bohn L., Henning T., Schygulla U., Schubert K. Microstructure heat exchanger applications in laboratory and industry. Heat Transfer Engineering 2007, 28:761-771.
25. Bohn L., Braune S., Kotthaus M., Kraut M., Pöchlauer P., Vorbach M., Wenka A., Schubert K. First large-scale application of microreaction technology within commercial chemical production of DSM. Proceedings of the 9th International Conference on Microreaction Technology 2006, 379-380.
26. Rinke G., Kerschbaum S., Wenka A., Holpe H. Micro process engineering for industrial production of biodiesel. Proceedings of the 9th International Conference on Microreaction Technology IMRET9 2006, 257-258.
27. Batchelor G.K. An Introduction to Fluid Dynamics 2000, Cambridge Univ. Press, Cambridge, England.
28. Versteeg H., Malalasekra W. An Introduction to Computational Fluid Dynamics: The Finite Volume Method 2007, Prentice Hall. 2nd ed.
29. Kölbl A., Kraut M., Schubert K. The iodide iodate method to characterize microstructured mixing devices. AIChE Journal 2008, 54:639-645.