Binding to PLA 2 may contribute to the anti-inflammatory activity of catechol

Chemical Biology and Drug Design

Volumn 79, Issue 1, 2012, Pages 143-147

  Dileep, Kalarickal V ^a   Tintu, Ignatius ^a   Mandal, Pradeep K ^b   Karthe, Ponnuraj ^b   Haridas, Madathilkovilakathu ^a   Sadasivan, Chittalakkottu ^a  

^a KANNUR UNIVERSITY   (India)

^b UNIVERSITY OF MADRAS   (India)

Author keywords

Anti inflammatory; Catechol; Crystal structure; Enzyme inhibition; PLA 2

Indexed keywords

CATECHOL; LIPOXYGENASE; PHOSPHOLIPASE A2; PHOSPHOLIPASE A2 INHIBITOR; POLYPHENOL DERIVATIVE; PROSTAGLANDIN SYNTHASE; ANTIINFLAMMATORY AGENT; CATECHOL DERIVATIVE; ENZYME INHIBITOR;

ANTIINFLAMMATORY ACTIVITY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME KINETICS; INFLAMMATION; LETTER; PRIORITY JOURNAL; BINDING SITE; CHEMISTRY; COMPUTER SIMULATION; DRUG ANTAGONISM; DRUG EFFECT; KINETICS; METABOLISM; PROTEIN BINDING; X RAY CRYSTALLOGRAPHY;

ANTI-INFLAMMATORY AGENTS; BINDING SITES; CATALYTIC DOMAIN; CATECHOLS; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; KINETICS; PHOSPHOLIPASES A2; PROTEIN BINDING;

EID: 84155167896     PISSN: 17470277     EISSN: 17470285     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2011.01258.x     Document Type: Letter

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