Long-term perturbation of muscle iron homeostasis following hindlimb suspension in old rats is associated with high levels of oxidative stress and impaired recovery from atrophy

Experimental Gerontology

Volumn 47, Issue 1, 2012, Pages 100-108

  Xu, Jinze ^a   Hwang, Judy C Y ^a   Lees, Hazel A ^a   Wohlgemuth, Stephanie E ^a   Knutson, Mitchell D ^a   Judge, Andrew R ^a   Dupont Versteegden, Esther E ^b   Marzetti, Emanuele ^a,c   Leeuwenburgh, Christiaan ^a  

^a UNIVERSITY OF FLORIDA   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

^c CATHOLIC UNIVERSITY   (Italy)

Author keywords

Aging; Hindlimb unloading and re loading; Iron metabolism; Sarcopenia; Skeletal muscle atrophy

Indexed keywords

4 HYDROXYNONENAL; 8 HYDROXYGUANINE; CARRIER PROTEIN; CD71 ANTIGEN; FERROPORTIN; IRON; MESSENGER RNA; NATURAL RESISTANCE ASSOCIATED MACROPHAGE PROTEIN 2; PROTEIN ZIP14; UNCLASSIFIED DRUG;

AGE; AGED; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GASTROCNEMIUS MUSCLE; HOMEOSTASIS; IMMOBILIZATION; IRON OVERLOAD; IRON TRANSPORT; MALE; MUSCLE ATROPHY; MUSCLE MASS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; BODY WEIGHT; CATION TRANSPORT PROTEINS; DNA; HINDLIMB SUSPENSION; HOMEOSTASIS; IRON; LIPID PEROXIDATION; MALE; MEMBRANE PROTEINS; MUSCLE, SKELETAL; MUSCULAR ATROPHY; OXIDATION-REDUCTION; OXIDATIVE STRESS; RATS; RATS, INBRED F344; RECEPTORS, TRANSFERRIN; RECOVERY OF FUNCTION; RNA; TYROSINE;

ANIMALIA; RATTUS; RATTUS NORVEGICUS;

EID: 84155167702     PISSN: 05315565     EISSN: 18736815     Source Type: Journal    
DOI: 10.1016/j.exger.2011.10.011     Document Type: Article

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